Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jinze Shen"'
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Background Alternative splicing of pre‐mRNA is a fundamental regulatory process in multicellular eukaryotes, significantly contributing to the diversification of the human proteome. RNA‐binding fox‐1 homologue 2 (RBFOX2), a member of t
Externí odkaz:
https://doaj.org/article/569acc94f07f4c868e665d0e56d13b4f
Exploring the multifaceted role of GCN1: Implications in cellular responses and disease pathogenesis
Autor:
Xinying Zheng, Jinze Shen, Hongting Jiang, Mei Tian, Qurui Wang, Kailin Guo, Ruixiu Chen, Qing Xia, Qibin Yan, Lihua Du, Shiwei Duan
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116681- (2024)
GCN1 is a highly conserved protein present widely across eukaryotes. As an upstream activator of protein kinase GCN2, GCN1 plays a pivotal role in integrated stress responses, such as amino acid starvation and oxidative stress. Through interaction wi
Externí odkaz:
https://doaj.org/article/6b7b1923ac36428e9bb0820f897650b8
Autor:
Jiejie Guo, Mei Tian, Yongang Li, Yitong Guo, Ting Zhang, Xuan Liu, Jinze Shen, Lin Zhang, Yueqi Yu, Ling Cao, Haiyan Gu, Yanfang Li, Shiwei Duan, Qinwen Wang
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-19 (2024)
Abstract Background Stroke stands as the second leading cause of death worldwide. Currently, extensive research has been conducted on stroke risk factors. However, when stroke patients contend with multiple risk factors, the impact on clinical indica
Externí odkaz:
https://doaj.org/article/e65cec5cb0fc488db79331f3da99f528
Autor:
Jinze Shen, Xinming Su, Ming Pan, Zehua Wang, Yufei Ke, Qurui Wang, Jingyin Dong, Shiwei Duan
Publikováno v:
Cancer Innovation, Vol 2, Iss 6, Pp 448-462 (2023)
Abstract Long noncoding RNAs (lncRNAs) are a class of nonprotein‐coding transcripts that are longer than 200 nucleotides. LINC00355 is a lncRNA located on chromosome 13q21.31 and is consistently upregulated in various cancers. It regulates the expr
Externí odkaz:
https://doaj.org/article/79b94a1588464b959cd5fc062f753562
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
tRNA-derived small RNAs (tsRNAs) are novel small non-coding RNAs originating from mature or precursor tRNAs (pre-tRNA), typically spanning 14 to 30 nt. The Mitogen-activated protein kinases (MAPK) pathway orchestrates cellular responses, influencing
Externí odkaz:
https://doaj.org/article/7d5fa20e4581402da574b11fe47dab4d
Autor:
Qing Xia, Qibin Yan, Zehua Wang, Qinyuan Huang, Xinying Zheng, Jinze Shen, Lihua Du, Hanbing Li, Shiwei Duan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Disulfidptosis is a newly discovered mode of cell death. However, its relationship with breast cancer subtypes remains unclear. In this study, we aimed to construct a disulfidptosis-associated breast cancer subtype prediction model. We obtai
Externí odkaz:
https://doaj.org/article/3760c1533fdf47519e74ce00740ed4ce
Publikováno v:
Journal of Bio-X Research, Vol 7 (2024)
DDX21 belongs to the DEAD-box (DDX) family of helicases but deviates from the characteristic sequence Asp–Glu–Ala–Asp (DEAD) to Asp–Glu–Val–Asp. In addition to the typical helicase activity associated with the DEAD-box family, DDX21 also
Externí odkaz:
https://doaj.org/article/0ba5ae6dc92b47399c651249ea656440
Autor:
Qing Xia, Jinze Shen, Qurui Wang, Ruixiu Chen, Xinying Zheng, Qibin Yan, Lihua Du, Hanbing Li, Shiwei Duan
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0299138 (2024)
BackgroundCuproptosis is a novel copper-dependent mode of cell death that has recently been discovered. The relationship between Cuproptosis-related ncRNAs and breast cancer subtypes, however, remains to be studied.MethodsThe aim of this study was to
Externí odkaz:
https://doaj.org/article/1451be1fa9704135b4f84fa62acede34
Autor:
Jinze Shen, Chenhao Liang, Xinming Su, Qurui Wang, Yufei Ke, Jie Fang, Dayong Zhang, Shiwei Duan
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract MicroRNAs (miRNAs) are a class of small non-coding RNAs ranging from 17 to 25 nt in length. miR-637 is down-regulated in most cancers and up-regulated only in clear cell renal cell carcinoma (ccRCC). miR-637 can target 21 protein-coding gene
Externí odkaz:
https://doaj.org/article/4308dbb38da5488d885dbfadc1051cc2
Publikováno v:
MedComm, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Tumor suppressor p53 can transcriptionally activate downstream genes in response to stress, and then regulate the cell cycle, DNA repair, metabolism, angiogenesis, apoptosis, and other biological responses. p53 has seven functional domains a
Externí odkaz:
https://doaj.org/article/0dc5f0c5b5c643e4a82f5b989ec38e02