Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Jinha Yu"'
Autor:
Kisu Sung, Sehwan Oh, Hong-Rae Kim, Seokhwan Hyeon, Jin-Hyun Ahn, Suyeon Kim, Vikas R. Aswar, Sushil K. Tripathi, Jinha Yu, Lak Shin Jeong
Publikováno v:
Results in Chemistry, Vol 11, Iss , Pp 101765- (2024)
MLN4924 (1), a neddylation inhibitor, has shown promising anticancer and antiviral properties. In this study, we designed and synthesized new derivatives of 4′-oxo-MLN4924, inspired by the structures of MLN4924 and another known neddylation inhibit
Externí odkaz:
https://doaj.org/article/4d364243752542668d94f8fa465fb255
Autor:
Sujin Park, Yujin Ahn, Yongchan Kim, Eun Joo Roh, Yoonji Lee, Chaebin Han, Hee Min Yoo, Jinha Yu
Publikováno v:
Molecules, Vol 27, Iss 13, p 4016 (2022)
Adenosine mediates various physiological activities in the body. Adenosine receptors (ARs) are widely expressed in tumors and the tumor microenvironment (TME), and they induce tumor proliferation and suppress immune cell function. There are four type
Externí odkaz:
https://doaj.org/article/42f34fea159d4ebe9f76349c367ae2e5
Autor:
Chau Ha Pham, Joo-Eun Lee, Jinha Yu, Sung Hoon Lee, Kyung-Rok Yu, Jaewoo Hong, Namki Cho, Seil Kim, Dukjin Kang, Soojin Lee, Hee Min Yoo
Publikováno v:
Molecules, Vol 26, Iss 16, p 4951 (2021)
Recent studies found that short-chain fatty acids (SCFAs), which are produced through bacterial fermentation in the gastrointestinal tract, have oncoprotective effects against cervical cancer. The most common SCFAs that are well known include acetic
Externí odkaz:
https://doaj.org/article/94ac87b2000a405aa019611d66f70da5
Publikováno v:
Pharmaceuticals, Vol 14, Iss 4, p 363 (2021)
A new series of 4′-selenoadenosine-5′-N,N-dimethyluronamide derivatives as highly potent and selective human A3 adenosine receptor (hA3AR) antagonists, is described. The highly selective A3AR agonists, 4′-selenoadenosine-5′-N-methyluronamides
Externí odkaz:
https://doaj.org/article/71e21cae6c2d437fbe2e2c04c97d90db
Publikováno v:
Slovenian Veterinary Research, Vol 55, Iss 3 (2018)
Hemato-biochemical and histopathological alterations in mud loach (Misgurnus mizolepis) infected with Aeromonas sobria were characterized in the present study. Fish infected with 1 × 106 colony forming units/mL of A. sobria (25 fish × 3 replicates
Externí odkaz:
https://doaj.org/article/9cb9130a199146fabaa5f8b2b6015357
Autor:
Pramod K. Sahu, Tamima Umme, Jinha Yu, Gyudong Kim, Shuhao Qu, Siddhi D. Naik, Lak Shin Jeong
Publikováno v:
Molecules, Vol 22, Iss 7, p 1167 (2017)
A series of acyclic selenopurine nucleosides 3a–f and 4a–g were synthesized based on the bioisosteric rationale between oxygen and selenium, and then evaluated for antiviral activity. Among the compounds tested, seleno-acyclovir (4a) exhibited th
Externí odkaz:
https://doaj.org/article/106486db5a6d4a68a1b1cacfc6e1cc57
Autor:
Anna Shiriaeva, Daejin Park, Gyudong Kim, Yoonji Lee, Xiyan Hou, Dnyandev B. Jarhad, Gibae Kim, Jinha Yu, Young Eum Hyun, Woomi Kim, Zhan-Guo Gao, Kenneth A. Jacobson, Gye Won Han, Raymond C. Stevens, Lak Shin Jeong, Sun Choi, Vadim Cherezov
Publikováno v:
Journal of Medicinal Chemistry. 65:11648-11657
Autor:
Lijun Jia, Ziming Dong, Robert M. Hoffman, Meng Yang, Hui Qi, Lak Shin Jeong, Jinha Yu, Shengli Yang, Hu Zhao, Yanmei Zhang, Ping Zhang, Jinwu Wang, Qianyun Hao, Yangcheng Ma, Jingyang Zhang, Xiaoyu Chen, Pei Li, Yupei Liang, Tao Hu, Ping Chen
Purpose: Targeting the protein neddylation pathway has become an attractive anticancer strategy; however, the role of death receptor–mediated extrinsic apoptosis during treatment remained to be determined.Experimental Design: The activation of extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca4ba1127d17481789069d25aeb964b
https://doi.org/10.1158/1078-0432.c.6523101
https://doi.org/10.1158/1078-0432.c.6523101
Autor:
Lijun Jia, Ziming Dong, Robert M. Hoffman, Meng Yang, Hui Qi, Lak Shin Jeong, Jinha Yu, Shengli Yang, Hu Zhao, Yanmei Zhang, Ping Zhang, Jinwu Wang, Qianyun Hao, Yangcheng Ma, Jingyang Zhang, Xiaoyu Chen, Pei Li, Yupei Liang, Tao Hu, Ping Chen
supplemental legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90759b7bed18b24c0847b04ac4a585d7
https://doi.org/10.1158/1078-0432.22455738.v1
https://doi.org/10.1158/1078-0432.22455738.v1
Autor:
Lijun Jia, Ziming Dong, Robert M. Hoffman, Meng Yang, Hui Qi, Lak Shin Jeong, Jinha Yu, Shengli Yang, Hu Zhao, Yanmei Zhang, Ping Zhang, Jinwu Wang, Qianyun Hao, Yangcheng Ma, Jingyang Zhang, Xiaoyu Chen, Pei Li, Yupei Liang, Tao Hu, Ping Chen
Supplementary Table S1. Clinicopathologic parameters according to the expression of NAE1, UBA3 and UBC12. Supplementary Table S2. Clinicopathologic parameters according to the expression of global neddylation (global NEDD 8 conjugation).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d44c54d42d466293995d11a51c727ac
https://doi.org/10.1158/1078-0432.22455741.v1
https://doi.org/10.1158/1078-0432.22455741.v1