Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Jinny Kim"'
Autor:
Osman Dadas, Joel D. Allen, Sarah L. Buchan, Jinny Kim, H. T. Claude Chan, C. Ian Mockridge, Patrick J. Duriez, Anne Rogel, Max Crispin, Aymen Al-Shamkhani
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionT cell expressed CD27 provides costimulation upon binding to inducible membrane expressed trimeric CD70 and is required for protective CD8 T cell responses. CD27 agonists could therefore be used to bolster cellular vaccines and anti-tumou
Externí odkaz:
https://doaj.org/article/1b431c0777aa4151a8bb65c2e1304139
Autor:
Xiaojie Yu, Sonya James, James H. Felce, Blanka Kellermayer, David A. Johnston, H. T. Claude Chan, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Yasunori Watanabe, Max Crispin, Ruth R. French, Patrick J. Duriez, Leon R. Douglas, Martin J. Glennie, Mark S. Cragg
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Yu et al examined a panel of both experimental and clinically-relevant TNF agonists in order to advance our understanding of the mechanisms underlying their varying activities and anti-tumor responses. They demonstrated that agonists with greater act
Externí odkaz:
https://doaj.org/article/497b996aa1574d6a946f5ee6787fec3f
Autor:
C Ian Mockridge, H T Claude Chan, Mark S Cragg, Jinny Kim, Tatyana Inzhelevskaya, Jane E Willoughby, Julia Moreno-Vicente, Martin C Taylor, Steven G Booth, Vikki L English, Emily L Williams, Christine A Penfold, Juliet C Gray, Stephen A Beers
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/0d95105e612946869ce83db4c68db191
Autor:
C Ian Mockridge, Kerry L Cox, Martin J Glennie, Mark S Cragg, Monika Semmrich, Linda Mårtensson, Ingrid Teige, Jordana Griffiths, Khiyam Hussain, Hannah L Smith, Theodore Sanders, Jinny Kim, Tatyana Inzhelevskaya, Chris A Penfold, Alison L Tutt, HT Claude Chan, Vikki English, Ruth F French, Aymen Al-Shamkhani, Bjorn L Frendeus, Jane E Willoughby
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Previous data suggests that anti-OX40 mAb can elicit anti-tumor effects in mice through deletion of Tregs. However, OX40 also has powerful costimulatory effects on T cells which could evoke therapeutic responses. Human trials with anti-OX4
Externí odkaz:
https://doaj.org/article/86d9cb4f413b4935a92592aca78649b9
Autor:
Xiaojie Yu, Christian M. Orr, H. T. Claude Chan, Sonya James, Christine A. Penfold, Jinny Kim, Tatyana Inzhelevskaya, C. Ian Mockridge, Kerry L. Cox, Jonathan W. Essex, Ivo Tews, Martin J. Glennie, Mark S. Cragg
Antibody responses during infection and vaccination typically undergo affinity maturation to achieve high-affinity binding for efficient neutralization of pathogens1,2. Similarly, high affinity is routinely the goal for therapeutic antibody generatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3413a611d84ceac2eb9f01db8758a17
https://eprints.soton.ac.uk/475620/
https://eprints.soton.ac.uk/475620/
Autor:
Mark S. Cragg, H.T. Claude Chan, Max Crispin, David A. Johnston, Martin J. Glennie, James H Felce, Leon Douglas, C. Ian Mockridge, Sonya James, Jinny Kim, Xiaojie Yu, Ruth R. French, Christine A. Penfold, Tatyana Inzhelevskaya, Yasunori Watanabe, Patrick J. Duriez, Blanka Kellermayer
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology
Monoclonal antibodies (mAb) and natural ligands targeting costimulatory tumor necrosis factor receptors (TNFR) exhibit a wide range of agonistic activities and antitumor responses. The mechanisms underlying these differential agonistic activities rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b17224ce36635b86b6bad1a9401509
https://doaj.org/article/497b996aa1574d6a946f5ee6787fec3f
https://doaj.org/article/497b996aa1574d6a946f5ee6787fec3f
Autor:
Jinny Kim, Ulrich Dahn
Publikováno v:
ATZ - Automobiltechnische Zeitschrift. 122:50-53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f60dc0308fa85d5e36509d8472a18c6a
https://doi.org/10.1007/s35148-020-0232-7
https://doi.org/10.1007/s35148-020-0232-7
Autor:
Jinny Kim, Ulrich Dahn
Publikováno v:
ATZ worldwide. 122:50-53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aae23e99311b2d4d8dd79ade2e3b9545
https://doi.org/10.1007/s38311-020-0218-9
https://doi.org/10.1007/s38311-020-0218-9
Autor:
Julia Moreno-Vicente, Jane E Willoughby, Martin C Taylor, Steven G Booth, Vikki L English, Emily L Williams, Christine A Penfold, C Ian Mockridge, Tatyana Inzhelevskaya, Jinny Kim, H T Claude Chan, Mark S Cragg, Juliet C Gray, Stephen A Beers
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundDespite extensive clinical use, the mechanisms that lead to therapeutic resistance to anti-programmed cell-death (PD)-1 monoclonal antibodies (mAbs) remain elusive. Here, we sought to determine how interactions between the Fc region of anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc1d40f038ae30462935179ccdb7a35
https://jitc.bmj.com/content/10/1/e003735.full
https://jitc.bmj.com/content/10/1/e003735.full
Autor:
Declan Lavoie, Elaine Ho, Shadi Sadeghian, Jinny Kim, Sofia Ivanesivic, Jung Park, Auva Zarandi, Dominic Hass, Sophie Zarb, David Klitovchenko, Aaron Wen, Wenteng Hou, Jake Colautti, Jeremy Penn
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6740d65a4fde7ad6e74bc73ddd56f76
https://doi.org/10.1096/fasebj.2021.35.s1.01540
https://doi.org/10.1096/fasebj.2021.35.s1.01540