Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jinny H. Kim"'
Autor:
Lekh N. Dahal, Keith W. Chan, H.T. Claude Chan, Jinny H. Kim, Chie Yin Huang, Stephen A. Beers, Andrew T M Vaughan, Abbie Mead, Priyanka Narang, Juliet X. Bowater, Martin C. Taylor, Richard J. Stopforth, Francesco Forconi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 201(4)
Rituximab is an anti-CD20 mAb used in the treatment of B cell malignancies. Loss of surface CD20 Ag from the surface of target cells is thought to be one mechanism governing resistance to rituximab, but how this occurs is not completely understood. T
Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors
Autor:
Andrew T M Vaughan, Lekh N. Dahal, Ali Roghanian, Ingrid Teige, Ruth R. French, Kerry L. Cox, Alexander Earley, Martin J. Glennie, Jinny H. Kim, Melanie S. Dunscombe, Lang Dou, Margaret Ashton-Key, Mark S. Cragg, Stephen A. Beers, C. Ian Mockridge, Stéphanie A Laversin, Elizabeth A. Potter, Björn Frendéus, Sonya James, Sean H. Lim, Christine A. Penfold, Khiyam Hussain, Alison L. Tutt, H.T. Claude Chan, Thomas R W Tipton, Chih-Chen Lu, Robert J. Oldham
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 195(11)
FcγRs are key regulators of the immune response, capable of binding to the Fc portion of IgG Abs and manipulating the behavior of numerous cell types. Through a variety of receptors, isoforms, and cellular expression patterns, they are able to fine-