Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jinni Jiang"'
MDM2 provides TOP2 poison resistance by promoting proteolysis of TOP2βcc in a p53-independent manner
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract DNA topoisomerase II (TOP2) is an enzyme that performs a critical function in manipulating DNA topology during replication, transcription, and chromosomal compaction by forming a vital intermediate known as the TOP2-DNA cleavage complex (TOP
Externí odkaz:
https://doaj.org/article/9df07424b7e843ff9c5b7c18396498a4
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/e2cd4e04991f44909ea9625bc374e7e4
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundLung adenocarcinoma (LUAD) as a frequent type of lung cancer has a 5-year overall survival rate of lower than 20% among patients with advanced lung cancer. This study aims to construct a risk model to guide immunotherapy in LUAD patients ef
Externí odkaz:
https://doaj.org/article/3a76079294da4f0bb8493cb2243e20e2