Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jinrun Xu"'
Autor:
Yu Chen, Qingfan Yang, Jinrun Xu, Liyao Tang, Yan Zhang, Fukuan Du, Yueshui Zhao, Xu Wu, Mingxing Li, Jing Shen, Ruilin Ding, Hongying Cao, Wanping Li, Xiaobing Li, Meijuan Chen, Zhigui Wu, Chi Hin Cho, Yu Du, Qinglian Wen, Zhangang Xiao
Publikováno v:
Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 204-223 (2022)
Proteolysis targeting chimera (PROTAC) presents a powerful strategy for targeted protein degradation (TPD). The heterobifunctional PROTAC molecule consists of an E3 ligase ligand covalently linked to a protein of interest (POI) via a linker. PROTAC c
Externí odkaz:
https://doaj.org/article/bf708ce6e296413ebb56d0b8ba2f42f4
Publikováno v:
Journal of Marine Science and Engineering, Vol 12, Iss 1, p 13 (2023)
The accurate estimation of the spatial and temporal distribution of chlorophyll-a (Chl-a) concentrations in the South China Sea (SCS) is crucial for understanding marine ecosystem dynamics and water quality assessment. However, the challenge of missi
Externí odkaz:
https://doaj.org/article/ed96f0bdb89c4567ac240e231158c88f
Autor:
Yu Chen, Fukuan Du, Liyao Tang, Jinrun Xu, Yueshui Zhao, Xu Wu, Mingxing Li, Jing Shen, Qinglian Wen, Chi Hin Cho, Zhangang Xiao
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 400-416 (2022)
Carborane is a carbon-boron molecular cluster that can be viewed as a 3D analog of benzene. It features special physical and chemical properties, and thus has the potential to serve as a new type of pharmacophore for drug design and discovery. Based
Externí odkaz:
https://doaj.org/article/e5c28f0d79564bdabbee8f4941a4f657
Autor:
Liyao Tang, Yan Zhang, Jinrun Xu, Qingfan Yang, Fukuan Du, Xu Wu, Mingxing Li, Jing Shen, Shuai Deng, Yueshui Zhao, Zhangang Xiao, Yu Chen
Publikováno v:
Molecules, Vol 28, Iss 3, p 1414 (2023)
Efficient and mild synthetic routes for bioactive natural product derivatives are of current interest for drug discovery. Herein, on the basis of the pharmacophore hybrid strategy, we report a two-step protocol to obtain a series of structurally nove
Externí odkaz:
https://doaj.org/article/ad2918875594452b896216327856d536