Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jinny Xuemeng Zhang"'
Autor:
Lucia Ruojia Wu, Peng Dai, Michael Xiangjiang Wang, Sherry Xi Chen, Evan N. Cohen, Gitanjali Jayachandran, Jinny Xuemeng Zhang, Angela V. Serrano, Nina Guanyi Xie, Naoto T. Ueno, James M. Reuben, Carlos H. Barcenas, David Yu Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Highly multiplexed ddPCR for sensitive nucleic acid quantitation remains challenging due to limited fluorescence channels. Here the authors report quantitative amplicon sequencing (QASeq), a PCR-based molecular barcoding NGS approach which is compati
Externí odkaz:
https://doaj.org/article/4d7f4e4784404a73a971f604e13766e8
Autor:
Peng Dai, Lucia Ruojia Wu, Sherry Xi Chen, Michael Xiangjiang Wang, Lauren Yuxuan Cheng, Jinny Xuemeng Zhang, Pengying Hao, Weijie Yao, Jabra Zarka, Ghayas C. Issa, Lawrence Kwong, David Yu Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Quantification of rare somatic mutations is essential for basic research and translational applications. Here the authors present Quantitative Blocker Displacement Amplification allowing for accurate detection of mutations below 0.01% VAF.
Externí odkaz:
https://doaj.org/article/fa41048a06034246b3822d3ae3d81bf0
Autor:
Kerou Zhang, Ping Song, Peng Dai, Jinny Xuemeng Zhang, Lucia Ruojia Wu, Lauren Yuxuan Cheng, Alessandro Pinto, Lawrence Kwong, Karina Cabrera, Ruoxin Wen, David Yu Zhang
Publikováno v:
ACS sensors. 7(4)
Molecular detection of disease-associated mutations, especially those with low abundance, is essential for academic research and clinical diagnosis. Certain variant detection methods reach satisfactory sensitivity and specificity in detecting rare mu
Autor:
Lucia Ruojia Wu, Peng Dai, Michael Xiangjiang Wang, Sherry Xi Chen, Evan N. Cohen, Gitanjali Jayachandran, Jinny Xuemeng Zhang, Angela V. Serrano, Nina Guanyi Xie, Naoto T. Ueno, James M. Reuben, Carlos H. Barcenas, David Yu Zhang
Publikováno v:
Nature communications. 13(1)
Current gold standard for absolute quantitation of a specific DNA sequence is droplet digital PCR (ddPCR), which has been applied to copy number variation (CNV) detection. However, the number of quantitation modules in ddPCR is limited by fluorescenc