Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jinhwa Kong"'
Autor:
Young Jin Kim, Sanghoon Moon, Mi Yeong Hwang, Sohee Han, Hye-Mi Jang, Jinhwa Kong, Dong Mun Shin, Kyungheon Yoon, Sung Min Kim, Jong-Eun Lee, Anubha Mahajan, Hyun-Young Park, Mark I. McCarthy, Yoon Shin Cho, Bong-Jo Kim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Metabolic traits are heritable intermediate phenotypes widely used in assessing the risk of various diseases. By conducting a genome-wide meta-analysis for metabolic traits in 288,137 East Asians, the authors highlight the interplay of common and rar
Externí odkaz:
https://doaj.org/article/a54d16a2cbba4e25a063ac117c509b5f
Autor:
Kibaick Lee, Sanghoon Moon, Mi-Jin Park, In-Uk Koh, Nak-Hyeon Choi, Ho-Yeong Yu, Young Jin Kim, Jinhwa Kong, Hee Gyung Kang, Song Cheol Kim, Bong-Jo Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5056 (2020)
This study investigated whether the promoter region of DNA methylation positively or negatively regulates tissue-specific genes (TSGs) and if it correlates with disease pathophysiology. We assessed tissue specificity metrics in five human tissues, us
Externí odkaz:
https://doaj.org/article/96458080a4e9481993d1df48610139f0
Autor:
Minoru Iwata, Jeeyun Ahn, Masao Toyoda, Shin-ichi Araki, Lucia Sobrin, Momoko Horikoshi, M Imamura, Gayatri Susarla, Shiro Maeda, Sanghoon Moon, Atsushi Takahashi, Hiroshi Maegawa, Masatoshi Matsunami, Toshimasa Yamauchi, Jinhwa Kong, Takashi Kadowaki, Kazuyuki Tobe, Kyu Hyung Park
Publikováno v:
Hum Mol Genet
Several reports have suggested that genetic susceptibility contributes to the development and progression of diabetic retinopathy. We aimed to identify genetic loci that confer susceptibility to diabetic retinopathy in Japanese patients with type 2 d
Autor:
Jun Ho Yun, Nak-Hyeon Choi, Bong-Jo Kim, Jinhwa Kong, Song Cheol Kim, Hyo Jin Kim, Ho-Yeong Yu, Kibaick Lee, Sanghoon Moon, In-Uk Koh, Song Lee
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 8, Iss 1 (2020)
BMJ Open Diabetes Research & Care
BMJ Open Diabetes Research & Care
IntroductionObesity is growing global health concern and highly associated with increased risk of metabolic diseases including type 2 diabetes. We aimed to discover new differential DNA methylation patterns predisposing obesity and prioritize surroga
Publikováno v:
BioMed Research International
BIOMED RESEARCH INTERNATIONAL
BioMed Research International, Vol 2017 (2017)
BIOMED RESEARCH INTERNATIONAL
BioMed Research International, Vol 2017 (2017)
Copy number variations (CNVs) are structural variants associated with human diseases. Recent studies verified that disease-related genes are based on the extraction of rare de novo and transmitted CNVs from exome sequencing data. The need for more ef
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2019 (2019)
BioMed Research International, Vol 2019 (2019)
Genomic analysis begins with de novo assembly of short-read fragments in order to reconstruct full-length base sequences without exploiting a reference genome sequence. Then, in the annotation step, gene locations are identified within the base seque
Autor:
Young-Jin Kim, Hee Gyung Kang, Ho Yeong Yu, Nak Hyeon Choi, Kibaick Lee, Sanghoon Moon, Bong Jo Kim, Mi Jin Park, Jinhwa Kong, In Uk Koh, Song Cheol Kim
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 5056, p 5056 (2020)
Volume 21
Issue 14
International Journal of Molecular Sciences, Vol 21, Iss 5056, p 5056 (2020)
This study investigated whether the promoter region of DNA methylation positively or negatively regulates tissue-specific genes (TSGs) and if it correlates with disease pathophysiology. We assessed tissue specificity metrics in five human tissues, us
Publikováno v:
HPCS
We present a new normalization protocol of raw WES coverage data to reduce the noise problems from variable specificities and efficiencies of the probes, which is combined with the previously developed CNV detection method based on scale-space filter
Publikováno v:
HPCS
In this research, we propose a pipeline system to identify disease-causal genes in whole exome sequencing data. The pipeline automates the execution of the following steps: 1) initial read data control and cleaning; 2) alignment to a reference genome
Publikováno v:
Korean Journal of Parasitology; Dec2016, Vol. 54 Issue 6, p751-758, 8p