Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jip Zonderland"'
Publikováno v:
MethodsX, Vol 10, Iss , Pp 102139- (2023)
Externí odkaz:
https://doaj.org/article/59180b7283564b5686dc11e64af3e1d1
Publikováno v:
MethodsX, Vol 6, Iss , Pp 2562-2569 (2019)
Changes in actin structure and distribution are involved in many cellular processes, such as differentiation, proliferation and migration. Differences in cell shape and size make the analysis of actin distribution difficult. Here, we have developed a
Externí odkaz:
https://doaj.org/article/14107f5caf6245ed878a7878a679a193
Autor:
Vahid Ansari, Andrea Calore, Jip Zonderland, Jules A. W. Harings, Lorenzo Moroni, Katrien V. Bernaerts
Publikováno v:
Biomacromolecules, 23(3), 1083-1100. American Chemical Society
alpha-Amino acid based polyester amides (PEAs) are promising candidates for additive manufacturing (AM), as they unite the flexibility and degradability of polyesters and good thermomechanical properties of polyamides in one structure. Introducing al
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology, 3(1):576. Nature Publishing Group
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology, 3(1):576. Nature Publishing Group
Both biological and mechanical signals are known to influence cell proliferation. However, biological signals are mostly studied in two-dimensions (2D) and the interplay between these different pathways is largely unstudied. Here, we investigated the
Autor:
Jip Zonderland
Cell behavior is relatively well studied in 2D petridishes, but not in a 3D environment. Increasing evidence shows a large difference in cell behavior in 3D vs 2D. This thesis is focussed on exploring the extent and consequences of these differences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af273d06e8b37541872aa93dded658d
https://doi.org/10.26481/dis.20200701jz
https://doi.org/10.26481/dis.20200701jz
Publikováno v:
Biomaterials, 240:119854, 1-13. ELSEVIER SCI LTD
Biomaterials
Biomaterials
Mechanosensing proteins have mainly been investigated in 2D culture platforms, while understanding their regulation in 3D enviroments is critical for tissue engineering. Among mechanosensing proteins, the actin cytoskeleton plays a key role in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55a9c33b53adf254994860f3d836731
https://cris.maastrichtuniversity.nl/en/publications/ef3fb122-3425-455b-9ead-8cf506201799
https://cris.maastrichtuniversity.nl/en/publications/ef3fb122-3425-455b-9ead-8cf506201799
Publikováno v:
Biomedical Materials
Biomedical Materials, 15(4):045020. IOP Publishing Ltd.
Biomedical Materials, 15(4):045020. IOP Publishing Ltd.
Developing, homeostatic, and regenerating tissues are full of various gradients, including mechanical, chemical, porosity and growth-factor gradients. However, it remains challenging to replicate these gradients using common tissue engineering approa
Autor:
P.J. Emans, Ana Henriques Ferreira Lourenco, Pamela Habibovic, Lorenzo Moroni, Andrada Serafim, Marloes J. M. Peters, Hong Liu, David B. Gomes, Peter Kessler, Silvia Rezzola, Izabela-Cristina Stancu, Sandra Camarero Espinosa, Paul Wieringa, Nicole D. Bouvy, David Koper, Jip Zonderland
Publikováno v:
bioRxiv
Electrospun (ESP) scaffolds are a promising type of tissue engineering constructs for large defects with limited depth. To form new functional tissue, the scaffolds need to be infiltrated with cells, which will deposit extracellular matrix. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa3fdca2655d3a33e9cefd31fc30f0d
Controlling basic fibroblast growth factor (bFGF) signaling is important for both tissue-engineering purposes, controlling proliferation and differentiation potential, and for cancer biology, influencing tumor progression and metastasis. Here, we obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41dd6abd30f79c0448bc64f52b9d6b36
https://doi.org/10.1101/782243
https://doi.org/10.1101/782243
Autor:
Corry M.R. Weemaes, M.H.D. Schoenaker, Stefanie S. V. Henriet, Marcel van Deuren, Ingrid Pico-Knijnenburg, Jip Zonderland, Sandra J. Posthumus-van Sluijs, Hanna IJspeert, Qiang Pan-Hammarström
Publikováno v:
Journal of Clinical Immunology
Journal of Clinical Immunology, 38(1), 35-44. Springer New York
Journal of Clinical Immunology, 38, 35-44
Journal of Clinical Immunology, 38, 1, pp. 35-44
Journal of Clinical Immunology, 38(1), 35-44. Springer New York
Journal of Clinical Immunology, 38, 35-44
Journal of Clinical Immunology, 38, 1, pp. 35-44
Bloom’s syndrome (BS) is an autosomal recessive disease, caused by mutations in the BLM gene. This gene codes for BLM protein, which is a helicase involved in DNA repair. DNA repair is especially important for the development and maturation of the