Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jintang Du"'
Autor:
Yuhan Zhang, Feng Wang, Anzhi Yao, Xiaoxuan Lyu, Sean A. Reed, Xiaozhou Luo, Peng-Yu Yang, Chunhui Huang, Xueyong Zhu, Renhe Liu, Peter G. Schultz, Rongsheng E. Wang, Weimin Xuan, Ian A. Wilson, Mingchao Kang, Claudio Zambaldo, Tao Liu, Guangsen Fu, Hui Guo, Jintang Du
Publikováno v:
Nature chemical biology
Tyrosine phosphorylation is a common protein posttranslational modification, which plays a critical role in signal transduction and the regulation of many cellular processes. Using a pro-peptide strategy to increase cellular uptake of O-phosphotyrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94dc84c54ebf75d6a7e032304bb4e894
http://europepmc.org/articles/PMC5577365
http://europepmc.org/articles/PMC5577365
Autor:
Van Nguyen-Tran, Huafei Zou, Elizabeth Chao, Jose Gonzalez, Danling Wang, Weijun Shen, Yuhan Zhang, Peter G. Schultz, Peng-Yu Yang, Feng Wang, Ying Wang, Jintang Du, Lucy Lu, Yan Liu, Holly Parker
Publikováno v:
Angewandte Chemie. 128:12663-12666
Glucagon-like peptide-1 (GLP-1) receptor (GLP-1R), glucagon (GCG) receptor (GCGR), and glucose-dependent insulinotropic polypeptide (GIP, also known as gastric inhibitory polypeptide) receptor (GIPR), are three metabolically related peptide hormone r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d924f849ef9552ebde8c06a28da7b6c
https://doi.org/10.1002/ange.201606321
https://doi.org/10.1002/ange.201606321
Autor:
Xiaozhou Luo, Ying Wang, Travis S. Young, Yu Cao, V. Deshmukh, Feng Wang, Brian R. Lawson, Stephanie A. Kazane, Tao Liu, Chan Hyuk Kim, Matthew S. Tremblay, Rongsheng E. Wang, Jintang Du, Peter G. Schultz
Publikováno v:
Journal of the American Chemical Society. 137:3229-3232
We have developed a novel antibody drug-conjugate (ADC) which can selectively deliver the Lck inhibitor dasatinib to human T lymphocytes. This ADC is based on a humanized antibody which selectively binds with high affinity to CXCR4, an antigen that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1407232a49fc85a20b0f2fc4c832adbb
https://doi.org/10.1021/jacs.5b00620
https://doi.org/10.1021/jacs.5b00620
Autor:
Jeanne F. Loring, Wenyan Miao, Elisabetta Soragni, Myriam Rai, Pablo Penalver, Joseph C. Madara, David Jacoby, Joel M. Gottesfeld, Massimo Pandolfo, Stefania Federica De Mercanti, Jintang Du, Filomena Longo, James R. Rusche, Melinda O'Connor, Antonio Piga, Kristopher L. Nazor, Sherman Ku, Marco Iudicello, Anton Maximov, L. Durelli, Marinella Clerico, Erica Campau
Publikováno v:
Annals of Neurology. 76:489-508
Friedreich ataxia (FRDA; Online Mendelian Inheritance in Man database #229300) is an autosomal recessive inherited degenerative disorder affecting the nervous system and the heart, with a prevalence of approximately 2 to 3 in 100,000 in North America
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69ea804bced20fdf216b7ae81cdbe7c9
https://doi.org/10.1002/ana.24260
https://doi.org/10.1002/ana.24260
Autor:
Jintang Du1, Yeyun Zhou2, Xiaoyang Su1, Jiu Jiu Yu3, Saba Khan1, Hong Jiang1, Jungwoo Kim1, Jimin Woo1, Jun Huyn Kim1, Choi, Brian Hyun1, Bin He1, Wei Chen4, Sheng Zhang4, Cerione, Richard A.1,5, Auwerx, Johan3, Quan Hao2,6, Hening Lin1
Publikováno v:
Science. 11/11/2011, Vol. 334 Issue 6057, p806-809. 4p.
Publikováno v:
Human Molecular Genetics. 22:5276-5287
Myotonic dystrophy type 1 (DM1) is an inherited dominant muscular dystrophy caused by expanded CTG·CAG triplet repeats in the 3' untranslated region of the DMPK1 gene, which produces a toxic gain-of-function CUG RNA. It has been shown that the sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe51478477ce266f9c2accdc384ad23
https://doi.org/10.1093/hmg/ddt386
https://doi.org/10.1093/hmg/ddt386
Autor:
Yong Li, Chun-Hui Yu, Hiroshi Nakanishi, Yan-Mei Li, Jintang Du, Wei-Hui Wu, Yufen Zhao, Peng Lei, Lian-Xiu Zhou
Publikováno v:
FEBS Journal. 274:5012-5020
Phosphorylation of tau protein modulates both its physiological role and its aggregation into paired helical fragments, as observed in Alzheimer's diseased neurons. It is of fundamental importance to study paired helical fragment formation and its mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c980d6b738a2c6a025b13bfe4167efa
https://doi.org/10.1111/j.1742-4658.2007.06018.x
https://doi.org/10.1111/j.1742-4658.2007.06018.x
Autor:
Jaime I. Davila, Eric D. Wieben, Sanjay V. Patel, Joel M. Gottesfeld, Xiaojia Tang, Elisabetta Soragni, Jean-Pierre A. Kocher, Ross A. Aleff, Keith H. Baratz, Jinfu Nie, Jintang Du, Krishna R. Kalari
Publikováno v:
The Journal of Biological Chemistry
Background: Expansion of intronic (CTG·CAG)n repeats in TCF4 is found in most Fuchs endothelial corneal dystrophy (FECD) patients. Results: RNA foci co-localizing with the splicing factor MBNL1 are found in FECD cells, and changes in mRNA splicing o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d7f77b48e8dfbeecfc147600b9a17c8
https://pubmed.ncbi.nlm.nih.gov/25593321
https://pubmed.ncbi.nlm.nih.gov/25593321
Autor:
Tadashi Nemoto, Yufen Zhao, Huadong Liu, Qing-Feng Ma, Jintang Du, Yan-Mei Li, Hiroshi Nakanishi, Kenji Kanazawa
Publikováno v:
Peptides. 27:841-849
We have previously reported the copper binding properties of R3 peptide (residues 318–335: VTSKCGSLGNIHHKPGGG, according to the longest tau protein) derived from the third repeat microtubule-binding domain of water-soluble tau protein. In this work
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd9bc4d513241429b95f5092756e7e9
https://doi.org/10.1016/j.peptides.2005.09.002
https://doi.org/10.1016/j.peptides.2005.09.002
Publikováno v:
International Journal of Peptide Research and Therapeutics. 12:187-193
Lysine methylation within the N-terminal tail region of histones is associated with various biological processes ranging from transcriptional regulation to epigenetic silencing. In order to investigate biological functions of methylation, specific ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e6ba80abafb73ee40bdc9dc95f4045a
https://doi.org/10.1007/s10989-005-9006-z
https://doi.org/10.1007/s10989-005-9006-z