Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Jinrong YANG"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectiveBiological studies have elucidated that phosphoglycerate dehydrogenase (PHGDH) is the rate-limiting enzyme in the serine synthesis pathway in humans that is abnormally expressed in numerous cancers. Inhibition of the PHGDH activity is though
Externí odkaz:
https://doaj.org/article/f0ebabd0fb9c407c804bb64209dc4023
Autor:
Jinrong Yang, Jie Yu, Yaoling Wang, Man Liao, Yingying Ji, Xiang Li, Xuechun Wang, Jun Chen, Benling Qi, Fan Yang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract This study aims to develop and validate nomogram models utilizing clinical and thoracic aorta imaging factors to assess the risk of hypertension for lung cancer screening cohorts. We included 804 patients and collected baseline clinical data
Externí odkaz:
https://doaj.org/article/2c8299ab82f84ef5ba7324ecd1e6f534
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-30 (2023)
Abstract Natural killer (NK) cells, a unique component of the innate immune system, are inherent killers of stressed and transformed cells. Based on their potent capacity to kill cancer cells and good tolerance of healthy cells, NK cells have been su
Externí odkaz:
https://doaj.org/article/739951d7d0f748cb89aa9f841331f3c9
Autor:
Miao Dong, Dazhuang Wang, Jinrong Yang, Pingping Sun, Weilu Ding, Jianxin Yang, Jinwu Yan, Weijie Chi
Publikováno v:
Smart Molecules, Vol 1, Iss 3, Pp n/a-n/a (2023)
Abstract Deep understanding of the fluorescence quenching mechanisms of probes plays a crucial role in developing their practical applications. The fluorescence quenching mechanism of hydrazine‐based fluorescence probes needs to be clarified up to
Externí odkaz:
https://doaj.org/article/b90e4ec6bf6c47e89ea168fd541deb4e
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundWhether the airway is involved in the pathogenesis of interstitial lung abnormalities (ILA) is not well understood. Also the impact of ILA on lung function in COPD patients remains controversial. We aimed to assess the quantitative CT measu
Externí odkaz:
https://doaj.org/article/76705f6a44ca4a0f824467c1a7f6d2de
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 9, Iss , Pp 100107- (2023)
The accumulation, processing and toxicity of Aβ can be affected by interacting with transthyretin (TTR). We obtained 31 compounds with different structures by virtual screening based on protein structure. Among them, compound 11 inhibited acid-induc
Externí odkaz:
https://doaj.org/article/f82d3b9feb514e3cb5798f9b93d8488c
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-40 (2023)
Abstract Hematologic malignancies are one of the most common cancers, and the incidence has been rising in recent decades. The clinical and molecular features of hematologic malignancies are highly heterogenous, and some hematologic malignancies are
Externí odkaz:
https://doaj.org/article/b7990865ff6a4ff6916442fc33863a4f
Publikováno v:
IET Computer Vision, Vol 16, Iss 6, Pp 556-566 (2022)
Abstract Most anchor‐based detectors use intersection over union (IoU) to assign targets to anchors during training. However, IoU did not pay enough attention to the proximity of the anchor's centre to the centre of the truth box, resulting in two
Externí odkaz:
https://doaj.org/article/b5644feb66194b9e8b6f7dc07ce0cf30
Publikováno v:
Buildings, Vol 13, Iss 11, p 2764 (2023)
The dynamic response of a radio telescope structure under wind load excitation significantly impacts the accuracy of signal reception. To address this issue, this study established a parametric finite element model of a radio telescope to simulate it
Externí odkaz:
https://doaj.org/article/b1de1e7ae24b4dbf933c4cd46398d881
Treatment attrition rates and relevant risk factors in multiple myeloma: A real-world study in China
Autor:
Wenjiao Tang, Jinrong Yang, Yan Li, Li Zhang, He Li, Jie Wang, Yi Liao, Chunlan Zhang, Ying Qu, Yuhuan Zheng, Ting Niu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: For multiple myeloma (MM), the proportions of patients reaching the subsequent line of therapy (LOT) decline gradually and real-world data describing the attrition rates of LOT in Chinese MM were limited. Herein, we investigated the attri
Externí odkaz:
https://doaj.org/article/d86c2b53208544f7a3de59ea8e8a1b1c