Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jiongwen Ou"'
Autor:
Daniele Novarina, Ridhdhi Desai, Jessica A. Vaisica, Jiongwen Ou, Mohammed Bellaoui, Grant W. Brown, Michael Chang
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1853-1867 (2020)
Homologous recombination is an important mechanism for genome integrity maintenance, and several homologous recombination genes are mutated in various cancers and cancer-prone syndromes. However, since in some cases homologous recombination can lead
Externí odkaz:
https://doaj.org/article/9cfbe17598654184abc2ae3e4e6d0ac7
Autor:
Mohammed Bellaoui, Grant W. Brown, Jiongwen Ou, Michael Chang, Ridhdhi Desai, Jessica A. Vaisica, Daniele Novarina
Publikováno v:
G3 : Genes, Genomes, Genetics, 10(6), 1858-1867. GENETICS SOCIETY AMERICA
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1853-1867 (2020)
G3: Genes|Genomes|Genetics
G3: Genes, Genomes, Genetics, Vol 10, Iss 6, Pp 1853-1867 (2020)
G3: Genes|Genomes|Genetics
Homologous recombination is an important mechanism for genome integrity maintenance, and several homologous recombination genes are mutated in various cancers and cancer-prone syndromes. However, since in some cases homologous recombination can lead
Autor:
Jiongwen Ou, Melainia McClain, Jay R. Unruh, Godai Suzuki, Won-Ki Huh, Sue L. Jaspersen, Zulin Yu, Tina L. Sing, Jesse Marshall-Sheppard, Michael Costanzo, Yoshikazu Ohya, Shinsuke Ohnuki, Bryan-Joseph San Luis, Charles Boone, Minnie P. Hung, Grant W. Brown
Publikováno v:
The Journal of Cell Biology
Sing et al. characterize an unanticipated role for the Saccharomyces cerevisiae RSC complex in ploidy maintenance. They show that RSC promotes the distribution of Nbp1 and Ndc1 to the spindle pole body (SPB) to facilitate SPB maturation and accurate
Autor:
Sarah Meister, James E. Haber, Jiongwen Ou, TaeHyung Kim, Zhaolei Zhang, Grant W. Brown, Askar Yimit, Ranjith P. Anand
Publikováno v:
Genetics. 203(1)
Double-strand DNA breaks occur upon exposure of cells to ionizing radiation and certain chemical agents or indirectly through replication fork collapse at DNA damage sites. If left unrepaired, double-strand breaks can cause genome instability and cel
Autor:
Sarah Meister, Askar Yimit, Ranjith P. Anand, Zhaolei Zhang, James E. Haber, TaeHyung Kim, Jiongwen Ou, Grant W. Brown
Double-strand DNA breaks occur upon exposure of cells to agents such as ionizing radiation and ultraviolet light or indirectly through replication fork collapse at DNA damage sites. If left unrepaired double-strand breaks can cause genome instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b1de7b67b0dfd873f985d8a7583372
https://doi.org/10.1101/032581
https://doi.org/10.1101/032581
Publikováno v:
Journal of Biological Chemistry. 285:21426-21436
Human topoisomerase IIIalpha is a type IA DNA topoisomerase that functions with BLM and RMI1 to resolve DNA replication and recombination intermediates. BLM, human topoisomerase IIIalpha, and RMI1 catalyze the dissolution of double Holliday junctions
Autor:
Chang Xu, Csanád Z. Bachrati, Leonard Wu, Michael Chang, Jiongwen Ou, Ian D. Hickson, Lei Li, Grant W. Brown, Weidong Wang, Jinhu Yin
Publikováno v:
Proceedings of the National Academy of Sciences. 103:4068-4073
BLM encodes a member of the highly conserved RecQ DNA helicase family, which is essential for the maintenance of genome stability. Homozygous inactivation of BLM gives rise to the cancer predisposition disorder Bloom’s syndrome. A common feature of
Publikováno v:
Genomics. 70:375-380
Genes coding for zinc-finger proteins constitute about 1% of the mammalian genome. Here we report the cloning of a novel mouse gene (Zfp319) encoding a nuclear protein with 11 zinc-finger motifs of the C2H2 type. Zfp319 consists of two exons, the sec
Publikováno v:
Journal of Biological Chemistry. 275:39237-39245
Transforming growth factor-beta1 (TGFbeta) is a strong activator of extracellular matrix accumulation. TGFbeta stimulates the gene coding for human alpha2(I)-collagen (COL1A2) by inducing binding of an Sp1-containing complex to an upstream promoter e
Autor:
Yong Lu, Jiongwen Ou, Edith Cheng, Anastasia Baryshnikova, Grant W. Brown, Jessica A. Vaisica, Frederick P. Roth
Genetic screens of the collection of ∼4500 deletion mutants in Saccharomyces cerevisiae have identified the cohort of nonessential genes that promote maintenance of genome integrity. Here we probe the role of essential genes needed for genome stabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c82f71d6a56eea22d5f7698b967421
https://europepmc.org/articles/PMC3430531/
https://europepmc.org/articles/PMC3430531/