Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jinying Piao"'
Autor:
Alkebaier Aobulikasimu, Tao Liu, Jinying Piao, Shingo Sato, Hiroki Ochi, Atsushi Okawa, Kunikazu Tsuji, Yoshinori Asou
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The mechanistic regulation of bone mass in aged animals is poorly understood. In this study, we examined the role of SIRT6, a longevity-associated factor, in osteocytes, using mice lacking Sirt6 in Dmp-1-expressing cells (cKO mice) and the M
Externí odkaz:
https://doaj.org/article/d194b5107db345eb9a57e9816ffdca71
Autor:
Yoshinori Asou, Munetaka Iwata, Hiroki Ochi, Maierhaba Ailixiding, Zulipiya Aibibula, Jinying Piao, Guangwen Jin, Yasushi Hara, Atsushi Okawa
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162794 (2016)
Obesity is a risk factor for osteoarthritis (OA). To investigate the roles of increased mechanical loading in the onset of obesity-induced OA, knee joints were histologically analyzed after applying a tail suspension (TS) model to a high-fat diet (HF
Externí odkaz:
https://doaj.org/article/ae4ad9eedb024bf083e024456218d938
Autor:
Makiko Iwasaki, Jinying Piao, Ayako Kimura, Shingo Sato, Hiroyuki Inose, Hiroki Ochi, Yoshinori Asou, Kenichi Shinomiya, Atsushi Okawa, Shu Takeda
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43372 (2012)
Ossification of the Posterior Longitudinal Ligament (OPLL) is a disease that is characterized by the ectopic calcification of the ligament; however, the pathogenesis of OPLL remains to be investigated. We attempted to identify the in vivo role of Run
Externí odkaz:
https://doaj.org/article/28646da4b893407c8592b40df09b02cf
Autor:
Alkebaier Aobulikasimu, Tao Liu, Jinying Piao, Shingo Sato, Hiroki Ochi, Atsushi Okawa, Kunikazu Tsuji, Yoshinori Asou
The mechanistic regulation of bone mass in aged animals is poorly understood. In this study, we examined the role of SIRT6, a longevity-associated factor, in osteocytes, using mice lacking Sirt6 in Dmp-1-expressing cells (cKO mice) and the MLO-Y4 ost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d079778b030115f48bf7129825caecea
https://doi.org/10.21203/rs.3.rs-1954276/v1
https://doi.org/10.21203/rs.3.rs-1954276/v1
Autor:
Takuya Oyaizu, Toshio Miyata, Yoshinori Asou, Yoichi Ezura, Aidehamu Aihemaiti, Kunikazu Tsuji, Naoki Yamamoto, Shingo Sato, Jinying Piao, Atsushi Okawa, Hiroki Ochi
Publikováno v:
Biochemical and biophysical research communications. 534
Sarcopenia is among the most common medical problems of the aging population worldwide and a major social concern. Here, we explored the therapeutic potential of TM5484, a novel orally available PAI-1 inhibitor, to prevent sarcopenia. The sarcopenic
Autor:
Tetsuo Nakabayashi, Guangwen Jin, Shingo Sato, Zulipiya Aibibula, Jinying Piao, Kunikazu Tsuji, Daisuke Koga, Toshio Miyata, Hiroki Ochi, Alkebaier Aobulikasimu, Atsushi Okawa, Yoshinori Asou
Publikováno v:
FEBS Open Bio
Osteoporosis is a progressive bone disease caused by an imbalance between bone resorption and formation. Recently, plasminogen activator inhibitor-1 (PAI-1) was shown to play an important role in bone metabolism using PAI-1-deficient mice. In this st
Autor:
Yasushi Hara, Jinying Piao, Daisuke Koga, Yoshinori Asou, Sadao Morita, Munetaka Iwata, Zulipiya Aibibula, Atsushi Okawa, Maierhaba Ailixiding
Publikováno v:
Biochemical and Biophysical Research Communications. 466(3):319-326
Osteoarthritis (OA) is a chronic degenerative joint disorder commonly associated with metabolic syndrome. As ageing and obesity has a great impact on the initiation/severity of OA, herein we sought to investigate the involvement of Sirt6 in the cross
Autor:
Jinying Piao1, Kunikazu Tsuji2, Hiroki Ochi3, Munetaka Iwata4, Daisuke Koga5, Atsushi Okawa5, Sadao Morita1, Shu Takeda6, Yoshinori Asou5 y.orth@tmd.ac.jp
Publikováno v:
Scientific Reports. 10/25/2013, p1-10. 10p.
Autor:
Yasushi Hara, Yoshinori Asou, Jinying Piao, Munetaka Iwata, Zulipiya Aibibula, Atsushi Okawa, Maierhaba Ailixiding
Publikováno v:
Biochemical and biophysical research communications. 472(1)
A metabolic syndrome (MetS) is accompanied by hyperuricemia, during which xanthine oxidoreductase (XOR) catalyzes the production of uric acid. In the cohort study, a correlation between uric acid concentration in the synovial fluid and osteoarthritis
Autor:
Maierhaba Ailixiding, Yasushi Hara, Yoshinori Asou, Munetaka Iwata, Zulipiya Aibibula, Guangwen Jin, Atsushi Okawa, Hiroki Ochi, Jinying Piao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 9, p e0162794 (2016)
PLoS ONE, Vol 11, Iss 9, p e0162794 (2016)
Obesity is a risk factor for osteoarthritis (OA). To investigate the roles of increased mechanical loading in the onset of obesity-induced OA, knee joints were histologically analyzed after applying a tail suspension (TS) model to a high-fat diet (HF