Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jinsen Li"'
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Benign paroxysmal positional vertigo (BPPV) is a prevalent form of vertigo that necessitates a skilled physician to diagnose by observing the nystagmus and vertigo resulting from specific changes in the patient’s position. In th
Externí odkaz:
https://doaj.org/article/286312049ccd4eb7925a0dab1b570aba
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Understanding the mechanisms of protein-DNA binding is critical in comprehending gene regulation. Three-dimensional DNA structure, also described as DNA shape, plays a key role in these mechanisms. In this study, we present a deep learning-b
Externí odkaz:
https://doaj.org/article/a235354de6824288b14bf09b3d23e2ce
Autor:
Clare S. K. Lee, Ming Fung Cheung, Jinsen Li, Yongqian Zhao, Wai Hei Lam, Vincy Ho, Remo Rohs, Yuanliang Zhai, Danny Leung, Bik-Kwoon Tye
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
In most model yeast species the Origin Recognition Complex (ORC) binds defined and species-specific base sequences while in humans what determines the binding appears to be more complex. Here the authors reveal that the yeast’s ORC complex binding
Externí odkaz:
https://doaj.org/article/f4ce881c9d4e4808a3ce45ff1501fdd0
Publikováno v:
Applied Intelligence. 53:10879-10892
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::079a5dba6756bb713eaeb390ab60bc88
https://doi.org/10.1007/s10489-022-04070-6
https://doi.org/10.1007/s10489-022-04070-6
Publikováno v:
Biophysical journal. 121(20)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eeff4eb2949ac5e4f8ce8b9c0c264ae
https://pubmed.ncbi.nlm.nih.gov/35978548
https://pubmed.ncbi.nlm.nih.gov/35978548
Publikováno v:
2021 40th Chinese Control Conference (CCC).
This paper proposes a set of automated garbage sorting system and designs the garbage sorting algorithm based on the neural network and YOLO algorithm. To realize the detection of books, cans, plastic bottles, and glass bottles, we design a feature e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d6c02c19e103c05bbaa2cfab7914c8
https://doi.org/10.23919/ccc52363.2021.9549336
https://doi.org/10.23919/ccc52363.2021.9549336
Autor:
Yongqian Zhao, Clare S. K. Lee, Vincy Ho, Ming Fung Cheung, Remo Rohs, Yuanliang Zhai, Wai Hei Lam, Bik Kwoon Tye, Danny Leung, Jinsen Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
The Origin Recognition Complex (ORC) is an evolutionarily conserved six-subunit protein complex that binds specific sites at many locations to coordinately replicate the entire eukaryote genome. Though highly conserved in structure, ORC’s selectivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2942bba80adbe394679b71cd159992db
https://doi.org/10.1038/s41467-020-20277-y
https://doi.org/10.1038/s41467-020-20277-y
Publikováno v:
Nucleic Acids Research
Uncovering the mechanisms that affect the binding specificity of transcription factors (TFs) is critical for understanding the principles of gene regulation. Although sequence-based models have been used successfully to predict TF binding specificiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b148806aa27cbf9ffda75920ed86f1
Autor:
Rong Li, X. Sunney Xie, Liying Yan, Fuchou Tang, Wei Fan, Jinsen Li, Yu Hou, Jie Qiao, Ying Lian, Jin Huang, Liya Xu
Publikováno v:
Cell. 155(7):1492-1506
SummarySingle-cell genome analyses of human oocytes are important for meiosis research and preimplantation genomic screening. However, the nonuniformity of single-cell whole-genome amplification hindered its use. Here, we demonstrate genome analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a4ff9420a171d586ea53133389453f
Publikováno v:
Cell Insight, Vol 2, Iss 3, Pp 100092- (2023)
Proteolysis targeting chimera (PROTAC) degradation of pathogenic proteins by hijacking of the ubiquitin-proteasome-system has become a promising strategy in drug design. The overwhelming advantages of PROTAC technology have ensured a rapid and wide u
Externí odkaz:
https://doaj.org/article/df2437e043c9498a8d0019586d0ffaa6