Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jinxi Liao"'
Autor:
Xiaopei Wu, Jinsheng Lai, Kexin Yang, Yunxia Xue, Jinxi Liao, Liming Wang, Jian‐song Sun, Jing Hu, Jian Yin, Qingju Zhang
Publikováno v:
Chinese Journal of Chemistry. 41:535-543
Autor:
Ke Xiao, Yongxin Hu, Yongyong Wan, XinXin Li, Qin Nie, Hao Yan, Liming Wang, Jinxi Liao, Deyong Liu, Yuanhong Tu, Jiansong Sun, Jeroen D. C. Codée, Qingju Zhang
Publikováno v:
Chemical Science, 13(6), 1600-1607. ROYAL SOC CHEMISTRY
Herein, we report a new glycosylation system for the highly efficient and stereoselective formation of glycosidic bonds using glycosyl N-phenyl trifluoroacetimidate (PTFAI) donors and a charged thiourea hydrogen-bond-donor catalyst. The glycosylation
Autor:
Yanmei Zhang, Zhengchao Tu, Jufang He, Micky D. Tortorella, Ke Ding, Yiping Guo, Wang Yican, Yongzhi Lu, Jinxi Liao
Publikováno v:
Medicinal Chemistry Research. 28:387-393
Recently, He et al. reported that CCKB receptors located in the neocortex of the brain when bound to their bound natural ligand, CCK peptides, enhance memory, bringing up the possibility that agonists targeting the CCKB receptor may act as therapeuti
Autor:
Huimin Cheng, Yingjun Li, Zhengchao Tu, Yanmei Zhang, Ke Ding, Micky D. Tortorella, Jinxi Liao, Panyu Chen, Junting Wan
Publikováno v:
Open Journal of Medicinal Chemistry. :43-50
Virus nucleoprotein (NP) is an emerging target for drug development for Influenza. We designed benzamide derivatives as new inhibitors of NP that demonstrate good potency in blocking influenza A. Screening revealed that compound 39 was the most poten
Synthesis and Evaluation of Novel Erlotinib–NSAID Conjugates as More Comprehensive Anticancer Agents
Autor:
Micky D. Tortorella, Guan Jiantong, Jinfeng Luo, Yanmei Zhang, Jinxi Liao, Xiao-Chu Qin, Tingting Chen, Zhengchao Tu, John J. Talley
Publikováno v:
ACS Medicinal Chemistry Letters. 6:1086-1090
A series of novel anticancer agents were designed and synthesized based on coupling of different nonsteroidal anti-inflammatory drugs (NSAIDs) with the epidermal growth-factor receptor (EGFR) tyrosine kinase inhibitor, erlotinib. Both the antiprolife
Publikováno v:
Organic Letters. 15:2478-2481
A novel and efficient Pd-catalyzed one-pot reaction of ethyl diazoacetate, isocyanides, and imines for the synthesis of acrylamidines was developed. The multicomponent reaction may have occurred through an unpredicted ring-opening process of the kete
Publikováno v:
Tetrahedron Letters. 52:3075-3078
Glycosylation of the acid labile protopanaxadiol derivatives was succeeded with a glycosyl ortho -hexynylbenzoate as donor under the catalysis of PPh 3 AuNTf 2 , leading to the subsequent elaboration of ginsenoside Rh2 and chikusetsusaponin-LT8 in a
Publikováno v:
Tetrahedron Letters. 49:5036-5038
Glycosyl trifluoroacetimidates have been disclosed to be effective glycosyl donors for the synthesis of nucleosides; the present N-glycosylation protocol requires only a catalytic amount of TMSOTf as promoter and proceeds smoothly at room temperature
Publikováno v:
ChemInform. 44
The title multicomponent reaction proceeds through an unpredicted ring-opening process of the ketenimine-imine [2 + 2] intermediate.
Publikováno v:
Carbohydrate research. 344(8)
Using glycosyl trifluoroacetimidates as donors and nitromethane (or acetonitrile) as solvent, silylation and subsequent glycosylation were realized in a 'one-pot' procedure to provide the corresponding nucleosides derivatives in high yields. [structu