Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jinwei, Chai"'
Autor:
Huimei Wu, Mohamed Amine Jmel, Jinwei Chai, Maolin Tian, Xueqing Xu, Yuan Hui, Kutty Selva Nandakumar, Michail Kotsyfakis
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Protease inhibitors regulate various biological processes and prevent host tissue/organ damage. Specific inhibition/regulation of proteases is clinically valuable for treating several diseases. Psoriasis affects the skin in the limbs and scalp of the
Externí odkaz:
https://doaj.org/article/6df55cf4aa314dbcbcdc32af46c3d186
Autor:
Weichen Xiong, Jinwei Chai, Jiena Wu, Jiali Li, Wancheng Lu, Maolin Tian, Mohamed Amine Jmel, Johannes H. Ippel, Michail Kotsyfakis, Ingrid Dijkgraaf, Shuwen Liu, Xueqing Xu
Publikováno v:
Research, Vol 7 (2024)
Platelet activation contributes to sepsis development, leading to microthrombosis and increased inflammation, which results in disseminated intravascular coagulation and multiple organ dysfunction. Although Cathelicidin can alleviate sepsis, its role
Externí odkaz:
https://doaj.org/article/2b78b0646b8343c88ecc86240cd764e2
Autor:
Maolin Tian, Kai Wang, Yan Liang, Jinwei Chai, Jiena Wu, Haiyun Zhang, Xiaowen Huang, Xin Chen, Xueqing Xu
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Antimicrobial peptide is one important component of the first protective barrier of organisms. They not only have potent antimicrobial activity which can protect the body from the invading pathogens, but also participate in the immune regulation of t
Externí odkaz:
https://doaj.org/article/a6d0459f5dae42109d8d6243960f86b4
Autor:
Ze Deng, Yahua Gao, Tienthanh Nguyen, Jinwei Chai, Jiena Wu, Jiali Li, Mohamed A. Abdel-Rahman, Xueqing Xu, Xin Chen
Publikováno v:
Toxins, Vol 15, Iss 5, p 347 (2023)
Research has been conducted to investigate the potential application of scorpion venom-derived peptides in cancer therapy. Smp43, a cationic antimicrobial peptide from Scorpio maurus palmatus venom, has been found to exhibit suppressive activity agai
Externí odkaz:
https://doaj.org/article/3697dd1d1043442fa6aadbb45244918e
Autor:
Weichen Xiong, Chenliang Zhou, Shuwen Yin, Jinwei Chai, Baishuang Zeng, Jiena Wu, Yibin Li, Lin Li, Xueqing Xu
Publikováno v:
ACS Omega, Vol 6, Iss 9, Pp 6414-6423 (2021)
Externí odkaz:
https://doaj.org/article/4fa50aba738443888ac856e9a7af1e52
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Acne vulgaris is a common adolescent skin condition which is mainly caused by Propionibacterium acnes overcolonization and subsequent inflammation. Our previous studies have demonstrated that Cath-MH, an antimicrobial peptide from the skin of the fro
Externí odkaz:
https://doaj.org/article/0fdc4ccad62c4629b392d6fc4e492c62
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Brevinins are an important antimicrobial peptide (AMP) family identified in the skin of Ranidae frogs and generally contain a characteristic ranabox structure at their C-terminal sequence. Herein a novel AMP named brevinin-2MP has been identified fro
Externí odkaz:
https://doaj.org/article/2999d2ce3b17414e8a0c4fb14d534575
Autor:
Tienthanh Nguyen, Ruiyin Guo, Jinwei Chai, Jiena Wu, Junfang Liu, Xin Chen, Mohamed A. Abdel-Rahman, Hu Xia, Xueqing Xu
Publikováno v:
Toxins, Vol 14, Iss 10, p 717 (2022)
Scorpion-venom-derived peptides have become a promising anticancer agent due to their cytotoxicity against tumor cells via multiple mechanisms. The suppressive effect of the cationic antimicrobial peptide Smp24, which is derived from the venom of Sco
Externí odkaz:
https://doaj.org/article/bbcdafa005a84d85bebed163c46cc174
Autor:
Jiena Wu, Haiyun Zhang, Xiaoxin Chen, Jinwei Chai, Yunrui Hu, Weichen Xiong, Wancheng Lu, Maolin Tian, Xin Chen, Xueqing Xu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Sepsis is an exacerbated inflammatory reaction induced by severe infection. As important defensive molecules in innate immunity, several AMPs are reported to prevent septic shock. In this study, we characterized a novel cathelicidin, FM-CATH, from th
Externí odkaz:
https://doaj.org/article/c4b5af2d90df4df6863722a4d0245478
Autor:
Ruiyin Guo, Xuewen Chen, Tienthanh Nguyen, Jinwei Chai, Yahua Gao, Jiena Wu, Jinqiao Li, Mohamed A. Abdel-Rahman, Xin Chen, Xueqing Xu
Publikováno v:
Toxins, Vol 14, Iss 9, p 590 (2022)
Non-small cell lung cancer (NSCLC) is the leading cause of death in lung cancer due to its aggressiveness and rapid migration. The potent antitumor effect of Smp24, an antimicrobial peptide derived from Egyptian scorpion Scorpio maurus palmatus via d
Externí odkaz:
https://doaj.org/article/736b129e81db45bfbb02f882c6f83c9c