Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jinkui, Niu"'
Autor:
Weiguo Jing, James Farmar, Hong Lu, Shibo Jiang, Jinkui Niu, Byron Cheung, Jane Sun, Xuxia Yan, Shuwen Liu, Shuguang Wu
Publikováno v:
Journal of Biological Chemistry. 282:9612-9620
T20 (Fuzeon), a novel anti-human immunodeficiency virus (HIV) drug, is a peptide derived from HIV-1 gp41 C-terminal heptad repeat (CHR). Its mechanism of action has not yet been defined. We applied Pepscan strategy to determine the relationship betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::270669671e32806cc8830a60f9e509e8
https://doi.org/10.1074/jbc.m609148200
https://doi.org/10.1074/jbc.m609148200
Autor:
Jinkui Niu, Shuwen Liu, Hong Lu, Shibo Jiang, Shuguang Wu, Asim Kumar Debnath, Qian Zhao, Yuxian He
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1723:270-281
Theaflavin derivatives and catechin derivatives are the major polyphenols in black tea and green tea, respectively. Several tea polyphenols, especially those with galloyl moiety, can inhibit HIV-1 replication with multiple mechanisms of action. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8e8b54fca691d514f012ecbebc7dbf
https://doi.org/10.1016/j.bbagen.2005.02.012
https://doi.org/10.1016/j.bbagen.2005.02.012
Autor:
Jinkui Niu, David S. Lawrence
Publikováno v:
Journal of Biological Chemistry. 272:1493-1499
Tyrosine-specific protein kinases are known to utilize short synthetic tyrosine-containing peptides as substrates and, as a consequence, a number of inhibitory peptides have been prepared by replacing the tyrosine moiety in these peptides with a nonp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1351ec3689771d30d6e9807f5e935b54
https://doi.org/10.1074/jbc.272.3.1493
https://doi.org/10.1074/jbc.272.3.1493
Publikováno v:
Journal of Biological Chemistry. 270:5375-5380
We report the first active site substrate specificity analysis of a tyrosine-specific protein kinase, namely pp60c−src. Like the cAMP-dependent protein kinase and protein kinase C, pp60c−src will phosphorylate an assortment of achiral residues at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0de14674ecb9ba83ec5fe0746b8c9976
https://doi.org/10.1074/jbc.270.10.5375
https://doi.org/10.1074/jbc.270.10.5375
Autor:
Shuwen, Liu, Weiguo, Jing, Byron, Cheung, Hong, Lu, Jane, Sun, Xuxia, Yan, Jinkui, Niu, James, Farmar, Shuguang, Wu, Shibo, Jiang
Publikováno v:
The Journal of biological chemistry. 282(13)
T20 (Fuzeon), a novel anti-human immunodeficiency virus (HIV) drug, is a peptide derived from HIV-1 gp41 C-terminal heptad repeat (CHR). Its mechanism of action has not yet been defined. We applied Pepscan strategy to determine the relationship betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2f9a481608b30e35e5bfcbd9b519304
https://pubmed.ncbi.nlm.nih.gov/17276993
https://pubmed.ncbi.nlm.nih.gov/17276993
Publikováno v:
Journal of Clinical Microbiology
Similar to other coronaviruses, the membrane (M) protein of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is a major transmembrane glycoprotein with multiple biological functions. To date, limited information is available about
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8879df614dd9693c6bdb1b85fa63d2c
https://pubmed.ncbi.nlm.nih.gov/16081901
https://pubmed.ncbi.nlm.nih.gov/16081901
Publikováno v:
Molecular and biochemical parasitology. 146(2)
Erythrocyte invasion by malaria parasites is a multi-step process requiring specific molecular interactions between merozoites and erythrocyte surface receptors. Human Duffy blood group protein is the receptor for Plasmodium vivax merozoite invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5f5e5955cc4f6784ef45505e5682da
https://pubmed.ncbi.nlm.nih.gov/16386320
https://pubmed.ncbi.nlm.nih.gov/16386320
Autor:
James Farmar, Jinkui Niu, Huabao Xiong, Gengfu Xiao, Yuxian He, Po Tien, Shibo Jiang, Carlos R. Escalante, Asim K. Debnath, Yibang Chen, Shuwen Liu
Publikováno v:
Lancet (London, England)
Summary Background Studies on the fusion-inhibitory peptides derived from the heptad repeat 1 and 2 (HR1 and HR2) regions of the HIV-1 envelope glycoprotein gp41 provided crucial information on the viral fusogenic mechanism. We used a similar approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de12945f30b70441dfb97abd3436d6f1
https://pubmed.ncbi.nlm.nih.gov/15043961
https://pubmed.ncbi.nlm.nih.gov/15043961
Publikováno v:
The Journal of biological chemistry. 276(12)
The three-dimensional structures of the inactive conformations of Hck and Src, members of the Src protein-tyrosine kinase family, have recently been described. In both cases, the catalytic domain lies on the opposite face of the enzyme from the SH2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::611115555e26277d943ee048732f6196
https://pubmed.ncbi.nlm.nih.gov/11118446
https://pubmed.ncbi.nlm.nih.gov/11118446
Autor:
Jinkui Niu, David S. Lawrence
Publikováno v:
Pharmacologytherapeutics. 77(2)
Inhibitors for tyrosine-specific protein kinases ultimately may constitute a novel family of medicinally active agents. Unfortunately, the challenges associated with the acquisition of inhibitors for these enzyme targets are unlike any that have ever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29fef4a2a7c22f92d59f6d133d67785
https://pubmed.ncbi.nlm.nih.gov/9578319
https://pubmed.ncbi.nlm.nih.gov/9578319