Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Jinyang Gu"'
Autor:
Qichang Zheng, Tianhao Zou, Weimin Wang, Chen Zhang, Shaobo Hu, Xiang Cheng, Ran Liu, Guoliang Wang, Ping Sun, Xing Zhou, Bing Yang, Jianjun Xu, Yang Gao, Jinyang Gu
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Targeted delivery of glutamine metabolism inhibitors holds promise for cholangiocarcinoma therapy, yet effective delivery vehicles remain a challenge. This study reports the development of a biomimetic nanosystem, termed R‐CM@MSN@BC, integ
Externí odkaz:
https://doaj.org/article/6ae3304a7ae84e138e451605658e31b1
Autor:
Zhenzhong Deng, Yongkun Ji, Bing Han, Zhongming Tan, Yuqi Ren, Jinghan Gao, Nan Chen, Cong Ma, Yichi Zhang, Yunhai Yao, Hong Lu, Heqing Huang, Midie Xu, Lei Chen, Leizhen Zheng, Jianchun Gu, Deyi Xiong, Jianxin Zhao, Jinyang Gu, Zutao Chen, Ke Wang
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-23 (2023)
Abstract Background Early detection of hepatocellular carcinoma (HCC) is important in order to improve patient prognosis and survival rate. Methylation sequencing combined with neural networks to identify cell-free DNA (cfDNA) carrying aberrant methy
Externí odkaz:
https://doaj.org/article/37886a3f76464cfaa58cdc334466fdfa
Autor:
Xiaoqiang Li, Xiong Zhang, Junjie Zhang, Jinyang Gu, Shibiao Zhang, Guangyang Li, Jingai Shao, Yong He, Haiping Yang, Shihong Zhang, Hanping Chen
Publikováno v:
Carbon Capture Science & Technology, Vol 9, Iss , Pp 100146- (2023)
Machine learning provides new insights for designing MOFs with high CO2 adsorption capacity and understanding the CO2 adsorption mechanism. In this work, 348 data points from published reports were collected and four tree-based models were designed t
Externí odkaz:
https://doaj.org/article/28d4221e124a4d15989996b0cf9e9010
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Hepatocyte apoptosis plays an essential role in the progression of nonalcoholic steatohepatitis (NASH). However, the molecular mechanisms underlying hepatocyte apoptosis remain unclear. Here, we identify UDP-glucose 6-dehydrogenase (UGDH) as
Externí odkaz:
https://doaj.org/article/82c7fb2e83e7455d8e70dbc12828b84b
Autor:
Lingjie Yan, Tao Zhang, Kai Wang, Zezhao Chen, Yuanxin Yang, Bing Shan, Qi Sun, Mengmeng Zhang, Yichi Zhang, Yedan Zhong, Nan Liu, Jinyang Gu, Daichao Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The receptor-interacting protein (RIPK1) promotes cell death and contributes to nonalcoholic steatohepatitis pathogenesis. Here the authors report that a SUMO-specific protease, SENP1, deSUMOylates RIPK1 and inhibits cell death in a mouse model of no
Externí odkaz:
https://doaj.org/article/8a650a956901429b89dabaa947cacf14
Autor:
Yi Fu, Xindong Wei, Qiuqin Han, Jiamei Le, Yujie Ma, Xinjie Lin, Yuhui Xu, Ning Liu, Xuan Wang, Xiaoni Kong, Jinyang Gu, Ying Tong, Hailong Wu
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-18 (2021)
Abstract Background Early recurrence is the major cause of poor prognosis in hepatocellular carcinoma (HCC). Long non-coding RNAs (lncRNAs) are deeply involved in HCC prognosis. In this study, we aimed to establish a prognostic lncRNA signature for H
Externí odkaz:
https://doaj.org/article/c4961be88f4b4ac293edaf291f465930
Autor:
Ruitian Gao, Shuai Zhao, Kedeerya Aishanjiang, Hao Cai, Ting Wei, Yichi Zhang, Zhikun Liu, Jie Zhou, Bing Han, Jian Wang, Han Ding, Yingbin Liu, Xiao Xu, Zhangsheng Yu, Jinyang Gu
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-7 (2021)
Abstract Background Liver cancer remains the leading cause of cancer death globally, and the treatment strategies are distinct for each type of malignant hepatic tumors. However, the differential diagnosis before surgery is challenging and subjective
Externí odkaz:
https://doaj.org/article/df89ff64a65149f094eb41641bd92ac6
Autor:
Chunmei Yang, Hui Yuan, Jinyang Gu, Dengfei Xu, Mingwei Wang, Jie Qiao, Xi Yang, Jian Zhang, Ming Yao, Jianren Gu, Hong Tu, Yu Gan
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract The development of resistance to anticancer drugs is believed to cause chemotherapy failure in pancreatic cancer (PC). The efflux of anticancer drugs mediated by ATP-binding cassette (ABC) transporters is a widely accepted mechanism for chem
Externí odkaz:
https://doaj.org/article/cfec0cf095fb470a9e78555917810f4b
Autor:
Min Xu, Hualian Hang, Miao Huang, Jichang Li, Dongwei Xu, Junzhe Jiao, Fang Wang, Hailong Wu, Xuehua Sun, Jinyang Gu, Xiaoni Kong, Yueqiu Gao
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 567-584 (2021)
Background & Aims: DJ-1 is universally expressed in various tissues and organs and is involved in the physiological processes in various liver diseases. However, the role of DJ-1 in liver ischemia-reperfusion (I/R) injury is largely unknown. Methods:
Externí odkaz:
https://doaj.org/article/8fbaf959dcda432daf6ad86db891d678
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Ischemia-reperfusion injury can be divided into two phases, including insufficient supply of oxygen and nutrients in the first stage and then organ injury caused by immune inflammation after blood flow recovery. Hepatic ischemia-reperfusion is an imp
Externí odkaz:
https://doaj.org/article/85560b0207b34c36b27995096110bbaa