Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jinzhang, Chen"'
Autor:
Li Xu, Jinzhang Chen, Chang Liu, Xiaoling Song, Yanqiao Zhang, Haitao Zhao, Sheng Yan, Weidong Jia, Zheng Wu, Yabing Guo, Jiayin Yang, Wei Gong, Yue Ma, Xiaobo Yang, Zhenzhen Gao, Nu Zhang, Xin Zheng, Mengyu Li, Dan Su, Minshan Chen
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Lenvatinib is widely used in treatment of unresectable hepatocellular carcinoma (uHCC), but the benefit of its combination with immunotherapy needs to be verified. This study evaluated the efficacy and safety of tislelizumab plus
Externí odkaz:
https://doaj.org/article/c3ae2efaf43843d5896283b1c2eb7e47
Autor:
Wei Zhu, Zhiming Zhang, Jinzhang Chen, Xiaolan Chen, Lei Huang, Xiaoyong Zhang, Xuan Huang, Na Ma, Weikang Xu, Xuan Yi, Xinyu Lu, Xin Fu, Siwei Li, Guoheng Mo, Yiyue Wang, Guosheng Yuan, Mengya Zang, Qi Li, Xiaotao Jiang, Yajing He, Sha Wu, Yukai He, Yongyin Li, Jinlin Hou
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Strategies to improve T cell therapy efficacy in solid tumors such as hepatocellular carcinoma (HCC) are urgently needed. The common cytokine receptor γ chain (γc) family cytokines such as IL-2, IL-7, IL-15 and IL-21 play fundamental roles
Externí odkaz:
https://doaj.org/article/25b1939bfa5d4053805ba1ed9abc91df
Autor:
Guosheng Yuan, Wenli Li, Mengya Zang, Rong Li, Qi Li, Xiaoyun Hu, Qi Zhang, Wei Huang, Jian Ruan, Huajin Pang, Jinzhang Chen
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Objectives To explore the efficacy and safety of Transarterial chemoembolization (TACE) in combination with immune checkpoint inhibitors (ICIs) and tyrosine kinase inhibitors (TKIs) in patients with unresectable hepatocellular carcinoma (uHC
Externí odkaz:
https://doaj.org/article/b6c77012015a455282b94e93a668e7c9
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)
Key points Baseline HBV loads do not affect the prognosis of HCC patients receiving anti-PD-1 in combination with antiangiogenic therapy. Besides, PD-1 inhibitors do not aggravate HBV reactivation and hepatic impairment undergoing concurrent TAF prop
Externí odkaz:
https://doaj.org/article/f2cb7053080949dc87d5066299cb2822
Autor:
Yifei Shen, Shuaishuai Xu, Chanqi Ye, Qiong Li, Ruyin Chen, Wei Wu, Qi Jiang, Yunlu Jia, Xiaochen Zhang, Longjiang Fan, Wenguang Fu, Ming Jiang, Jinzhang Chen, Michael P. Timko, Peng Zhao, Jian Ruan
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106003- (2023)
Summary: Despite the epidemiological association between intrahepatic cholangiocarcinoma (ICC) and hepatitis B virus (HBV) infection, little is known about the relevant oncogenic effects. A cohort of 32 HBV-infected ICC and 89 non-HBV-ICC patients we
Externí odkaz:
https://doaj.org/article/1a615caec7e04e8a98c1db621b3351eb
Autor:
Changqie Pan, Jianhua Wu, Siting Zheng, Huiying Sun, Yisheng Fang, Zhenhua Huang, Min Shi, Li Liang, Jianping Bin, Yulin Liao, Jinzhang Chen, Wangjun Liao
Publikováno v:
Cancer Communications, Vol 41, Iss 10, Pp 1049-1070 (2021)
Abstract Background Depression is a common, easily ignored, accompanied disease of gastric cancer (GC) patients and is often observed with elevated plasma catecholamine levels. Depression frequently promotes GC progression and leads to poor clinical
Externí odkaz:
https://doaj.org/article/ff18b05c8c4e4e69872fc5348abb67d9
Autor:
Guosheng Yuan, Fuli Xie, Yangda Song, Qi Li, Rong Li, Xiaoyun Hu, Mengya Zang, Xiao Cheng, Guanting Lu, Jing Huang, Wenzhe Fan, Xiaoxiang Rong, Jian Sun, Jinzhang Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe clinical significance of liver stiffness (LS) measured by shear wave elastography (SWE) in programmed cell death protein-1 (PD-1) inhibitors treated advanced hepatocellular carcinoma (HCC) patients remains unknown. This study aimed to e
Externí odkaz:
https://doaj.org/article/dd5f5974fe4749bd905cfb7133f4038f
Publikováno v:
Annals of Medicine, Vol 53, Iss 1, Pp 437-447 (2021)
AbstractPurpose Hepatocellular carcinoma (HCC) is refractory cancer with high morbidity and high mortality. DEAH-box polypeptide 32 (DHX32) was upregulated in several types of malignancies and predicted poor prognosis. Herein, we investigated the rol
Externí odkaz:
https://doaj.org/article/6a7c140c8f3b49fc8889e47ea6ed97ef
Autor:
Qi Li, Mengran Cao, Guosheng Yuan, Xiao Cheng, Mengya Zang, Ming Chen, Xiaoyun Hu, Jing Huang, Rong Li, Yabing Guo, Jian Ruan, Jinzhang Chen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCombining an antiangiogenic agent with an anti-PD-1 agent is a promising strategy for unresectable hepatocellular carcinoma (HCC).AimsTo explore the effectiveness and tolerability of lenvatinib plus camrelizumab vs. lenvatinib monotherapy a
Externí odkaz:
https://doaj.org/article/c6a2dd20c06b462f8a052f55f10684b3
Autor:
Jinzhang Chen, Xiaoxiang Rong, Xinhui Liu, Dayong Zheng, Xiaodong Rong, Fengsheng Chen, Peng Zhao, Feiye Liu, Jian Ruan
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Forkhead box C2 (FOXC2) is a crucial factor involving in various cancers. However, its functions in hepatocellular carcinoma (HCC) is unknown. Here, we explored the role of FOXC2 in the progression of HCC and its potential mechani
Externí odkaz:
https://doaj.org/article/4b62dd900bda44678c96305759264790