Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jinhu Kim"'
Autor:
Kyung Ah Han, Taek-Han Yoon, Jinhu Kim, Jusung Lee, Ju Yeon Lee, Gyubin Jang, Ji Won Um, Jong Kyoung Kim, Jaewon Ko
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract LAR-RPTPs are evolutionarily conserved presynaptic cell-adhesion molecules that orchestrate multifarious synaptic adhesion pathways. Extensive alternative splicing of LAR-RPTP mRNAs may produce innumerable LAR-RPTP isoforms that act as regul
Externí odkaz:
https://doaj.org/article/f0e12d4eacc64673ac424ad2d9da2c9b
Autor:
Seungjoon Kim, Hyeonho Kim, Dongseok Park, Jinhu Kim, Joohyeon Hong, Jae Seong Kim, Hyeji Jung, Dongwook Kim, Eunji Cheong, Jaewon Ko, Ji Won Um
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114254- (2024)
Externí odkaz:
https://doaj.org/article/faacadb716854c0ab6ba13e824ee8db0
Autor:
Kyung Ah Han, Taek-Han Yoon, Jinhu Kim, Jusung Lee, Ju Yeon Lee, Gyubin Jang, Ji Won Um, Jong Kyoung Kim, Jaewon Ko
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5feead4c2deb44c18d11df36bea9715e
Autor:
Salima El Chehadeh, Kyung Ah Han, Dongwook Kim, Gyubin Jang, Somayeh Bakhtiari, Dongseok Lim, Hee Young Kim, Jinhu Kim, Hyeonho Kim, Julia Wynn, Wendy K. Chung, Giuseppina Vitiello, Ioana Cutcutache, Matthew Page, Jozef Gecz, Kelly Harper, Ah-reum Han, Ho Min Kim, Marja Wessels, Allan Bayat, Alberto Fernández Jaén, Angelo Selicorni, Silvia Maitz, Arjan P. M. de Brouwer, Anneke Vulto-van Silfhout, Martin Armstrong, Joseph Symonds, Sébastien Küry, Bertrand Isidor, Benjamin Cogné, Mathilde Nizon, Claire Feger, Jean Muller, Erin Torti, Dorothy K. Grange, Marjolaine Willems, Michael C. Kruer, Jaewon Ko, Amélie Piton, Ji Won Um
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The protein SLITRK2 plays an important role in synaptic communication. This study identifies X-linked SLITRK2 variants that underlie neurodevelopmental disorders by impairing excitatory synapses.
Externí odkaz:
https://doaj.org/article/939b1e803648458f978aa0c525329996
Autor:
Seungjoon Kim, Hyeonho Kim, Dongseok Park, Jinhu Kim, Joohyeon Hong, Jae Seong Kim, Hyeji Jung, Dongwook Kim, Eunji Cheong, Jaewon Ko, Ji Won Um
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1995-2005.e5 (2020)
Summary: Gephyrin interacts with various GABAergic synaptic proteins to organize GABAergic synapse development. Among the multitude of gephyrin-binding proteins is IQSEC3, a recently identified component at GABAergic synapses that acts through its AD
Externí odkaz:
https://doaj.org/article/abcefeffeb624ec2870fb07e90bed629
Autor:
Jin Young Kim, Se-Young Choi, Jinhu Kim, Jaewon Ko, Michisuke Yuzaki, Hee-Yoon Lee, Dongwook Kim, Fredrik H. Sterky, Ji Won Um, Dongseok Park, Keiko Matsuda, Hyeonho Kim, Hyeyeon Kang
Publikováno v:
J Biol Chem
Calsyntenin-3 (Clstn3) is a postsynaptic adhesion molecule that induces presynaptic differentiation via presynaptic neurexins (Nrxns), but whether Nrxns directly bind to Clstn3 has been a matter of debate. Here, using LC–MS/MS–based protein analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9011256fdf70e4a9fd88a8ab0349eb4
https://doi.org/10.1074/jbc.ra120.013077
https://doi.org/10.1074/jbc.ra120.013077
Autor:
Jinhu Kim, Seungjoon Kim, Hyeonho Kim, In-Wook Hwang, Sungwon Bae, Sudeep Karki, Dongwook Kim, Roberto Ogelman, Geul Bang, Jin Young Kim, Tommi Kajander, Ji Won Um, Won Chan Oh, Jaewon Ko
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This study demonstrates a universal synaptic mechanism responsible for tuning GABAergic neural circuit strength and turnover. These observations are relevant to the issue of neural circuit dynamics, which have only been investigated in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b86eb10cdbc0a7be37d7ae77e874e5c6
http://hdl.handle.net/10138/341857
http://hdl.handle.net/10138/341857
Autor:
Jinhu Kim, Dongseok Park, Na-Young Seo, Taek-Han Yoon, Gyu Hyun Kim, Sang-Hoon Lee, Jinsoo Seo, Ji Won Um, Kea Joo Lee, Jaewon Ko
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The present study utilized imaging, electrophysiology, and three-dimensional high-resolution electron microscopy analyses to address the neural circuit role of LRRTM3 in vivo, using both conventional and conditional Lrrtm3-KO mice. We fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d66009e79fe9765ccd2a5041cbb0996f
http://europepmc.org/articles/PMC8784129
http://europepmc.org/articles/PMC8784129
Autor:
Dongwook Kim, Hyeji Jung, Yoshinori Shirai, Hyeonho Kim, Jinhu Kim, Dongseok Lim, Takuma Mori, Hyojeong Lee, Dongseok Park, Hee Young Kim, Qi Guo, Bo Pang, Wen Qiu, Xueshan Cao, Emi Kouyama-Suzuki, Takeshi Uemura, Enas Kasem, Yu Fu, Seungjoon Kim, Akinori Tokunaga, Takahiro Yoshizawa, Tatsuo Suzuki, Hiroyuki Sakagami, Kea Joo Lee, Jaewon Ko, Katsuhiko Tabuchi, Ji Won Um
Publikováno v:
Biological psychiatry. 91(9)
IQSEC3, a gephyrin-binding GABAergic (gamma-aminobutyric acidergic) synapse-specific guanine nucleotide exchange factor, was recently reported to regulate activity-dependent GABAergic synapse maturation, but the underlying signaling mechanisms remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e225be7c78e962aea2d7b8fc3c950099
https://pubmed.ncbi.nlm.nih.gov/35219498
https://pubmed.ncbi.nlm.nih.gov/35219498
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Members of the Slitrk (Slit- and Trk-like protein) family of synaptic cell-adhesion molecules control excitatory and inhibitory synapse development through isoform-dependent extracellular interactions with leukocyte common antigen-related receptor pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9957b5b1719cc5ded8118b1973a299b2
http://link.springer.com/article/10.1038/s41598-019-53519-1
http://link.springer.com/article/10.1038/s41598-019-53519-1