Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Jinxue Ruan"'
Autor:
Kaiyi Zhang, Ning Xie, Huaqiong Ye, Jiakun Miao, Boce Xia, Yu Yang, Huanqi Peng, Shuang Xu, Tianwen Wu, Cong Tao, Jinxue Ruan, Yanfang Wang, Shulin Yang
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108590- (2024)
Summary: Skeletal muscle is a highly plastic organ that adapts to different metabolic states or functional demands. This study explored the impact of permanent glucose restriction (GR) on skeletal muscle composition and metabolism. Using Glut4m mice
Externí odkaz:
https://doaj.org/article/41701b2e26f24b90b443040f37adc36b
Autor:
Youcai Xiong, Xiaoning Xi, Yue Xiang, Sheng Li, Hailong Liu, Yinyu Su, Ruigao He, Chong Xiong, Bingrong Xu, Xinyi Wang, Liangliang Fu, Changzhi Zhao, Xiaosong Han, Xinyun Li, Shengsong Xie, Jinxue Ruan
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13331 (2023)
The Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes viral encephalitis in humans, pigs and other mammals across Asia and the Western Pacific. Genetic screening tools such as CRISPR screening, DNA sequencing and RNA interf
Externí odkaz:
https://doaj.org/article/5178bc3bd5c74e368826121428ccf2d2
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/960771c71e2f4c02a474ebe49520eafa
Autor:
Jinfu Zhang, Siyi Hu, Changzhi Zhao, Yuan Zhou, Lu Zhang, Hailong Liu, Peng Zhou, Sheng Li, Liangliang Fu, Zhuqing Zheng, Yue Xiang, Xuewen Xu, Jinxue Ruan, Xinyun Li, Lvhui Sun, Gang Cao, Shuhong Zhao, Xu Wang, Shengsong Xie
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 446 (2023)
In the original publication [...]
Externí odkaz:
https://doaj.org/article/a019abc0b2314b3e82dce9742924c1ae
Autor:
Linyuan Ma, Jinxue Ruan, Jun Song, Luan Wen, Dongshan Yang, Jiangyang Zhao, Xiaofeng Xia, Y. Eugene Chen, Jifeng Zhang, Jie Xu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Cas9 fused to DNA damage repair proteins can improve rates of gene knock-in but the chimeric protein is often large. Here the authors fuse Cas9 to a minimal Brex27 motif from BRCA2 consisting of thirty-six amino acids to enhance the efficacy and safe
Externí odkaz:
https://doaj.org/article/58d62b4781c84e8aa9e7b4d0d8b4512d
Autor:
Xiaosong Han, Yang Gao, Guanglei Li, Youcai Xiong, Changzhi Zhao, Jinxue Ruan, Yunlong Ma, Xinyun Li, Changchun Li, Shuhong Zhao, Shengsong Xie
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-6 (2020)
Abstract Colostrum quality is a vital factor in mortality and growth performance for piglets. Lactoferrin is an immuno-active milk protein that contributes to the formation of a protective layer above intestinal mucosa, possesses the antibacterial an
Externí odkaz:
https://doaj.org/article/7fb1b5ff1fe4481096f1d49b5ec88077
Autor:
Changzhi Zhao, Hailong Liu, Tianhe Xiao, Zichang Wang, Xiongwei Nie, Xinyun Li, Ping Qian, Liuxing Qin, Xiaosong Han, Jinfu Zhang, Jinxue Ruan, Mengjin Zhu, Yi-Liang Miao, Bo Zuo, Kui Yang, Shengsong Xie, Shuhong Zhao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Here the authors report the construction of a genome-scale porcine CRISPR/Cas9 library, called PigGeCKO, for screening and analyses of host resistance genes and factors associated with Japanese encephalitis virus replication.
Externí odkaz:
https://doaj.org/article/c8d5432caf5247bdb69440141b17ee99
Autor:
Kemao Xiu, Laura Saunders, Luan Wen, Jinxue Ruan, Ruonan Dong, Jun Song, Dongshan Yang, Jifeng Zhang, Jie Xu, Y. Eugene Chen, Peter X. Ma
Publikováno v:
Cells, Vol 12, Iss 1, p 156 (2022)
Gene editing nucleases such as CRISPR/Cas9 have enabled efficient and precise gene editing in vitro and hold promise of eventually achieving in vivo gene editing based therapy. However, a major challenge for their use is the lack of a safe and effect
Externí odkaz:
https://doaj.org/article/93602edda32c46029d7ed99e5661f88a
Autor:
Jinfu Zhang, Siyi Hu, Changzhi Zhao, Yuan Zhou, Lu Zhang, Hailong Liu, Peng Zhou, Sheng Li, Liangliang Fu, Zhuqing Zheng, Yue Xiang, Xuewen Xu, Jinxue Ruan, Xinyun Li, Lvhui Sun, Gang Cao, Shuhong Zhao, Xu Wang, Shengsong Xie
Publikováno v:
Antioxidants, Vol 11, Iss 9, p 1787 (2022)
Aflatoxin B1 (AFB1) is amongst the mycotoxins commonly affecting human and animal health, raising global food safety and control concerns. The mechanisms underlying AFB1 toxicity are poorly understood. Moreover, antidotes against AFB1 are lacking. Ge
Externí odkaz:
https://doaj.org/article/fbe1ebe0d5844450ae2c09e72da25a26
Autor:
Kaiyi Zhang, Cong Tao, Jianping Xu, Jinxue Ruan, Jihan Xia, Wenjuan Zhu, Leilei Xin, Huaqiong Ye, Ning Xie, Boce Xia, Chenxiao Li, Tianwen Wu, Yanfang Wang, Martine Schroyen, Xinhua Xiao, Jiangao Fan, Shulin Yang
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Anti-inflammatory therapies have the potential to become an effective treatment for obesity-related diseases. However, the huge gap of immune system between human and rodent leads to limitations of drug discovery. This work aims at constructing a tra
Externí odkaz:
https://doaj.org/article/6c2250577b6a41038a1846f1c1e28547