Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jinxiong Wei"'
Publikováno v:
PLoS Pathogens, Vol 11, Iss 9, p e1005099 (2015)
p53 tumor suppressor has been identified as a protein interacting with the large T antigen produced by simian vacuolating virus 40 (SV40). Subsequent research on p53 inhibition by SV40 and other tumor viruses has not only helped to gain a better unde
Externí odkaz:
https://doaj.org/article/1a6a71f61f99485e8aa6e5f0d93fc838
Autor:
Elena Zaika, Vikas Bhardwaj, Jinxiong Wei, Mary Kay Washington, Rhonda Souza, Wael El-Rifai, Alexander Zaika
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64306 (2013)
Gastroesophageal reflux disease (GERD) is the main etiological factor behind the recent rapid increase in the incidence of esophageal adenocarcinoma. During reflux, esophageal cells are exposed to bile at low pH resulting in cellular damage and infla
Externí odkaz:
https://doaj.org/article/97b60187fa50485ba3a431869ae105ec
Publikováno v:
Journal of Nucleic Acids, Vol 2012 (2012)
TP53, TP63, and TP73 genes comprise the p53 family. Each gene produces protein isoforms through multiple mechanisms including extensive alternative mRNA splicing. Accumulating evidence shows that these isoforms play a critical role in the regulation
Externí odkaz:
https://doaj.org/article/62c92e091d334af7ad11208366b8123e
Autor:
Jinxiong Wei, Alexander Zaika, Andela Horvat, Richard M. Peek, Wael El-Rifai, Jennifer M. Noto, Barbara G. Schneider, Manikandan Palrasu, Elena Zaika, Balamurugan Ramatchandirin
Publikováno v:
Oncogene
Infection with Helicobacter pylori is one of the strongest risk factors for development of gastric cancer. Although these bacteria infect approximately half of the world's population, only a small fraction of infected individuals develops gastric mal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a068df72961b532e643d058019e3107
https://www.bib.irb.hr/970651
https://www.bib.irb.hr/970651
Autor:
Jinxiong Wei, Alexander Zaika, Richard M. Peek, Claudia D. Andl, Vikas Bhardwaj, Wael El-Rifai, Jennifer M. Noto
Publikováno v:
Oncotarget
H. pylori infection is the strongest known risk factor for gastric cancer. Inhibition of host tumor suppressor mechanisms by the bacteria underlies the development of this disease. Among the tumor suppressors affected by H. pylori are p53 and E-cadhe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ac29669896042ab5ccb99caf7a9738
https://doi.org/10.18632/oncotarget.2828
https://doi.org/10.18632/oncotarget.2828
Autor:
Dengping Yin, Alexander Zaika, Ute M. Moll, Claudia D. Andl, Jinxiong Wei, Wael El-Rifai, Elena Zaika
Publikováno v:
The FASEB Journal. 25:4406-4414
Although the p53 tumor suppressor is relatively well characterized, much less is known about the functions of other members of the p53 family, p73 and p63. Here, we present evidence that in specific pathological conditions caused by exposure of norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ba46ea1c7e400cb042cc7122fd8385c
https://doi.org/10.1096/fj.11-192815
https://doi.org/10.1096/fj.11-192815
Autor:
Jinxiong Wei, Alexander Zaika, Heidi Chen, Seung-Mo Hong, Anna E. Vilgelm, Mary Kay Washington, Wail El-Rifai
Publikováno v:
Oncogene. 29:5861-5868
p73 is a member of the p53 protein family. Although the tumor suppressor function of p53 is clearly defined, the role of p73 in tumorigenesis is still a matter of debate. A complex pattern of expression of p73 isoforms makes it difficult to unambiguo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ee19ec8012fb9edd0dd6c21faef00b
https://doi.org/10.1038/onc.2010.319
https://doi.org/10.1038/onc.2010.319
Autor:
Mary Kay Washington, Maria Blanca Piazuelo, Jinxiong Wei, Alexander Zaika, Pelayo Correa, Daniel O'Brien, Wael El-Rifai, Richard M. Peek, Anna E. Vilgelm
Publikováno v:
Gastroenterology. 134:1412-1423
Background & Aims: Although the p53 tumor suppressor has been extensively studied, many critical questions remain unanswered about the biological functions of p53 homologs, p73 and p63. Accumulating evidence suggests that both p73 and p63 play import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e41d5bce62c8b0085bf8e183149e482
https://doi.org/10.1053/j.gastro.2008.01.072
https://doi.org/10.1053/j.gastro.2008.01.072
Autor:
Vladimir S. Prassolov, Alexander Zaika, Jinxiong Wei, Anna E. Vilgelm, Wael El-Rifai, Mary Kay Washington, Maria Blanca Piazuelo
Publikováno v:
Oncogene. 27:2170-2176
The p73 protein is a transcription factor and member of the p53 protein family that expresses as a complex variety of isoforms. DeltaNp73alpha is an N-terminally truncated isoform of p73. We found that DeltaNp73 protein is upregulated in human gastri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fc3e58ab1ab258c8f30914607b7dd7
https://doi.org/10.1038/sj.onc.1210862
https://doi.org/10.1038/sj.onc.1210862
Autor:
Pelayo Correa, Alexander Zaika, Elena Zaika, Jinxiong Wei, Barbara G. Schneider, Richard M. Peek, Wael El-Rifai, Maria Blanca Piazuelo, Jennifer M. Noto, Judith Romero-Gallo
Publikováno v:
Gut. 64(7)
Objective Infection with Helicobacter pylori is the strongest known risk factor for adenocarcinoma of the stomach. Tumorigenic transformation of gastric epithelium induced by H. pylori is a highly complex process driven by an active interplay between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ed74041f675ec04be8e153b0468cf7
https://pubmed.ncbi.nlm.nih.gov/25080447
https://pubmed.ncbi.nlm.nih.gov/25080447