Zobrazeno 1 - 10
of 297
pro vyhledávání: '"Jinxia Li"'
Autor:
Qianwei Zhao, Mengdan Yu, Jinxia Li, Yaoyu Guo, Zexuan Wang, Kefei Hu, Fang Xu, Yixian Liu, Lili Li, Didi Wan, Ying Zhao, Jian Shang, Jintao Zhang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Glutamate dehydrogenase 1 (GLUD1) is an important enzyme in glutamine metabolism. Previously, we found GLUD1 was down-regulated in tumor tissues of hepatocellular carcinoma (HCC) patients by proteomics study. To explore its role in the progr
Externí odkaz:
https://doaj.org/article/946d33c145f54dd48822c8ebd36883d1
Autor:
Chenchen Zhao, Jinxia Li, Menglin Liu, Linfang Chen, Yiwei Zhu, Wenwen Gao, Xiliang Du, Yuxiang Song, Guowen Liu, Lin Lei, Xinwei Li
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 12, Pp 9186-9199 (2023)
ABSTRACT: When ketosis occurs, supraphysiological concentrations of nonesterified fatty acids (NEFA) display lipotoxicity and are closely related to the occurrence of hepatic lipid accumulation, oxidative stress, and inflammation, resulting in hepati
Externí odkaz:
https://doaj.org/article/cdf4a48c71664b939110998cc65b85cf
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background Investigate the AMPK (protein kinase AMP-activated catalytic subunit alpha 1)/YAP (Yes1 associated transcriptional regulator)/NLRP3 (NLR family pyrin domain containing 3) signaling pathway's role in ankylosing spondylitis (AS) dev
Externí odkaz:
https://doaj.org/article/091aabfbfd2f4297a9fe34dcc9591887
Autor:
Chenchen Zhao, Bing Wu, Jinxia Li, Qianming Jiang, Juan J. Loor, Menglin Liu, Linfang Chen, Yiwei Zhu, Wenwen Gao, Xiliang Du, Yuxiang Song, Guowen Liu, Lin Lei, Xinwei Li
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 8, Pp 5763-5774 (2023)
ABSTRACT: During the transition period in dairy cows, high circulating concentrations of nonesterified fatty acids (NEFA) increase hepatic lipid deposits and are considered a major pathological factor for liver damage. We investigated whether AdipoRo
Externí odkaz:
https://doaj.org/article/d02638baef5c48f9b6116d2214875ffc
Autor:
Yiwei Zhu, Lin Lei, Xinghui Wang, Qianming Jiang, Juan J. Loor, Fanrong Kong, Linfang Chen, Jinxia Li, Chenchen Zhao, Menglin Liu, Guowen Liu, Xinwei Li
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 8, Pp 5626-5635 (2023)
ABSTRACT: Fatty liver is a major metabolic disorder of high-producing dairy cows during the transition period. In nonruminants, it is well established that insulin-induced gene 1 (INSIG1) plays a crucial role in regulating hepatic lipogenesis by cont
Externí odkaz:
https://doaj.org/article/577685ab455f4c3b9781774d206f3236
Autor:
Hao Peng, Yuyu Yan, Min He, Jinxia Li, Lianghai Wang, Wei Jia, Lan Yang, Jinfang Jiang, Yunzhao Chen, Feng Li, Xianglin Yuan, Lijuan Pang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 6, Pp 1-16 (2023)
Abstract Studies have indicated dietary restriction of methionine/cystine provided a therapeutic benefit in diseases such as cancer. However, the molecular and cellular mechanisms that underlie the interaction between methionine/cystine restriction (
Externí odkaz:
https://doaj.org/article/0d3c9008ca39402799283594a81c7d91
Publikováno v:
Gastroenterology Research and Practice, Vol 2024 (2024)
Objective. This study is aimed at investigating the expression of Met and YAP in gastric cancer and their impact on clinical prognosis. Methods. Tissue samples and clinical data were collected from 89 patients with gastric cancer. Immunohistochemistr
Externí odkaz:
https://doaj.org/article/ee17cd1150e94aa69958ca5af5f26e5e
Autor:
Yiwei Zhu, Lin Lei, Xinghui Wang, Linfang Chen, Wei Li, Jinxia Li, Chenchen Zhao, Xiliang Du, Yuxiang Song, Wenwen Gao, Guowen Liu, Xinwei Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1616-1630 (2023)
Acetaminophen (APAP) overdose is a major cause of liver injury. Neural precursor cell expressed developmentally downregulated 4–1 (NEDD4-1) is an E3 ubiquitin ligase that has been implicated in the pathogenesis of numerous liver diseases; however,
Externí odkaz:
https://doaj.org/article/2f751177a198487ba16915dde2a60c77
Autor:
Shengnan Jin, Jinxia Li, Kang Liu, Wei-Yi Ding, Shuai Wang, Xiujuan Huang, Xue Li, Peiyuan Yu, Qiuling Song
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Optically enriched 1,1-diboron compounds are significantly underdeveloped because of the paucity of the straightforward synthetic protocols. Herein, the authors report an enantioselective copper-catalyzed cascade double hydroboration of terminal alky
Externí odkaz:
https://doaj.org/article/535b68af3982405cae8c6c790b75f361
Autor:
Shengnan Jin, Jinxia Li, Kang Liu, Wei-Yi Ding, Shuai Wang, Xiujuan Huang, Xue Li, Peiyuan Yu, Qiuling Song
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/78835c1b20e144098ba677d34748cf7f