Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Jinko Graham"'
Publikováno v:
Frontiers in Genetics, Vol 13 (2023)
Introduction: In genetic epidemiology, log-linear models of population risk may be used to study the effect of genotypes and exposures on the relative risk of a disease. Such models may also include gene-environment interaction terms that allow the g
Externí odkaz:
https://doaj.org/article/14bd1a941e574d7292b6d32472494fd9
Autor:
Nirodha Epasinghege Dona, Jinko Graham
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108311- (2022)
We present simulated exome-sequencing data for 150 families from a North American admixed population, ascertained to contain at least four members affected with lymphoid cancer. These data include information on the ascertained families as well as si
Externí odkaz:
https://doaj.org/article/bc52559ca7194988918b0de4897c033f
Autor:
Charith B. Karunarathna, Jinko Graham
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background A perfect phylogeny is a rooted binary tree that recursively partitions sequences. The nested partitions of a perfect phylogeny provide insight into the pattern of ancestry of genetic sequence data. For example, sequences may clus
Externí odkaz:
https://doaj.org/article/30850a364f514cd0b219f56a07eaaa89
Autor:
Erin E. Gill, Maren L. Smith, Kristen M. Gibson, Kimberly A. Morishita, Amy H. Y. Lee, Reza Falsafi, Jinko Graham, Dirk Foell, Susanne M. Benseler, Colin J. Ross, Raashid A. Luqmani, David A. Cabral, Robert E. W. Hancock, Kelly L. Brown, The PedVas Initiative Investigators
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Objectives: Chronic primary vasculitis describes a group of complex and rare diseases that are characterized by blood vessel inflammation. Classification of vasculitis subtypes is based predominantly on the size of the involved vessels and clinical p
Externí odkaz:
https://doaj.org/article/23de446f6ddd49a0b0f1f54ed32c14dc
Autor:
Kelly L. Brown, Joanna M. Lubieniecka, Giulia Armaroli, Katharina Kessel, Kristen M. Gibson, Jinko Graham, Dongmeng Liu, Robert E. W. Hancock, Colin J. Ross, Susanne M. Benseler, Raashid A. Luqmani, David A. Cabral, Dirk Foell, Christoph Kessel
Publikováno v:
Frontiers in Pediatrics, Vol 6 (2018)
Objectives: Chronic primary systemic vasculitidies (CPV) are a collection of rare diseases involving inflammation in blood vessels, often in multiple organs. CPV can affect adults and children and may be life- or organ-threatening. Treatments for adu
Externí odkaz:
https://doaj.org/article/26eb37165e1f4ab8b69b94f4d9b9d995
Publikováno v:
Journal of Statistical Software, Vol 16, Iss 1, Pp 1-9 (2006)
We describe the R function LDheatmap() which produces a graphical display, as a heat map, of pairwise linkage disequilibrium measurements between single nucleotide polymorphisms within a genomic region. LDheatmap() uses the grid graphics system, an a
Externí odkaz:
https://doaj.org/article/d4719bf92b804d9fa4dfc41edd0e7272
Publikováno v:
Journal of Statistical Software, Vol 16, Iss 1, Pp 1-19 (2006)
Complex medical disorders, such as heart disease and diabetes, are thought to involve a number of genes which act in conjunction with lifestyle and environmental factors to increase disease susceptibility. Associations between complex traits and sing
Externí odkaz:
https://doaj.org/article/bbc40dcfefde44fdaeb8616747e692e1
Autor:
Johanna M Schuetz, Denise Daley, Jinko Graham, Brian R Berry, Richard P Gallagher, Joseph M Connors, Randy D Gascoyne, John J Spinelli, Angela R Brooks-Wilson
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31560 (2012)
Non-Hodgkin lymphomas are a heterogeneous group of solid tumours that constitute the 5(th) highest cause of cancer mortality in the United States and Canada. Poor control of cell death in lymphocytes can lead to autoimmune disease or cancer, making g
Externí odkaz:
https://doaj.org/article/bb4c466206ca4939b9b848782b4f4311
Publikováno v:
Journal of Statistical Software, Vol 21, Iss 3 (2007)
Exact inference is based on the conditional distribution of the sufficient statistics for the parameters of interest given the observed values for the remaining sufficient statistics. Exact inference for logistic regression can be problematic when da
Externí odkaz:
https://doaj.org/article/60d096e2220b41c2950b545af7d10ce9
Publikováno v:
Genetic Epidemiology. 47:78-94
Linkage analysis maps genetic loci for a heritable trait by identifying genomic regions with excess relatedness among individuals with similar trait values. Analysis may be conducted on related individuals from families, or on samples of unrelated in