Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jinqian, Liu"'
Autor:
Shuo Wang, Jinqian Liu, Jing Dong, Zongqiang Fan, Fugui Wang, Ping Wu, Xiaojing Li, Ruirui Kou, Fang Chen
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Allyl methyl trisulfide (AMTS) is one major lipid-soluble organosulfur compound of garlic. Previous studies have reported the potential therapeutic effect of garlic on acute lung injury (ALI) or its severe condition acute respiratory distress syndrom
Externí odkaz:
https://doaj.org/article/ecec6fb67a7e40b79b6a8aceef3a1dbd
Autor:
Jinqian, Liu, Wen, Wang, Changqing, Wang, Li, Zhang, Xueliang, Zhang, Shicong, Liu, Yunhua, Xu, Hailin, Wang, Qing, Dai, Chun, Liu, Xinghai, Wang, Zhengyu, Yuan, Mikhail F, Gordeev
Publikováno v:
ACS medicinal chemistry letters. 13(7)
New oral antibiotic contezolid (CZD) is effective against Gram-positive infections but unsuitable for intravenous (IV) administration due to its modest solubility. To address the medical need for an IV form of CZD, its isoxazol-3-yl phosphoramidate d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c562c941d781c7251a4f6489b80d485
https://pubmed.ncbi.nlm.nih.gov/35859881
https://pubmed.ncbi.nlm.nih.gov/35859881
Autor:
Jinqian Liu, Wen Wang, Changqing Wang, Li Zhang, Xueliang Zhang, Shicong Liu, Yunhua Xu, Hailin Wang, Qing Dai, Chun Liu, Xinghai Wang, Zhengyu Yuan, Mikhail F. Gordeev
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1030-1035
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a0a2dfad2eb5c880c6794214816ad22
https://doi.org/10.1021/acsmedchemlett.2c00191
https://doi.org/10.1021/acsmedchemlett.2c00191
Publikováno v:
Chemical Research in Toxicology. 34:1348-1354
Linezolid, the principal oxazolidinone antibiotic for therapy of Gram-positive infections, is limited by its myelosuppression and monoamine oxidase (MAO) inhibition, with the latter manifested as serotonergic neurotoxicity. The oral oxazolidinone con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a6d8a841a0a32086142ebf7984cd1c
https://doi.org/10.1021/acs.chemrestox.0c00524
https://doi.org/10.1021/acs.chemrestox.0c00524
Publikováno v:
Toxicology. 488:153487
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df282353532feee91b53ea29c94038e0
https://doi.org/10.1016/j.tox.2023.153487
https://doi.org/10.1016/j.tox.2023.153487
Publikováno v:
ChemElectroChem. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8fb4a51327dcbc1c6a835ff2df19f00
https://doi.org/10.1002/celc.202200039
https://doi.org/10.1002/celc.202200039
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c551fb232ccbafc3f6db8acc21925d01
https://doi.org/10.2139/ssrn.3993329
https://doi.org/10.2139/ssrn.3993329
Autor:
Jian Luo, Jinqian Liu, Jane Zhang, Jonathan B. Houze, Todd J. Kohn, Run Zhuang, Simon Wong, Michael D. Bartberger, Zhihua Ma, Daniel C.-H. Lin, Yingcai Wang, George Tonn, Jiwen Jim Liu, Frank Li, Liusheng Zhu, An-Rong Li, Julio C. Medina, Rajiv Sharma
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:15-20
As a follow-up to the GPR40 agonist AMG 837, which was evaluated in clinical trials for the treatment of type II diabetes, further optimization led to the discovery of AM-3189 (13k). AM-3189 is representative of a new class of compounds with minimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd9f66e7e014e23d509ba4642700f1c
https://doi.org/10.1016/j.bmcl.2015.11.050
https://doi.org/10.1016/j.bmcl.2015.11.050
Autor:
Deyou LIU, Yangang LIU, Lijuan LIU, Xiaomei CUI, Zhaotang SHEN, Jinqian LIU, Xiugang YU, Zhouliang WANG, Shengfeng ZHANG, Qingquan MU, Xiushan ZHAO
Publikováno v:
Asian Agricultural Research; Jun2021, Vol. 13 Issue 6, p54-58, 5p
Autor:
Liang Li, Mikhail Fedorovich Gordeev, Zhengyu Yuan, Jinqian Liu, Hong Yuan, Chen Li, Dafang Zhong, Jian Meng, Xiaoyan Chen, Jialan Zhou, Cen Xie
Publikováno v:
Drug Metabolism and Disposition. 43:646-659
MRX-I is an analog of linezolid containing a 2,3-dihydropyridin-4-one (DHPO) ring rather than a morpholine ring. Our objectives were to characterize the major metabolic pathways of MRX-I in humans and clarify the mechanism underlying the oxidative ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889acef6dbd1b3c43e8ba0a44166b4e9
https://doi.org/10.1124/dmd.114.061747
https://doi.org/10.1124/dmd.114.061747