Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jinsam You"'
Autor:
Byounghoon Hwang, Funita P Phan, Kevin McCool, Eun Young Choi, Jinsam You, Adam Johnson, Anjon Audhya, Shigeki Miyamoto
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0116374 (2015)
NF-κB essential modulator, NEMO, plays a key role in canonical NF-κB signaling induced by a variety of stimuli, including cytokines and genotoxic agents. To dissect the different biochemical and functional roles of NEMO in NF-κB signaling, various
Externí odkaz:
https://doaj.org/article/05d91848dbae45c4b304513bc3498be0
Autor:
Sharon K Huang, Marlene M Darfler, Michael B Nicholl, Jinsam You, Kerry G Bemis, Tony J Tegeler, Mu Wang, Jean-Pierre Wery, Kelly K Chong, Linhda Nguyen, Richard A Scolyer, Dave S B Hoon
Publikováno v:
PLoS ONE, Vol 4, Iss 2, p e4430 (2009)
Melanoma metastasis status is highly associated with the overall survival of patients; yet, little is known about proteomic changes during melanoma tumor progression. To better understand the changes in protein expression involved in melanoma progres
Externí odkaz:
https://doaj.org/article/fe32f607643c41379704caeebf0e7114
Autor:
Jinsam You, Kyla Driscoll, Jeffrey A. Willy, Laurent Malherbe, Anja Koester, Derrick R. Witcher, Rikke B. Holmgaard, Guilherme Rocha, Jiabin Qiu, Nada S Alakhras, David Schaer
Publikováno v:
mAbs. 10(6)
Immunomodulatory monoclonal IgG1 antibodies developed for cancer and autoimmune disease have an inherent risk of systemic release of pro-inflammatory cytokines. In vitro cytokine release assays are currently used to predict cytokine release syndrome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b1374f97c8b8f41de77e924d67ad7e
https://pubmed.ncbi.nlm.nih.gov/29953319
https://pubmed.ncbi.nlm.nih.gov/29953319
Autor:
Jesus A. Gutierrez, Valentina Gelfanova, Robert W. Siegel, Richard E. Higgs, Chloe N. Poston, Michael D. Knierman, John E. Hale, Jinsam You
Publikováno v:
Journal of the American Society for Mass Spectrometry. 25:1228-1236
De novo sequencing by mass spectrometry (MS) allows for the determination of the complete amino acid (AA) sequence of a given protein based on the mass difference of detected ions from MS/MS fragmentation spectra. The technique relies on obtaining sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d27c03d273853c7e629371a72edd3eb
https://doi.org/10.1007/s13361-014-0892-1
https://doi.org/10.1007/s13361-014-0892-1
Autor:
Jong Won Kim1, Jinsam You1 jinyou@iupui.edu
Publikováno v:
International Journal of Proteomics. 2013, p1-8. 8p.
Autor:
Jinsam You, Jong Won Kim
Publikováno v:
International Journal of Proteomics
The utility of mass spectrometry-(MS-) based proteomic platforms and their clinical applications have become an emerging field in proteomics in recent years. Owing to its selectivity and sensitivity, MS has become a key technological platform in prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6463382dcde3357eb568d1b18a04d6a1
https://doi.org/10.1155/2013/701247
https://doi.org/10.1155/2013/701247
Publikováno v:
Journal of Biological Chemistry. 285:24466-24476
Mammalian Wdr82 is a regulatory component of the Setd1a and Setd1b histone H3-lysine 4 methyltransferase complexes and is implicated in the tethering of Setd1 complexes to transcriptional start sites of active genes. In the studies reported here, imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d356126c33b482ef4ca7664ca8dae1c
https://doi.org/10.1074/jbc.m110.109801
https://doi.org/10.1074/jbc.m110.109801
Publikováno v:
Briefings in Functional Genomics and Proteomics. 7:329-339
Major technological advances have made proteomics an extremely active field for biomarker discovery and validation in recent years. These improvements have lead to an increased emphasis on larger scale, faster and more efficient methods for protein b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9882e8a5faaa455c44c98b54c2a8b94f
https://doi.org/10.1093/bfgp/eln031
https://doi.org/10.1093/bfgp/eln031
Autor:
Connie S. Powers, John E. Hale, Yanfei L. Ma, Anita K. Harvey, Bomie Han, Jinsam You, Masahiko Sato, L. V. Hale, Andrew G. Geiser, Marci Copeland
Publikováno v:
Journal of Proteome Research. 6:4218-4229
Type-I procollagen aminoterminal propeptide (PINP) is a useful biomarker for bone formation activity that is used to monitor treatment of bone disorders including osteoporosis. Studies with human patients under long-term therapy for osteoporosis by d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b531860454777eed165b56d0d55acf0b
https://doi.org/10.1021/pr070288s
https://doi.org/10.1021/pr070288s
Autor:
James R. Ludwig, Dawn P. G. Fitzpatrick, Jinsam You, Mu Wang, Jean-Pierre Wery, Kerry G. Bemis
Publikováno v:
PROTEOMICS – Clinical Applications. 1:246-263
Platinum-based chemotherapy, such as cisplatin, is the primary treatment for ovarian cancer. However, drug resistance has become a major impediment to the successful treatment of ovarian cancer. To date, the molecular mechanisms of resistance to plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d4f35d71f43e2b6de3343e19d12416
https://doi.org/10.1002/prca.200600768
https://doi.org/10.1002/prca.200600768