Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jip Ramaker"'
Autor:
Esther E. E. Drees, Nils J. Groenewegen, Sandra A. W. M. Verkuijlen, Monique A. J. vanEijndhoven, Jip Ramaker, Pepijn Veenstra, Mirjam Hussain, Catharina G. M. Groothuis‐Oudshoorn, Daphne deJong, Josée M. Zijlstra, Johan deRooij, D. Michiel Pegtel
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 7, Pp n/a-n/a (2024)
Abstract Previously, we showed that quantification of lymphoma‐associated miRNAs miR‐155‐5p, ‐127‐3p and let‐7a‐5p levels in plasma extracellular vesicles (EVs) report treatment response in patients with classic Hodgkin lymphoma (cHL).
Externí odkaz:
https://doaj.org/article/61f123c0de464cf2954835bebd3965e3
Autor:
Ymke van der Pol, Normastuti Adhini Tantyo, Nils Evander, Anouk E Hentschel, Birgit MM Wever, Jip Ramaker, Sanne Bootsma, Marieke F Fransen, Kristiaan J Lenos, Louis Vermeulen, Famke L Schneiders, Idris Bahce, Jakko A Nieuwenhuijzen, Renske DM Steenbergen, D Michiel Pegtel, Norbert Moldovan, Florent Mouliere
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp 1-10 (2023)
Abstract Cell‐free DNA (cfDNA) can be isolated and sequenced from blood and/or urine of cancer patients. Conventional short‐read sequencing lacks deployability and speed and can be biased for short cfDNA fragments. Here, we demonstrate that with
Externí odkaz:
https://doaj.org/article/b680ea20f07b4e7887161c9b62d150f1
Autor:
Ymke van der Pol, Norbert Moldovan, Jip Ramaker, Sanne Bootsma, Kristiaan J. Lenos, Louis Vermeulen, Shahneen Sandhu, Idris Bahce, D. Michiel Pegtel, Stephen Q. Wong, Sarah-Jane Dawson, Dineika Chandrananda, Florent Mouliere
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-16 (2023)
Abstract Background Existing methods to detect tumor signal in liquid biopsy have focused on the analysis of nuclear cell-free DNA (cfDNA). However, non-nuclear cfDNA and in particular mitochondrial DNA (mtDNA) has been understudied. We hypothesize t
Externí odkaz:
https://doaj.org/article/f391dac559774ebc9fe41ed580f121ff
Autor:
Mafalda Antunes-Ferreira, Silvia D’Ambrosi, Mohammad Arkani, Edward Post, Sjors G. J. G. In ‘t Veld, Jip Ramaker, Kenn Zwaan, Ece Demirel Kucukguzel, Laurine E. Wedekind, Arjan W. Griffioen, Mirjam Oude Egbrink, Marijke J. E. Kuijpers, Daan van den Broek, David P. Noske, Koen J. Hartemink, Siamack Sabrkhany, Idris Bahce, Nik Sol, Harm-Jan Bogaard, Danijela Koppers-Lalic, Myron G. Best, Thomas Wurdinger
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Liquid biopsy approaches offer a promising technology for early and minimally invasive cancer detection. Tumor-educated platelets (TEPs) have emerged as a promising liquid biopsy biosource for the detection of various cancer types. In this s
Externí odkaz:
https://doaj.org/article/9358e61d08a441cdb79204397fabd108
Autor:
Mohammad Arkani, Azar Kianzad, Samara Jansen, A. Josien Smits, Edward Post, Jip Ramaker, Tonny Lagerweij, Sjors G. J. G. In’t Veld, David P. Noske, Anton Vonk Noordegraaf, Thomas Wurdinger, Myron G. Best, Harm‐Jan Bogaard
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 13 (2023)
Background Appropriate treatment of pulmonary hypertension (PH) is critically dependent on accurate discrimination between pre‐ and postcapillary PH. However, clinical discrimination is challenging and frequently requires a right heart catheterizat
Externí odkaz:
https://doaj.org/article/2bb1340cd1964acd909e02176b39be30
Autor:
Nik Sol, Sjors G.J.G. in ‘t Veld, Adrienne Vancura, Maud Tjerkstra, Cyra Leurs, François Rustenburg, Pepijn Schellen, Heleen Verschueren, Edward Post, Kenn Zwaan, Jip Ramaker, Laurine E. Wedekind, Jihane Tannous, Bauke Ylstra, Joep Killestein, Farrah Mateen, Sander Idema, Philip C. de Witt Hamer, Anna C. Navis, William P.J. Leenders, Ann Hoeben, Bastiaan Moraal, David P. Noske, W. Peter Vandertop, R. Jonas A. Nilsson, Bakhos A. Tannous, Pieter Wesseling, Jaap C. Reijneveld, Myron G. Best, Thomas Wurdinger
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 7, Pp 100101- (2020)
Summary: Tumor-educated platelets (TEPs) are potential biomarkers for cancer diagnostics. We employ TEP-derived RNA panels, determined by swarm intelligence, to detect and monitor glioblastoma. We assessed specificity by comparing the spliced RNA pro
