A deep learning model for differentiating paediatric intracranial germ cell tumour subtypes and predicting survival with MRI: a multicentre prospective study

Autor: Yanong Li, Zhizheng Zhuo, Jinyuan Weng, Sven Haller, Harrison X. Bai, Bo Li, Xing Liu, Mingwang Zhu, Zheng Wang, Jane Li, Xiaoguang Qiu, Yaou Liu

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)

Abstract Background The pretherapeutic differentiation of subtypes of primary intracranial germ cell tumours (iGCTs), including germinomas (GEs) and nongerminomatous germ cell tumours (NGGCTs), is essential for clinical practice because of distinct t

Externí odkaz: https://doaj.org/article/c5dba6b6421f41d099609d8dcd4cd1b0

Deep Learning for Noninvasive Assessment of H3 K27M Mutation Status in Diffuse Midline Gliomas Using MR Imaging

Autor: Junjie Li, Peng Zhang, Liying Qu, Ting Sun, Yunyun Duan, Minghao Wu, Jinyuan Weng, Zhaohui Li, Xiaodong Gong, Xing Liu, Yongzhi Wang, Wenqing Jia, Xiaorui Su, Qiang Yue, Jianrui Li, Zhiqiang Zhang, Frederik Barkhof, Raymond Y. Huang, Ken Chang, Haris Sair, Chuyang Ye, Liwei Zhang, Zhizheng Zhuo, Yaou Liu

Publikováno v: Journal of Magnetic Resonance Imaging. John Wiley and Sons Inc.
Li, J, Zhang, P, Qu, L, Sun, T, Duan, Y, Wu, M, Weng, J, Li, Z, Gong, X, Liu, X, Wang, Y, Jia, W, Su, X, Yue, Q, Li, J, Zhang, Z, Barkhof, F, Huang, R Y, Chang, K, Sair, H, Ye, C, Zhang, L, Zhuo, Z & Liu, Y 2023, ' Deep Learning for Noninvasive Assessment of H3 K27M Mutation Status in Diffuse Midline Gliomas Using MR Imaging ', Journal of Magnetic Resonance Imaging . https://doi.org/10.1002/jmri.28606

Background: Determination of H3 K27M mutation in diffuse midline glioma (DMG) is key for prognostic assessment and stratifying patient subgroups for clinical trials. MRI can noninvasively depict morphological and metabolic characteristics of H3 K27M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efbcfcaee75f0b0a9cb09efea05be05
https://doi.org/10.1002/jmri.28606