Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Jinyu HU"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Sunitinib, a newly developed multi-targeted tyrosine kinase inhibitor (TKI), has become a common therapeutic option for managing advanced renal cell carcinoma (RCC). Examining the mechanism underlying the interaction between sunit
Externí odkaz:
https://doaj.org/article/88eb762f5aae4fe0a0f8b15f1fd87a9c
Publikováno v:
Journal of Asian Architecture and Building Engineering, Vol 23, Iss 5, Pp 1776-1795 (2024)
Urban green spaces exert beneficial effects on both individuals and communities. However, as urban sprawl intensifies, socioeconomic disparities widen, and populations burgeon, the concepts of green fairness and environmental justice confront substan
Externí odkaz:
https://doaj.org/article/20d512ae36324325aff96768095692fa
Publikováno v:
Zhongguo gonggong weisheng, Vol 40, Iss 8, Pp 926-930 (2024)
ObjectiveTo explore the relationship between different dietary patterns and internal exposure levels of cadmium and lead among middle-aged and elderly populations in cadmium-polluted areas, and to provide a scientific basis for adopting reasonable di
Externí odkaz:
https://doaj.org/article/05eab465a44a403bb7ce35696f21a289
Autor:
Jie Chen, Yingying Hu, Jinyu Hu, Zhize Ye, Qianmeng Lin, Jian-ping Cai, Guo-xin Hu, Ren-ai Xu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117511- (2024)
The aim of this study was to investigate the catalytic activity of 26 Cytochrome P450 3A4 (CYP3A4) variants and drug interactions on imatinib metabolism in recombinant insect microsomes. This study was designed with an appropriate incubation system a
Externí odkaz:
https://doaj.org/article/3cef741ee9d0453fa4742ed7da321f06
Autor:
Zhize Ye, Hailun Xia, Jinyu Hu, Ya-nan Liu, Anzhou Wang, Jian-ping Cai, Guo-xin Hu, Ren-ai Xu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116421- (2024)
Tofacitinib can effectively improve the clinical symptoms of rheumatoid arthritis (RA) patients. In this current study, a recombinant human CYP2C19 and CYP3A4 system was operated to study the effects of recombinant variants on tofacitinib metabolism.
Externí odkaz:
https://doaj.org/article/e521898341db4c25ac01509310f911d0
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-7 (2024)
Abstract Broad-spectrum histone deacetylase inhibitors (HDACi) have excellent anti-tumor effects, such as abexinostat, which was a novel oral HDACi that was widely used in clinical treatment. The purpose of this study was to establish a rapid and rel
Externí odkaz:
https://doaj.org/article/cba831056b9147dfa28b4d137c1d0d4d
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundEpidemiologic and observational data have found a risk association between thyroid dysfunction and cutaneous malignant melanoma (CMM), however, the cause and direction of these effects are yet unknown. By using a bidirectional two-sample Me
Externí odkaz:
https://doaj.org/article/cb39d4f000e24d168dbeacfe20780653
Autor:
Jingjing Zhang, Fengting Liu, Yaran Suo, Dudu Tong, Jinyu Hu, Hai‐Ning Lyu, Jingjing Liao, Jiaqi Wang, Jigang Wang, Chengchao Xu
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 9, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/52ff70f320694f87a0f2027e28b7bb39
Publikováno v:
Remote Sensing, Vol 15, Iss 19, p 4688 (2023)
Deep learning (DL) algorithms have demonstrated important breakthroughs for hyperspectral image (HSI) classification. Despite the remarkable success of DL, the burden of a manually designed DL structure with increased depth and size aroused the diffi
Externí odkaz:
https://doaj.org/article/57a6de5d6f364c30b0475345fdb42a2b
Publikováno v:
Journal of the American Society for Horticultural Science, Vol 147, Iss 2, Pp 73-81 (2022)
The spicas of Prunella vulgaris are widely used in the medical, beverage, and ornamental fields. Temperature and photoperiod are the two main ecological factors that determine the transformation of many plants from vegetative growth to reproductive g
Externí odkaz:
https://doaj.org/article/d7742532ad2941a797d9312102a0c10e