Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jinhang Zhang"'
Autor:
Jinhang Zhang, Ya Huang, Hong Li, Pengfei Xu, Qinhui Liu, Yang Sun, Zijing Zhang, Tong Wu, Qin Tang, Qingyi Jia, Yan Xia, Ying Xu, Xiandan Jing, Jiahui Li, Li Mo, Wen Xie, Aijuan Qu, Jinhan He, Yanping Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Pregnane X receptor (PXR) has been reported to regulate glycolipid metabolism. The dysfunction of intestinal barrier contributes to metabolic disorders. However, the role of intestinal PXR in metabolic diseases remains largely unknown. Here,
Externí odkaz:
https://doaj.org/article/c585118dd2cb442cb8c2dbc63eae7924
Autor:
Ying Xu, Yan Xia, Qinhui Liu, Xiandan Jing, Qin Tang, Jinhang Zhang, Qingyi Jia, Zijing Zhang, Jiahui Li, Jiahao Chen, Yimin Xiong, Yanping Li, Jinhan He
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 12, Pp 1548-1561 (2023)
Excessive N-acetyl-p-benzoquinone imine (NAPQI) formation is a starting event that triggers oxidative stress and subsequent hepatocyte necrosis in acetaminophen (APAP) overdose caused acute liver failure (ALF). S-glutathionylation is a reversible red
Externí odkaz:
https://doaj.org/article/063c7bc8b2f447eda513b9fc63f26214
Autor:
Jinhang Zhang, Jing Yang
Publikováno v:
Iranian Journal of Public Health, Vol 51, Iss 4 (2022)
Abstract Background: Intake of allium vegetables may modify the risk of breast cancer. The aim of this study was to examine the association between allium vegetables intake and breast cancer risk via a meta-analysis. Methods: PubMed, Web of Kno
Externí odkaz:
https://doaj.org/article/c87f223cea394e669a4328dd52b7cdec
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
ObjectiveThis study aims to comprehensively evaluate the prognostic impact of the surgical margin in hepatectomy on patients diagnosed with hepatocellular carcinoma (HCC).MethodsA comprehensive and systematic search for eligible articles published in
Externí odkaz:
https://doaj.org/article/9eb1c2d4a61e4541b625f5faf0ce3861
Autor:
Xuping Yang, Qinhui Liu, Yanping Li, Qin Tang, Tong Wu, Lei Chen, Shiyun Pu, Yingnan Zhao, Guorong Zhang, Cuiyuan Huang, Jinhang Zhang, Zijing Zhang, Ya Huang, Min Zou, Xiongjie Shi, Wei Jiang, Rui Wang, Jinhan He
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 484-494 (2020)
The diabetes medication canagliflozin (Cana) is a sodium glucose cotransporter 2 (SGLT2) inhibitor acting by increasing urinary glucose excretion and thus reducing hyperglycaemia. Cana treatment also reduces body weight. However, it remains unclear w
Externí odkaz:
https://doaj.org/article/6af5c4ed9b494dcbaec0f4ee17d251b8
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Liver fibrosis is end-stage liver disease that can be rescued. If irritation continues due to viral infection, schistosomiasis and alcoholism, liver fibrosis can progress to liver cirrhosis and even cancer. The US Food and Drug Administration has not
Externí odkaz:
https://doaj.org/article/58f517150ba14c2e9fbd90e1f5c13c15
Autor:
Jian Zhou, Rui Li, Qinhui Liu, Jinhang Zhang, Hui Huang, Cuiyuan Huang, Guorong Zhang, Yingnan Zhao, Tong Wu, Qin Tang, Ya Huang, Zijing Zhang, Yanping Li, Jinhan He
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss , Pp 111470- (2021)
The enzyme 5-lipoxygenase (5-LO) converts arachidonic acid to leukotrienes, which mediate inflammation. The enzyme is known to contribute to organ fibrosis, but how it contributes to renal fibrosis is unclear. Here, we reported that fibrotic kidneys
Externí odkaz:
https://doaj.org/article/28feb3e5b0434afc9a95682d89887458
Autor:
Shiyun Pu, Yanping Li, Qinhui Liu, Xu Zhang, Lei Chen, Rui Li, Jinhang Zhang, Tong Wu, Qin Tang, Xuping Yang, Zijing Zhang, Ya Huang, Jiangying Kuang, Hong Li, Min Zou, Wei Jiang, Jinhan He
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background and Purpose: Activation of hepatic stellate cells (HSC) is a central driver of liver fibrosis. 5-lipoxygenase (5-LO) is the key enzyme that catalyzes arachidonic acid into leukotrienes. In this study, we examined the role of 5-LO in HSC ac
Externí odkaz:
https://doaj.org/article/5d4b3915c3bf4b0ebd852a77c304c260
Autor:
Qin Tang, Yong Gao, Qinhui Liu, Xuping Yang, Tong Wu, Cuiyuan Huang, Ya Huang, Jinhang Zhang, Zijing Zhang, Rui Li, Shiyun Pu, Guorong Zhang, Yingnan Zhao, Jian Zhou, Hui Huang, Yanping Li, Wei Jiang, Yongsheng Chang, Jinhan He
Publikováno v:
Molecular Metabolism, Vol 37, Iss , Pp 100994- (2020)
Objective: Sirt6 is an essential regulator of energy metabolism in multiple peripheral tissues. However, the direct role of Sirt6 in the hypothalamus, specifically pro-opiomelanocortin (POMC) neurons, controlling energy balance has not been establish
Externí odkaz:
https://doaj.org/article/82d10c381a254b99a579af28b2459b29
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Sirt6 is one of the sirtuin family members, a kind of NAD+-dependent histone deacetylase and ADP-ribose transferase enzyme. It has an important role in physiological and pathological processes, regulating aging, cancer, obesity, insulin resistance, i
Externí odkaz:
https://doaj.org/article/f7361caec1b145728b5cba626624168a