Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jinyang Zhen"'
Publikováno v:
Journal of Diabetes Investigation, Vol 13, Iss 4, Pp 696-705 (2022)
ABSTRACT Aims/Introduction To investigate the association of subtle alterations in thyroid function with presarcopenia among patients with type 2 diabetes mellitus. Materials and Methods A total of 1,865 adult patients with type 2 diabetes mellitus w
Externí odkaz:
https://doaj.org/article/5296d8d87b744c909984fc243a0d0a96
Autor:
Ying Yang, Hua Shu, Jingxin Hu, Lei Li, Jianyu Wang, Tingting Chen, Jinyang Zhen, Jinhong Sun, Wenli Feng, Yi Xiong, Yumeng Huang, Xin Li, Kai Zhang, Zhenqian Fan, Hui Guo, Ming Liu
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Preproinsulin (PPI) translocation across the membrane of the endoplasmic reticulum (ER) is the first and critical step of insulin biosynthesis. Inefficient PPI translocation caused by signal peptide (SP) mutations can lead to β-cell failure and diab
Externí odkaz:
https://doaj.org/article/f181a580e0754ad58bd5fd01e9edebaa
Autor:
Jing Yang, Jinyang Zhen, Wenli Feng, Zhenqian Fan, Li Ding, Xiaoyun Yang, Yumeng Huang, Hua Shu, Jing Xie, Xin Li, Jingting Qiao, Yuxin Fan, Jinhong Sun, Na Li, Tengli Liu, Shusen Wang, Xiaona Zhang, Peter Arvan, Ming Liu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(45)
Recessive mutations in IER3IP1 (immediate early response 3 interacting protein 1) cause a syndrome of microcephaly, epilepsy, and permanent neonatal diabetes (MEDS). IER3IP1 encodes an endoplasmic reticulum (ER) membrane protein, which is crucial for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bab309a9ebb352f9c3f6a034224ec6b
https://pubmed.ncbi.nlm.nih.gov/36322741
https://pubmed.ncbi.nlm.nih.gov/36322741
Autor:
Rui Liang, Jianyu Wang, Shusen Wang, Jing Yang, Ming Liu, Na Li, Jinyang Zhen, Yumeng Huang, Tengli Liu
Publikováno v:
European Journal of Endocrinology. 185:565-576
Objective Progressive beta-cell dysfunction is a hallmark of type 2 diabetes (T2D). Increasing evidence indicates that over-stimulating proinsulin synthesis causes proinsulin misfolding and impairs insulin maturation and storage in db/db mice. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0616614329f806f1d2e2e87ee1db0bc8
https://doi.org/10.1530/eje-21-0144
https://doi.org/10.1530/eje-21-0144
Autor:
SHUHUI JI, HUA SHU, WENLI FENG, JINYANG ZHEN, JINGTING QIAO, YADI HUANG, SHANSHAN CHEN, MING LIU
Publikováno v:
Diabetes. 71
Glucokinase (GCK) mainly exists in pancreatic β-cell, hepatocytes and brain, and is the first-rate limiting enzyme in glucose metabolism pathway. The heterozygous inactivation mutation of GCK leads to Maturity-onset diabetes of the young (MODY2) , a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85207e830609b333b8c982e5a60e8185
https://doi.org/10.2337/db22-317-or
https://doi.org/10.2337/db22-317-or
Autor:
JING YANG, JINYANG ZHEN, WENLI FENG, ZHENQIAN FAN, YUMENG HUANG, HUA SHU, XIN LI, JINGTING QIAO, YUXIN FAN, JINHONG SUN, NA LI, TENGLI LIU, SHUSEN WANG, XIAONA ZHANG, PETER ARVAN, MING LIU
Publikováno v:
Diabetes. 71
Recessive mutations in IER3IP1 (Immediate Early Response 3 Interacting Protein 1) cause a triad of microcephaly, epilepsy, and permanent neonatal diabetes syndrome (MEDS) . IER3IP1 encodes an endoplasmic reticulum (ER) membrane protein, which is cruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d23b2e7ebed4e22aa75da7ef7fc87829
https://doi.org/10.2337/db22-200-or
https://doi.org/10.2337/db22-200-or
Autor:
Yuting Li, Qinghua Wang, Xiaopan Gao, Jinyang Zheng, Wenjing Zhang, Yanfeng Ren, Wei Shen, Wei Su, Ping Lu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCurrently developed molecular markers can predict the effectiveness of cancer immunotherapy and screen beneficiaries to some extent, but they are not stable enough. Therefore, there is an urgent need for discovering novel biomarkers. At the
Externí odkaz:
https://doaj.org/article/7eae41302d2a47b0870fc08fb8fbcc12
Publikováno v:
Communications in Computer and Information Science ISBN: 9789811952081
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b40976cf5cc9b0de0591d29d6000e2
https://doi.org/10.1007/978-981-19-5209-8_9
https://doi.org/10.1007/978-981-19-5209-8_9
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background This study aimed to identify potential biomarkers for the diagnosis and treatment of osteoporosis (OP). Methods Data sets were downloaded from the Gene Expression Omnibus database, and differentially programmed cell death-related
Externí odkaz:
https://doaj.org/article/b2f7bc1052784ec3a16fd70205743fe8
Autor:
Jinfeng Zhu, Huifang Xiao, Chuntuan Li, Xiaofeng Li, Jinyang Zheng, Xihu Yao, Shaoxiong Wang, Xiongpeng Zhu
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
Background PDZ And LIM domain protein 1 (PDLIM1), a protein-coding gene, has been widely reported to exhibit differential expression patterns across various human cancers, including hematological malignancies. This study aimed to investigate PDLIM1 e
Externí odkaz:
https://doaj.org/article/9bd3520b9dcc4a0a9160955955fe4a30