Externí odkaz:
https://doaj.org/article/3c63ceb85e20460e8535824c45ce6bd6
Autor:
Ymke van der Pol, Normastuti Adhini Tantyo, Nils Evander, Anouk E. Hentschel, Jip Ramaker, Idris Bahce, Jakko A. Nieuwenhuijzen, Renske D.M. Steenbergen, D. Michiel Pegtel, Norbert Moldovan, Florent Mouliere
Cell-free DNA (cfDNA) can be isolated from blood and/or urine of cancer patients and analyzed with sequencing. Unfortunately, most conventional short-read sequencing methods are technically challenging, labor intensive and time consuming, requiring s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::565f438f1953a910c9a0b03dd84064f3
https://doi.org/10.1101/2022.08.11.22278674
https://doi.org/10.1101/2022.08.11.22278674
Autor:
Ymke van der Pol, Norbert Moldovan, Sandra Verkuijlen, Jip Ramaker, Dries Boers, Wendy Onstenk, Johan de Rooij, Idris Bahce, D Michiel Pegtel, Florent Mouliere
Publikováno v:
van der Pol, Y, Moldovan, N, Verkuijlen, S, Ramaker, J, Boers, D, Onstenk, W, de Rooij, J, Bahce, I, Pegtel, D M & Mouliere, F 2022, ' The Effect of Preanalytical and Physiological Variables on Cell-Free DNA Fragmentation ', Clinical Chemistry, vol. 68, no. 6, pp. 803-813 . https://doi.org/10.1093/clinchem/hvac029
Clinical Chemistry, 68(6), 803-813
Clinical Chemistry, 68(6), 803-813
BackgroundAssays that account for the biological properties and fragmentation of cell-free DNA (cfDNA) can improve the performance of liquid biopsy. However, preanalytic and physiological differences between individuals on fragmentomic analysis are p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32ce0551ecead9265eb222612986c06
https://research.vumc.nl/en/publications/6586d772-4522-4a1d-af1d-7028808e23db
https://research.vumc.nl/en/publications/6586d772-4522-4a1d-af1d-7028808e23db
Autor:
A. Josien Smits, Mohammad Arkani, Sjors G.J.G. In ’t Veld, Anna E. Huis in ‘t Veld, Nik Sol, Joanne A. Groeneveldt, Liza Botros, Natalia J. Braams, Samara M.A. Jansen, Jip Ramaker, Kenn Zwaan, Edward Post, Esther J. Nossent, Anco Boonstra, Frances S. de Man, Anton Vonk Noordegraaf, Jose Gomez-Arroyo, Myron G. Best, Tom Wurdinger, Harm Jan Bogaard
Publikováno v:
Annals of the American Thoracic Society, 19(10), 1650-1660. American Thoracic Society
Smits, A J, Arkani, M, In 't Veld, S G J G, Huis In 't Veld, A E, Sol, N, Groeneveldt, J A, Botros, L, Braams, N J, Jansen, S M, Ramaker, J, Zwaan, K, Post, E, Nossent, E J, Boonstra, A, de Man, F S, Vonk Noordegraaf, A, Gomez-Arroyo, J, Best, M G, Wurdinger, T & Bogaard, H J 2022, ' Distinct Platelet Ribonucleic Acid Signatures in Patients with Pulmonary Hypertension ', Annals of the American Thoracic Society, vol. 19, no. 10, pp. 1650-1660 . https://doi.org/10.1513/AnnalsATS.202201-085OC
Smits, A J, Arkani, M, In 't Veld, S G J G, Huis In 't Veld, A E, Sol, N, Groeneveldt, J A, Botros, L, Braams, N J, Jansen, S M, Ramaker, J, Zwaan, K, Post, E, Nossent, E J, Boonstra, A, de Man, F S, Vonk Noordegraaf, A, Gomez-Arroyo, J, Best, M G, Wurdinger, T & Bogaard, H J 2022, ' Distinct Platelet Ribonucleic Acid Signatures in Patients with Pulmonary Hypertension ', Annals of the American Thoracic Society, vol. 19, no. 10, pp. 1650-1660 . https://doi.org/10.1513/AnnalsATS.202201-085OC
Rationale: Pulmonary hypertension encompasses progressive disorders leading to right ventricular dysfunction and early death. Late detection is an important cause of poor clinical outcomes. However, biomarkers that accurately predict the presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076a86ba587acca852618eb0571a6620
https://pubmed.ncbi.nlm.nih.gov/35537078
https://pubmed.ncbi.nlm.nih.gov/35537078
Autor:
Ymke van der Pol, Norbert Moldovan, Sandra Verkuijlen, Jip Ramaker, Dries Boers, Wendy Onstenk, Johan de Rooij, Idris Bahce, D. Michiel Pegtel, Florent Mouliere
Assays that account for the biological properties and fragmentation of cell-free DNA (cfDNA) can improve the performance of liquid biopsy. However, pre-analytic and physiological differences between individuals on fragmentomic analysis are poorly def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7dcd3509f0c009e1207ea5eb7e31d44
https://doi.org/10.1101/2021.09.17.460828
https://doi.org/10.1101/2021.09.17.460828