Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jinqin Chen"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Recently, targeted therapy and immunotherapy have emerged as effective treatment options for non-small cell lung cancer (NSCLC). This progress has been facilitated by the rapid development of diagnostic and therapeutic technologies and the continuous
Externí odkaz:
https://doaj.org/article/15acd1ee8af3412f9c2fc240cacb5459
Autor:
Jinqin Chen, Xinhong Liu, Shuo Yu, Jia Liu, Rongfang Chen, Yunxiao Zhang, Ling Jiang, Qiuyun Dai
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2685-2693 (2021)
ω-Conotoxins inhibit N-type voltage-gated calcium (CaV2.2) channels and exhibit efficacy in attenuating neuropathic pain but have a low therapeutic index. Here, we synthesized and characterized a novel ω-conotoxin, Bu8 from Conus bullatus, which co
Externí odkaz:
https://doaj.org/article/a70fd78ef1424fb7afa9c9006cddbd6a
Autor:
Shuo Yu, Yumeng Li, Jinqin Chen, Yue Zhang, Xinling Tao, Qiuyun Dai, Yutian Wang, Shupeng Li, Mingxin Dong
Publikováno v:
Marine Drugs, Vol 17, Iss 5, p 286 (2019)
As the first in a new class of non-opioid drugs, ω-Conotoxin MVIIA was approved for the management of severe chronic pains in patients who are unresponsive to opioid therapy. Unfortunately, clinical application of MVIIA is severely limited due to it
Externí odkaz:
https://doaj.org/article/80e3f1a8ca76481fa9b16cbc9207dbac
Autor:
Jinqin Chen, Li Liang, Huying Ning, Fengtao Cai, Zhuguo Liu, Longxiao Zhang, Liangyi Zhou, Qiuyun Dai
Publikováno v:
Marine Drugs, Vol 16, Iss 4, p 112 (2018)
α-Conotoxins (α-CTxs) are small peptides composed of 11 to 20 amino acid residues with two disulfide bridges. Most of them potently and selectively target nicotinic acetylcholine receptor (nAChR) subtypes, and a few were found to inhibit the GABAB
Externí odkaz:
https://doaj.org/article/46615dcfcbfe440b89f3956c0c9bb41f
Autor:
Yunxiao Zhang, Qiuyun Dai, Jinqin Chen, Shuo Yu, Rongfang Chen, Jia Liu, Ling Jiang, Xinhong Liu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2685-2693 (2021)
ω-Conotoxins inhibit N-type voltage-gated calcium (CaV2.2) channels and exhibit efficacy in attenuating neuropathic pain but have a low therapeutic index. Here, we synthesized and characterized a novel ω-conotoxin, Bu8 from Conus bullatus, which co
Publikováno v:
Oncology Letters
Long non-coding RNA SLC25A25 antisense RNA 1 (SLC25A25-AS1) exerts antitumour activity in colorectal cancer. The present study investigated whether SLC25A25-AS1 is implicated in the aggressiveness of non-small cell lung cancer (NSCLC) and the possibl
Background: To date, long intergenic nonprotein coding RNA 1132 (LINC01132) expression in epithelial ovarian cancer (EOC) and the underlying mechanisms have not been explored. In this study, we measured LINC01132 expression in EOC and assessed the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b53c032ebe5cc63fac2bef8ea489329c
https://doi.org/10.21203/rs.3.rs-219226/v1
https://doi.org/10.21203/rs.3.rs-219226/v1
Publikováno v:
International Journal of Molecular Medicine
To date, the role of lncRNA long intergenic non-protein-coding RNA 1132 (LINC01132) expression in epithelial ovarian cancer (EOC) has not been explored. Thus, LINC01132 expression in EOC was assessed and the regulatory activity of LINC01132 on the ma
Autor:
Jinqin, Chen, Xinhong, Liu, Shuo, Yu, Jia, Liu, Rongfang, Chen, Yunxiao, Zhang, Ling, Jiang, Qiuyun, Dai
Publikováno v:
Acta Pharmaceutica Sinica. B
ω-Conotoxins inhibit N-type voltage-gated calcium (CaV2.2) channels and exhibit efficacy in attenuating neuropathic pain but have a low therapeutic index. Here, we synthesized and characterized a novel ω-conotoxin, Bu8 from Conus bullatus, which co
Publikováno v:
BioMed Research International, Vol 2017 (2017)
BioMed Research International
BioMed Research International
Atherosclerosis is an important pathological condition which is accompanied by a vascular smooth muscle cell (VSMC) phenotype switch toward a synthetic phenotype. As an acute-phase protein, Serum Amyloid A (SAA) is thought to have a close relationshi