Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jinwen Shan"'
Autor:
Feng Zhou, Guimei Yang, Liting Xue, Yajing Liu, Yao Guo, Ji Zhu, Linlin Yuan, Peng Gu, Feng Tang, Jinwen Shan, Renhong Tang
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Background Targeted estrogen receptor degradation has been approved to effectively treat ER + breast cancers. Due to the poor bioavailability of fulvestrant, the first generation of SERD, many efforts were made to develop oral SERDs. With th
Externí odkaz:
https://doaj.org/article/c46650e722a24e6cba59976a6289940d
Autor:
Feng Zhou, Guimei Yang, Liting Xue, Yajing Liu, Yao Guo, Ji Zhu, Linlin Yuan, Peng Gu, Feng Tang, Jinwen Shan, Renhong Tang
Background: Targeted estrogen receptor degradation has been approved to effectively treat ER + breast cancers. Due to the poor bioavailability of fulvestrant, the first generation of SERD, many efforts were made to develop oral SERDs. With the approv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3daa66ee93e79f2c365620ce095ab692
https://doi.org/10.21203/rs.3.rs-2863986/v1
https://doi.org/10.21203/rs.3.rs-2863986/v1
Publikováno v:
Journal of Chemical Information and Modeling. 60:5900-5906
The design of efficient computational tools for structure-guided ligand design is essential for the drug discovery process. We hereby present FragRep, a new web server for structure-based ligand design by fragment replacement. The input is a protein
Autor:
Changge Ji, Jinwen Shan
Publikováno v:
Current Computer-Aided Drug Design. 16:460-466
Background: Bioisosteric replacement is widely used in drug design for lead optimization. However, the identification of a suitable bioisosteric group is not an easy task. Methods: In this work, we present MolOpt, a web server for in silico drug desi
Autor:
Chengjuan Zhang, Junxia Zhang, Qiong Wu, Benling Xu, Guoguo Jin, Yan Qiao, Simin Zhao, Yang Yang, Jinwen Shang, Xiaofang Li, Kangdong Liu
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background As a novel type of isothiocyanate derived from radish seeds from cruciferous vegetables, sulforaphene (SFE, 4-methylsufinyl-3-butenyl isothiocyanate) has various important biological effects, such as anti-oxidative and anti-bacter
Externí odkaz:
https://doaj.org/article/aa406029d205433bbe0d6dfe9925efd9