Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Jinmi Choi"'
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 2, Pp 251-263 (2024)
Abstract H3.3, the most common replacement variant for histone H3, has emerged as an important player in chromatin dynamics for controlling gene expression and genome integrity. While replicative variants H3.1 and H3.2 are primarily incorporated into
Externí odkaz:
https://doaj.org/article/df1c40ffb41e4497a46e15ac03e5348f
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
Autor:
Le Xiong, Erik A Tolen, Jinmi Choi, Sergiy Velychko, Livia Caizzi, Taras Velychko, Kenjiro Adachi, Caitlin M MacCarthy, Michael Lidschreiber, Patrick Cramer, Hans R Schöler
Publikováno v:
eLife, Vol 11 (2022)
The transcription factor Oct4 is essential for the maintenance and induction of stem cell pluripotency, but its functional roles are not fully understood. Here, we investigate the functions of Oct4 by depleting and subsequently recovering it in mouse
Externí odkaz:
https://doaj.org/article/1d5965331e63415ea1891c5a5bf6e818
Autor:
Jinmi Choi, Kseniia Lysakovskaia, Gregoire Stik, Carina Demel, Johannes Söding, Tian V Tian, Thomas Graf, Patrick Cramer
Publikováno v:
eLife, Vol 10 (2021)
Enhancer activity drives cell differentiation and cell fate determination, but it remains unclear how enhancers cooperate during these processes. Here we investigate enhancer cooperation during transdifferentiation of human leukemia B-cells to macrop
Externí odkaz:
https://doaj.org/article/2e012031dc084c85b1add7b680e595bb
Autor:
Kwanyoung Jeong, Jinmi Choi, Ahrum Choi, Joohee Shim, Young Ah Kim, Changseok Oh, Hong-Duk Youn, Eun-Jung Cho
Publikováno v:
BMB Reports. 56:252-257
Autor:
Taewan Kim, Kwanyoung Jeong, Eunji Kim, Kwanghyun Yoon, Jinmi Choi, Jae Hyeon Park, Jae-Hwan Kim, Hyung Sik Kim, Hong-Duk Youn, Eun-Jung Cho
Publikováno v:
Molecules and Cells. 45:202-215
The androgen receptor (AR) is an important therapeutic target for treating prostate cancer (PCa). Moreover, there is an increasing need for understanding the AR-independent progression of tumor cells such as neuroendocrine prostate cancer (NEPC). Men
Autor:
Eun Jung Cho, Chanhee Jo, Eun Kyoung Kim, Jinmi Choi, Sungjoon Oh, Seokjae Park, Hong Duk Youn
Publikováno v:
Experimental & Molecular Medicine
Acetylation is the most studied histone acyl modification and has been recognized as a fundamental player in metabolic gene regulation, whereas other short-chain acyl modifications have only been recently identified, and little is known about their d
Autor:
Erik A Tolen, Le Xiong, Jinmi Choi, Sergiy Velychko, Livia Caizzi, Taras Velychko, Kenjiro Adachi, Caitlin M MacCarthy, Michael Lidschreiber, Patrick Cramer, Hans R Schöler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca9e19f99e30a5e867714e090f2dbfe3
https://doi.org/10.7554/elife.71533.sa2
https://doi.org/10.7554/elife.71533.sa2
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
Autor:
Erik A Tolen, Le Xiong, Jinmi Choi, Sergiy Velychko, Livia Caizzi, Taras Velychko, Kenjiro Adachi, Caitlin M MacCarthy, Michael Lidschreiber, Patrick Cramer, Hans R Schöler
Publikováno v:
eLife.
eLife
eLife
The transcription factor Oct4 is essential for the maintenance and induction of stem cell pluripotency, but its functional roles are not fully understood. Here, we investigate the functions of Oct4 by depleting and subsequently recovering it in mouse
Autor:
Sangho Lee, Han Teo Lee, Byung Il Lee, Jae Seok Roe, Hong Duk Youn, Il Hwan Lee, Jinmi Choi, Sang Eun Lee, Sun Shin Cha, Jae Hwan Kim, Sojung Kwak, Eun Jung Cho, Bu Gyeong Kang, In Young Hwang, Min Young Suh
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3418, p 3418 (2021)
Volume 13
Issue 14
Cancers, Vol 13, Iss 3418, p 3418 (2021)
Volume 13
Issue 14
Simple Summary Among the causes of accelerating cancer properties, dysregulated transcription is considerably prominent in many cancers. However, it is difficult to target transcriptional machineries due to their fundamental importance. Compared to b
Autor:
Patrick Cramer, Hans R. Schöler, Xiong L, K. Adachi, Michael Lidschreiber, Jinmi Choi, Livia Caizzi, Tolen Ea
The transcription factor Oct4 is essential for maintaining stem cell pluripotency and for efficient cell reprogramming, but its functional roles are far from being understood. Here, we investigate the functions of Oct4 by rapidly depleting Oct4 from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5affce783b663315a63184bb88cf0cc0
https://doi.org/10.1101/2021.06.28.450119
https://doi.org/10.1101/2021.06.28.450119