Výsledky vyhledávání - "Jinhong Qian"

Akademický článek

Endoscopic endonasal transsphenoidal surgery for unusual sellar lesions: eight cases and review of the literature

Autor: Jiandong Wu, Peng Deng, Jinhong Qian, Yanli Lu, Zhiliang Ding, Xiaolong Hu, Yuhui Gong, Xiaoyu Tang, Mian Ma

Publikováno v: Frontiers in Neurology, Vol 15 (2024)

BackgroundPreoperative imaging for some unusual lesions in the sellar region can pose challenges in establishing a definitive diagnosis, impacting treatment strategies.MethodsThis study is a retrospective analysis of eight cases involving unusual sel

Externí odkaz: https://doaj.org/article/62c681707e8e459e8336a07d3025375a

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Gasdermin D serves as a key executioner of pyroptosis in experimental cerebral ischemia and reperfusion model both in vivo and in vitro

Autor: Gang Chen, Haitao Shen, Peng Zhang, Xiang Li, Jinhong Qian, Dongping Zhang, Haiying Li

Publikováno v: Journal of neuroscience research. 97(6)

Even though ischemic stroke is among the leading causes of death worldwide, the pathogenic mechanisms underlying ischemia reperfusion (I/R) brain injury remain unclear. Gasdermin D (GSDMD), as an important factor of pyroptotic death execution downstr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0aa0503ff6f5bf2963b8ffa11436230
https://pubmed.ncbi.nlm.nih.gov/30600840

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Effects of SC99 on cerebral ischemia-perfusion injury in rats: Selective modulation of microglia polarization to M2 phenotype via inhibiting JAK2-STAT3 pathway

Autor: Gang Chen, Yi-Ping Ding, Jinhong Qian, Xiang Li, Zhuan Xu, Haiying Li, Yan Kong, Haitao Shen

Publikováno v: Neuroscience research. 142

Inhibition of Janus kinases 2-Signal transducers and activators of transcription3 (JAK2-STAT3) pathway has been shown to exert anti-inflammatory actions. SC99, a novel specific inhibitor targeting JAK2-STAT3 pathway, has been verified to negatively m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505c52b503ae8bf52155ec6ee7cd3320
https://pubmed.ncbi.nlm.nih.gov/29763638

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