Výsledky vyhledávání - "Jiongbo Liao"

Akademický článek

Menopausal Status Combined with Serum CA125 Level Significantly Predicted Concurrent Endometrial Cancer in Women Diagnosed with Atypical Endometrial Hyperplasia before Surgery †

Autor: Yaochen Lou, Jiongbo Liao, Weiwei Shan, Zhiying Xu, Xiaojun Chen, Jun Guan

Publikováno v: Diagnostics, Vol 12, Iss 1, p 6 (2021)

About 10–66% of patients with atypical endometrial hyperplasia diagnosed before surgery (preoperative-AEH) are found to have concurrent endometrial cancer (EC) at definitive hysterectomy, leading to incomplete primary surgery and delayed adjuvant t

Externí odkaz: https://doaj.org/article/43852792d1cc454daec0c18b0c051635

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Data from SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1α–Dependent Glycolysis

Autor: Yiwei Chu, Xi Chen, Jiongbo Liao, Yun Lu, Huanrong Liu, Xiao Wang, Yan Zhang, Hui Yang, Bo Shen, Yujing Bi, Guangwei Liu

Myeloid-derived suppressor cells (MDSC) display an immature phenotype that may assume a classically activated (M1) or alternatively activated phenotype (M2) in tumors. In this study, we investigated metabolic mechanisms underlying the differentiation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9673253860b00d444806d1e26ab57be4
https://doi.org/10.1158/0008-5472.c.6505866

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Supplementary Figures 1 - 13 from SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1α–Dependent Glycolysis

Autor: Yiwei Chu, Xi Chen, Jiongbo Liao, Yun Lu, Huanrong Liu, Xiao Wang, Yan Zhang, Hui Yang, Bo Shen, Yujing Bi, Guangwei Liu

PDF file - 436K, Fig.S1. MDSC polarizing differentiation condition alters glycolytic activity. Fig.S2.MDSC SIRT1 expansions in spleen and tumor of SIRT1KO and WT-bearing tumor mice. Fig.S3.SIRT1 deficiency MDSCs showed normal cell death and prolifera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ca90fb1def505c7b4ca4c5f6b8203c
https://doi.org/10.1158/0008-5472.22401441

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Comparison of the effect of oral megestrol acetate with or without levonorgestrel-intrauterine system on fertility-preserving treatment in patients with early-stage endometrial cancer: a prospective, open-label, randomized controlled phase II trial (ClinicalTrials.gov NCT03241914)

Autor: Zhiying Xu, Bingyi Yang, Jun Guan, Weiwei Shan, Jiongbo Liao, Wenyu Shao, Xiaojun Chen

Publikováno v: Journal of gynecologic oncology.

To evaluate the effect of levonorgestrel-releasing intrauterine system (LNG-IUS) plus oral megestrol acetate (MA) as fertility-preserving treatment in patients with early-stage endometrial cancer (EEC).In this single-center, phase II study with open-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7705838158e2d4a757779567b93796d8
https://pubmed.ncbi.nlm.nih.gov/36562136

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Verteporfin induced SUMOylation of YAP1 in endometrial cancer

Autor: Bo, Wang, Wenyu, Shao, Yue, Shi, Jiongbo, Liao, Xiaojun, Chen, Chao, Wang

Publikováno v: Am J Cancer Res

Yes-associated protein (YAP or YAP1) has been proposed to function as an oncogene in most cancers, with nuclear localization of YAP1 correlating with poor prognosis. Photosensitizer Verteporfin has been proven as an inhibitor of YAP1 through preventi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::299e5f1f0b29b3cb152e30a443a08040
https://pubmed.ncbi.nlm.nih.gov/32368396

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mTOR limits the recruitment of CD11b+Gr1+Ly6Chigh myeloid-derived suppressor cells in protecting against murine immunological hepatic injury

Autor: Zhengguo Zhang, Jiongbo Liao, Yiwei Chu, Yun Lu, Yujing Bi, Huanrong Liu, Shan Yang, Xi Chen, Ruifu Yang, Yan Zhang, Hui Yang, Guangwei Liu

Publikováno v: Journal of Leukocyte Biology. 95:961-970

The mTOR pathway integrates diverse environmental inputs, including immune signals and metabolic cues, to direct the innate and adaptive immune responses. MDSCs are a heterogeneous cell population that plays a crucial regulatory effect in immune-rela

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28cac26fe85a15834ffd6235fef6c68
https://doi.org/10.1189/jlb.0913473

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SIRT1 Limits the Function and Fate of Myeloid-Derived Suppressor Cells in Tumors by Orchestrating HIF-1α–Dependent Glycolysis

Autor: Yujing Bi, Yiwei Chu, Yun Lu, Xi Chen, Huanrong Liu, Xiao Wang, Bo Shen, Hui Yang, Yan Zhang, Guangwei Liu, Jiongbo Liao

Publikováno v: Cancer Research. 74:727-737

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262a953ba9870b3ee3c4eb99b8ccbb9c
https://doi.org/10.1158/0008-5472.can-13-2584

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The Calcineurin-NFAT Axis Controls Allograft Immunity in Myeloid-Derived Suppressor Cells through Reprogramming T Cell Differentiation

Autor: Xiao Wang, Yun Lu, Hui Yang, Lixiang Xue, Yujing Bi, Jiongbo Liao, Jian Wang, Guangwei Liu, Zhengguo Zhang, Xi Chen, Huanrong Liu

While cyclosporine (CsA) inhibits calcineurin and is highly effective in prolonging rejection for transplantation patients, the immunological mechanisms remain unknown. Herein, the role of calcineurin signaling was investigated in a mouse allogeneic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f86c05b4592498a8936b5b8b7ec857
https://europepmc.org/articles/PMC4285420/

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