Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Jinsaku Sakakibara"'
Autor:
Fumiko Ohtsu, Chiyo Mori, Nobuyuki Goto, Jinsaku Sakakibara, Kouichi Tanabe, Takamasa Sakai, Reiko Yano
Publikováno v:
Journal of Pharmacovigilance.
Background: Ritodrine is a drug used for threatened premature labor. The severe adverse drug reactions associated with ritodrine are known to be pneumonedema, leukopenia, and rhabdomyolysis, but there have been few investigations on the risk factors.
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 38:67-77
Publikováno v:
YAKUGAKU ZASSHI. 131:139-152
The present study investigated risk factors and subjective symptoms associated with drug-induced leucopenia. We selected 248 patients with drug-induced leucopenia from the Case Reports of Adverse Drug Reactions and Poisoning Information System (CARPI
Autor:
Michio Yajima, Norio Kawai, Naohisa Ishikawa, Kunihiro Miyazeki, Yoshihiro Hotta, Xiuli Lu, Jinsaku Sakakibara, Hajime Mizukami, Tatsuya Muto, Akito Nagatsu, Wei Liu, Chihiro Narumiya
Publikováno v:
Molecular and Cellular Biochemistry. 238:151-162
N-(p-Coumaroyl)serotonin (C) and N-feruroylserotonin (F) with antioxidative activity are present in safflower oil. The protective effects of C and F were investigated in perfused guinea-pig Langendorff hearts subjected to ischemia and reperfusion. Ch
Publikováno v:
Tetrahedron. 57:3005-3012
Monensin (1), an ionophore antibiotic agent, was converted to 25-carboxymonensin (2) and 7-O-substituted-25-carboxyl derivatives (3a–d), which have two carboxyl groups at both ends of the molecule. Ca2+ ion transport activity of the dicarboxylic mo
Autor:
Naoyoshi Yatsuzuka, Emi Takeichi, Taisei Ueda, Kumiko Okada, Jinsaku Sakakibara, Hiromi Segi, Shin-ichi Nagai
Publikováno v:
Journal of Heterocyclic Chemistry. 38:141-145
Oxidation of 7,8-diaminotheophylline (1) with lead tetraacetate in refluxing toluene gave a mixture of 3-amino-5,7-dimethylpyrimido[4,5-e][1,2,4]triazine-6,8-dione (2) and 6-cyanoimino-5-diazo-1,3-dimethylpyrimidine-2,4-dione (4). The latter was tran
Publikováno v:
Chemical and Pharmaceutical Bulletin. 49:711-715
The C-26 modified monensin derivatives, 26-O-benzoylmonensin (3), 26-O-benzylmonensin (4) and 26-phenylaminomonensin (5) were prepared from monensin (1). Na+ ion transport activity through biological membrane and antibacterial activity of 3-5 were ev
Publikováno v:
Journal of Heterocyclic Chemistry. 37:1269-1272
Novel heterocycles [1,2,5]selenadiazolo[3,4-e][1,4]diazepines 3a-c, [1,2,5]thiadiazolo[3,4-e]-[1,4]diazepines 7a-c, [1,2,5]selenadiazolo[3,4-e][1,4]oxaepines 4a,b, [1,2,5]thiadiazolo[3,4-e]-[1,4]oxazepines 9a-c and [1,2,5]selena(or thia)diazolo[3,4-c
Autor:
Rie Tanaka, Yukio Ogihara, Hajime Mizukami, Akito Nagatsu, Jinsaku Sakakibara, Masayo Hashimoto
Publikováno v:
Tetrahedron Letters. 41:2629-2632
Ionophore antibiotic monensin ( 1 ) was converted to 25-carboxylmonensin ( 3 ), which has two carboxyl groups at both ends of the molecule. Ca 2+ ion transport activity of 25-carboxylmonensin ( 3 ) was evaluated by the CHCl 3 liquid membrane method,
Autor:
Harukuni Tokuda, Hoyoku Nishino, Harumi Okuyama, Hajime Mizukami, Akito Nagatsu, Jinsaku Sakakibara, Hui Zhang
Publikováno v:
Natural Product Letters. 14:153-158
Tyrosinase inhibitory and anti-tumor promoting activities of 14 compounds isolated from safflower and cotton oil cakes were evaluated together with the two genins of glycosides, trachorogenin (8a) and quercetin (12a). Catechin (11) and quercetin (12a