Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Jinu Lee"'
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-15 (2024)
Abstract Skeletal muscle possesses remarkable regenerative capabilities, fully recovering within a month following severe acute damage. Central to this process are muscle satellite cells (MuSCs), a resident population of somatic stem cells capable of
Externí odkaz:
https://doaj.org/article/826872603eed406d8f8c292391cbd364
Autor:
Seol Hwa Seong, Ji Young Kim, Sung Hee Kim, Joohee Lee, Eun Jung Lee, Yu Jeong Bae, Sujin Park, Il Joo Kwon, Sei-Mee Yoon, Jinu Lee, Tae-Gyun Kim, Sang Ho Oh
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 282, Iss , Pp 116738- (2024)
Abstracts: Air pollution, a global health concern, has been associated with adverse effects on human health. In particular, particulate matter (PM), which is a major contributor to air pollution, impacts various organ systems including the skins. In
Externí odkaz:
https://doaj.org/article/37bd2142c03e468f86be65cdb4073c53
Autor:
Jung Hwa Seo, Jeong Hong Shin, Junwon Lee, Daesik Kim, Hye-Yeon Hwang, Bae-Geun Nam, Jinu Lee, Hyongbum Henry Kim, Sung-Rae Cho
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Huntington’s disease (HD) is caused by a CAG repeat expansion in the huntingtin (HTT) gene. CRISPR-Cas9 nuclease causes double-strand breaks (DSBs) in the targeted DNA that induces toxicity, whereas CRISPR interference (CRISPRi) using dead
Externí odkaz:
https://doaj.org/article/ec1c423e00d74e488b61cd13642bddcb
Autor:
Cho Eun Kang, Seungeun Lee, Taeyoung Ahn, Dong Hye Seo, Byoung Joon Ko, Minkyu Jung, Jinu Lee, Joo Young Kim, Woo Taek Kim
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Cancer therapy using immune checkpoint inhibitor antibodies has markedly shifted the paradigm of cancer treatment. However, methods completely eliminating the effector function of these signal-regulating antibodies is urgently required. The
Externí odkaz:
https://doaj.org/article/4cd3966e5f2a48ce9677078ff3077d7f
Autor:
Jones Gyamfi, Joo Hye Yeo, Doru Kwon, Byung Soh Min, Yoon Jin Cha, Ja Seung Koo, Joon Jeong, Jinu Lee, Junjeong Choi
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-18 (2021)
Abstract Adipocytes influence breast cancer behaviour via fatty acid release into the tumour microenvironment. Co-culturing human adipocytes and breast cancer cells increased CD36 expression, with fatty acid import into breast cancer cells. Genetic a
Externí odkaz:
https://doaj.org/article/a156fe2efe22458ca29d0ef7df1fc3eb
Autor:
Mi Kyung Lim, Soyeon Lee, Ju Yeon Kim, Jeongho Jeong, Eun Hye Han, Sang Ho Lee, Jong Hoon Ryu, Jinu Lee
Publikováno v:
Journal of Functional Foods, Vol 79, Iss , Pp 104400- (2021)
Aster glehni Fr. Schm. has been reported ameliorating effects on cognitive dysfunction. However, the molecular mechanisms underlying neurodegenerative diseases such as Alzheimer’s disease (AD) are poorly understood. Herein, we examined whether the
Externí odkaz:
https://doaj.org/article/248644c2ae0541c9acacaa9e4d5ce8af
Autor:
Sang-Nam Kim, Hyun-Jung Kwon, Seo-Woo Im, Yeon-Ho Son, Seun Akindehin, Young-Suk Jung, Se Jeong Lee, Im Joo Rhyu, Il Yong Kim, Je-Kyoung Seong, Jinu Lee, Hee-Chan Yoo, James G. Granneman, Yun-Hee Lee
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract We investigated the role of connexin 43 (Cx43) in maintaining the integrity of mitochondria in brown adipose tissue (BAT). The functional effects of Cx43 were evaluated using inducible, adipocyte-specific Cx43 knockout in mice (Gja1 adipoq K
Externí odkaz:
https://doaj.org/article/447d2147654f468aa1f2190154e48614
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222326 (2019)
Gap junctions (GJs), which consist of proteins called connexins, are intercellular channels that allow the passage of ions, second messengers, and small molecules. GJs and connexins are considered as emerging therapeutic targets for various diseases.
Externí odkaz:
https://doaj.org/article/162a23fcb69b4e8ab778e6feed31b930
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1389 (2020)
Gap junctions (GJs) are intercellular channels that connect adjacent cells electrically and metabolically. The iodide-yellow fluorescent protein (I-YFP) gap junctional intercellular communication (GJIC) assay is a recently developed method with high
Externí odkaz:
https://doaj.org/article/3464abe86b914a2daf121c31b30b184d
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Gap junctions (GJs) are intercellular channels composed of connexins. Cellular molecules smaller than 1 kDa can diffuse through GJs by a process termed gap junctional intercellular communication (GJIC), which plays essential roles in various patholog
Externí odkaz:
https://doaj.org/article/79b7226561c140c0bcfc2ab6d0efc502