Zobrazeno 1 - 10
of 339
pro vyhledávání: '"Jinyong Peng"'
Publikováno v:
Redox Biology, Vol 73, Iss , Pp 103175- (2024)
Exploring and discovering novel circRNAs is one of the ways to develop innovative drugs for the diagnosis and treatment of myocardial ischemia-reperfusion injury (MI/RI). In the work, some dysregulated circRNAs were found by microarray screening anal
Externí odkaz:
https://doaj.org/article/6f9d45dd1e85432b9e4cd4650a686641
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116529- (2024)
Myocardial infarction (MI) is the primary cause of cardiac mortality. Esculentoside A (EsA), a triterpenoid saponin, has anti-inflammatory and antioxidant activities. However, its effect on MI remains unknown. In this study, the protective effect and
Externí odkaz:
https://doaj.org/article/7141fc34d9f343bc811c2f87b9771e6c
Autor:
Zhang Mao, Haochen Hui, Xuerong Zhao, Lina Xu, Yan Qi, Lianhong Yin, Liping Qu, Lan Han, Jinyong Peng
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 10, Pp 1153-1167 (2023)
It is necessary to explore potent therapeutic agents via regulating gut microbiota and metabolism to combat Parkinson's disease (PD). Dioscin, a bioactive steroidal saponin, shows various activities. However, its effects and mechanisms against PD are
Externí odkaz:
https://doaj.org/article/1fe3b8f4255b47409a8dbb5f0d1c50f2
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 7, Pp 760-775 (2023)
Nine major cell populations among 46,716 cells were identified in mouse intestinal ischemia‒reperfusion (II/R) injury by single-cell RNA sequencing. For enterocyte cells, 11 subclusters were found, in which enterocyte cluster 1 (EC1), enterocyte cl
Externí odkaz:
https://doaj.org/article/07aa2818005c43ba85cfbc7e75e354d3
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106925- (2023)
With changing lifestyles, non-alcoholic fatty liver disease (NAFLD) has become the most prevalent liver disease worldwide. A substantial increase in the incidence, mortality, and associated burden of NAFLD-related advanced liver disease is expected.
Externí odkaz:
https://doaj.org/article/50d4b877afd84d16a8baad80a52c4fed
Autor:
Xufeng Tao, Yan Qi, Lina Xu, Lianhong Yin, Xu Han, Youwei Xu, Changyuan Wang, Huijun Sun, Jinyong Peng
Publikováno v:
Pharmacological Research, Vol 195, Iss , Pp 106894- (2023)
Externí odkaz:
https://doaj.org/article/d6711e3cc1b44ff6a8dd8fbc93cfa7c6
Autor:
Meng Qi, Lingli Zheng, Yan Qi, Xu Han, Youwei Xu, Lina Xu, Lianhong Yin, Changyuan Wang, Yanyan Zhao, Huijun Sun, Kexin Liu, Jinyong Peng
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106744- (2023)
Externí odkaz:
https://doaj.org/article/ecdcb96671d34c559ab587944003a7e2
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 3150-3164 (2021)
The three-dimensional (3D) conformation of chromatin is integral to the precise regulation of gene expression. The 3D genome and genomic variations in non-alcoholic fatty liver disease (NAFLD) are largely unknown, despite their key roles in cellular
Externí odkaz:
https://doaj.org/article/6a39f2cff8ea4349a975e87949c8e339
Autor:
Yanna Zhu, Xiaokui Huo, Changyuan Wang, Qiang Meng, Zhihao Liu, Huijun Sun, Aiping Tan, Xiaodong Ma, Jinyong Peng, Kexin Liu
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 15, Iss 2, Pp 252-263 (2020)
This study aimed to clarify that organic anion transporters (OATs) mediate the drug–drug interaction (DDI) between imipenem and cilastatin. After co-administration with imipenem, the plasma concentrations and the plasma concentration-time curve (AU
Externí odkaz:
https://doaj.org/article/501cb48da2c749c78c55bb0f4e75ef11
Autor:
Shilei Yang, Zhihao Liu, Changyuan Wang, Shijie Wen, Qiang Meng, Xiaokui Huo, Huijun Sun, Xiaodong Ma, Jinyong Peng, Zhonggui He, Kexin Liu
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 14, Iss 6, Pp 677-686 (2019)
To assess the mechanism of the pharmacokinetic interaction between piperacillin and tazobactam, renal excretion and pharmacokinetic studies of piperacillin/tazobactam were investigated in normal and bacteremia rats. A bacteremia model was established
Externí odkaz:
https://doaj.org/article/8a1d5a9f17ac44eb99f0173f4d764cfd