Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jinxiao Yang"'
Publikováno v:
Sensors, Vol 24, Iss 15, p 4823 (2024)
This study proposes a dual-functional terahertz device based on the Dirac semimetal, serving as both a sensing element and a band-pass filter. The device’s operating mode can switch between these two functions by utilizing the phase transition prop
Externí odkaz:
https://doaj.org/article/1ec78637b8714c1da83cf0787dd1027d
Autor:
Feipeng Wang, Chengwei Zhang, Wen Xu, Shuang Yuan, Jinling Song, Lu Li, Jiuran Zhao, Jinxiao Yang
Publikováno v:
Crop Journal, Vol 8, Iss 3, Pp 408-417 (2020)
The clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein (Cas) system has been widely used for genome editing. In this system, the cytosine base editor (CBE) and adenine base editor (ABE) allow generating pre
Externí odkaz:
https://doaj.org/article/1b39cdf081be4a269029b743eb2232fe
Publikováno v:
Crop Journal, Vol 8, Iss 3, Pp 418-423 (2020)
Base editing, as an expanded clustered regularly interspaced short palindromic repeats (CRISPR)-Cas genome editing strategy, permits precise and irreversible nucleotide conversion. SaKKH, an efficient variant of a Cas9 ortholog from Staphylococcus au
Externí odkaz:
https://doaj.org/article/68f4ffec3ab44645a673cc5c14a0ad8f
Publikováno v:
International Journal of Endocrinology, Vol 2022 (2022)
Background. Hormone status strongly affects women’s health and quality of life. To date, studies investigating the association between total testosterone (T) level and bone mineral density (BMD) in women are limited and have yielded contradictory c
Externí odkaz:
https://doaj.org/article/0a7ffef5446642488f2f2a50863e3fa3
Publikováno v:
BMC Plant Biology, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Application of the CRISPR/Cas9 system or its derived base editors enables targeted genome modification, thereby providing a programmable tool to exploit gene functions and to improve crop traits. Results We report that PmCDA1 is m
Externí odkaz:
https://doaj.org/article/eeaa5c7a69904823998c4a1b4e6c1211
Autor:
Jiaxin Fan, Yanru Fan, Xiao Wang, Lingfang Niu, Limei Duan, Jinxiao Yang, Luo Li, Yingying Gao, Xiaohou Wu, Chunli Luo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Metabolic rewiring is a common feature of many cancer types, including prostate cancer (PCa). Alterations in master genes lead to mitochondrial metabolic rewiring and provide an appealing target to inhibit cancer progression and i
Externí odkaz:
https://doaj.org/article/3d71d4b13855430dac2408a474b96dd5
Publikováno v:
International Journal of Endocrinology, Vol 2021 (2021)
Introduction. Sex hormones play an important role in the development and maintenance of bone and muscle mass. However, studies regarding serum testosterone levels, osteoporosis, and sarcopenia in men are relatively sparse and have led to contradictor
Externí odkaz:
https://doaj.org/article/483d6539aea443d4ba2cef3118cdcfe4
Autor:
Chengwei Zhang, Guiting Kang, Xinxiang Liu, Si Zhao, Shuang Yuan, Lu Li, Yongxing Yang, Feipeng Wang, Xiang Zhang, Jinxiao Yang
Publikováno v:
Frontiers in Genome Editing, Vol 2 (2020)
The CRISPR-Cas9 system enables simple, rapid, and effective genome editing in many species. Nevertheless, the requirement of an NGG protospacer adjacent motif (PAM) for the widely used canonical Streptococcus pyogenes Cas9 (SpCas9) limits the potenti
Externí odkaz:
https://doaj.org/article/6a035509dce5414a857ad7568d1df735
Autor:
Jiayu Liu, Yongbo Zheng, Yingying Gao, Zhen Quan, Bo Qiao, Luo Li, Ting Li, Limei Duan, Jinxiao Yang, Chunli Luo, Xiaohou Wu
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Castration-resistant prostate cancer (CRPC) is a progressed stage of prostate cancer, which requires better understanding of the mechanisms and remains an unmet clinical need. As a common oncogene, K-Ras is associated with malignant behavior in diffe
Externí odkaz:
https://doaj.org/article/313f7147e29c42a2bea8decd07d9c3c0
Autor:
Ying Wu, Wen Xu, Feipeng Wang, Si Zhao, Feng Feng, Jinling Song, Chengwei Zhang, Jinxiao Yang
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Base editors that do not require double-stranded DNA cleavage or homology-directed repair enable higher efficiency and cleaner substitution of targeted single nucleotides in genomic DNA than conventional approaches. However, their broad applications
Externí odkaz:
https://doaj.org/article/eb251d0545234bc0a1d3e08cafe48047