Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jinyuan Xiao"'
Autor:
Qiuxia Wei, Ruizhi Chen, Xue He, Yanan Qu, Changjian Yan, Xiaoni Liu, Jing Liu, Jiahao Luo, Zining Yu, Wenping Hu, Liqun Wang, Xiaoya Lin, Chaoling Wu, Jinyuan Xiao, Haibo Zhou, Jing Wang, Mingxia Zhu, Ping Yang, Yingtong Chen, Qilong Tan, Xiaoliang Yuan, Hongmei Jing, Weilong Zhang
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-16 (2024)
Abstract Cellular senescence (CS) is closely related to tumor progression. However, the studies about CS genes across human cancers have not explored the relationship between cancer senescence signature and telomere length. Additionally, single-cell
Externí odkaz:
https://doaj.org/article/a1df8d8e037f46b8905fb1d9ac4e3b5f
Autor:
Yongfeng Bi, Dong Wan, Si Chen, Huafei Chen, Lingchuan Guo, Xiaoshun He, Rong Rong, Jinyuan Xiao, Wei Gao, Sheng Xiao
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Giant cell glioblastoma often exhibits genome instability and is frequently associated with mutations in genes involved in DNA repair pathways including TP53 and DNA mismatch repair genes. Several germline mutations have been identified in giant cell
Externí odkaz:
https://doaj.org/article/f19cc88deb344cccb44be3e5a6c75a9b
Autor:
Haitao Huang, Na Li, Yingkuan Liang, Rutao Li, Xing Tong, Jinyuan Xiao, Hongzhen Tang, Dong Jiang, Kai Xie, Chen Fang, Shaomu Chen, Guangbin Li, Bin Wang, Jiaqian Wang, Haitao Luo, Lingchuan Guo, Haitao Ma, Wei Jiang, Yu Feng
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 11, Pp n/a-n/a (2023)
Abstract Background Biopsies obtained from primary oesophageal squamous cell carcinoma (ESCC) guide diagnosis and treatment. However, spatial intra‐tumoral heterogeneity (ITH) influences biopsy‐derived information and patient responsiveness to th
Externí odkaz:
https://doaj.org/article/1453d8813e374a2f9260060233cc5e30
Autor:
Shifen Zhang, Na Li, Feifei Wang, Hailing Liu, Yuhan Zhang, Jinyuan Xiao, Weihao Qiu, Ceng Zhang, Xinjuan Fan, Mingxin Qiu, Mingzhou Li, Hongzhen Tang, Shiheng Fan, Jiaqian Wang, Haitao Luo, Xiangzhao Li, Jie Lin, Yan Huang, Li Liang
Publikováno v:
Pharmacological Research, Vol 197, Iss , Pp 106974- (2023)
Neoadjuvant chemoradiotherapy (nCRT) has become the standard treatment for patients with locally advanced rectal cancer (LARC). However, 20–40% of patients with LARC show little to no response to nCRT. Thus, comprehensively understanding the tumor
Externí odkaz:
https://doaj.org/article/ba263d87e38a4c5cba5115a034216846
Autor:
Yang Zhang, Yan Huang, Li Zhang, Jie Sun, Hongyun Zhao, Yunpeng Yang, Wenfeng Fang, Yuanyuan Zhao, Yuxiang Ma, Qun Li, Ye Guo, Yuhan Zhang, Jinhui Xue, Xiaoxiao Ge, Bangyong Zhang, Jinyuan Xiao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background KN046 is a novel bispecific antibody targeting programmed death ligand 1 (PD-L1) and cytotoxic T lymphocyte-associated protein 4 (CTLA-4). This multicenter phase I trial investigated the safety, tolerability, pharmacokinetics (PK), and eff
Externí odkaz:
https://doaj.org/article/95d8c6373ec04b3a82fc11ecb0923947
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3567-3580 (2022)
Codon optimality has been demonstrated to be an important determinant of mRNA stability and expression levels in multiple model organisms and human cell lines. However, tissue-specific codon optimality has not been developed to investigate how codon
Externí odkaz:
https://doaj.org/article/23f02b88b5004a5185dfcf25b6b675f9
Autor:
Xiaofan Su, Haoxuan Jin, Ning Du, Jiaqian Wang, Huiping Lu, Jinyuan Xiao, Xiaoting Li, Jian Yi, Tiantian Gu, Xu Dan, Zhibo Gao, Manxiang Li
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundImmune checkpoint inhibitors (ICIs) induce durable responses, but only a minority of patients achieve clinical benefits. The development of gene expression profiling of tumor transcriptomes has enabled identifying prognostic gene expression
Externí odkaz:
https://doaj.org/article/0ed31e7d09864ad38d5f25e4232f90df
Autor:
Xia Ran, Jinyuan Xiao, Yi Zhang, Huajing Teng, Fang Cheng, Huiqian Chen, Kaifan Zhang, Zhongsheng Sun
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Intratumor heterogeneity (ITH) has been shown to be inversely associated with immune infiltration in several cancers including clear cell renal cell carcinoma (ccRCC), but it remains unclear whether ITH is associated with response to immu
Externí odkaz:
https://doaj.org/article/fc7fcd309d944cdb9962de8343ccdaef
Autor:
Kaifan Zhang, Yi Zhang, Jinyuan Xiao, Zhong Sheng Sun, Xia Ran, Huiqian Chen, Fang Cheng, Huajing Teng
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology
Background: Intratumor heterogeneity (ITH) has been shown to be inversely associated with immune infiltration in several cancers including clear cell renal cell carcinoma (ccRCC), but it remains unclear whether ITH is associated with response to immu