Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jingzhi Lou"'
Autor:
Jingzhi Lou, Weiwen Liang, Lirong Cao, Inchi Hu, Shi Zhao, Zigui Chen, Renee Wan Yi Chan, Peter Pak Hang Cheung, Hong Zheng, Caiqi Liu, Qi Li, Marc Ka Chun Chong, Yexian Zhang, Eng-kiong Yeoh, Paul Kay-Sheung Chan, Benny Chung Ying Zee, Chris Ka Pun Mok, Maggie Haitian Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Influenza virus continuously evolves to escape human adaptive immunity and generates seasonal epidemics. Therefore, influenza vaccine strains need to be updated annually for the upcoming flu season to ensure vaccine effectiveness. We develop
Externí odkaz:
https://doaj.org/article/fc847cb633ec405d9ec7b0e6d698d42f
Autor:
Shi Zhao, Inchi Hu, Jingzhi Lou, Marc K.C. Chong, Lirong Cao, Daihai He, Benny C.Y. Zee, Maggie H. Wang
Publikováno v:
Infectious Disease Modelling, Vol 8, Iss 1, Pp 107-121 (2023)
Virus evolution is a common process of pathogen adaption to host population and environment. Frequently, a small but important fraction of virus mutations are reported to contribute to higher risks of host infection, which is one of the major determi
Externí odkaz:
https://doaj.org/article/55d9008a260b4954bd51aad13b6e0403
Autor:
Jingzhi Lou, Hong Zheng, Shi Zhao, Lirong Cao, Eliza LY Wong, Zigui Chen, Renee WY Chan, Marc KC Chong, Benny CY Zee, Paul KS Chan, Eng-kiong Yeoh, Maggie H Wang
Publikováno v:
Journal of Infection and Public Health, Vol 15, Iss 3, Pp 338-342 (2022)
Background: The coronavirus disease 2019 (COVID-19) pandemic has become a major public health threat. This study aims to evaluate the effect of virus mutation activities and policy interventions on COVID-19 transmissibility in Hong Kong. Methods: In
Externí odkaz:
https://doaj.org/article/6d0d783286e2464b9f65521a924c0642
Autor:
Shi Zhao, Jingzhi Lou, Lirong Cao, Hong Zheng, Marc K. C. Chong, Zigui Chen, Renee W. Y. Chan, Benny C. Y. Zee, Paul K. S. Chan, Maggie H. Wang
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background The COVID-19 pandemic poses serious threats to global health, and the emerging mutation in SARS-CoV-2 genomes, e.g., the D614G substitution, is one of the major challenges of disease control. Characterizing the role of the mutatio
Externí odkaz:
https://doaj.org/article/486435eb2dd74abcb4ff95026fb2c8c3
Autor:
Lirong Cao, Shi Zhao, Qi Li, Lowell Ling, William K. K. Wu, Lin Zhang, Jingzhi Lou, Marc K. C. Chong, Zigui Chen, Eliza L. Y. Wong, Benny C. Y. Zee, Matthew T. V. Chan, Paul K. S. Chan, Maggie H. Wang
Publikováno v:
Royal Society Open Science, Vol 8, Iss 9 (2021)
The novel coronavirus disease 2019 (COVID-19) has spread worldwide and threatened human life. Diagnosis is crucial to contain the spread of SARS-CoV-2 infections and save lives. Diagnostic tests for COVID-19 have varying sensitivity and specificity,
Externí odkaz:
https://doaj.org/article/2ab0909357b543518a9e664ae6e8064c
Autor:
Jingzhi Lou, Shi Zhao, Lirong Cao, Marc K.C. Chong, Renee W.Y. Chan, Paul K.S. Chan, Benny C.Y. Zee, Eng-Kiong Yeoh, Maggie H. Wang
Publikováno v:
International Journal of Infectious Diseases, Vol 100, Iss , Pp 255-257 (2020)
Objectives: Characterizing and predicting the evolutionary process of influenza, which remain challenging, are of importance in capturing the patterns of influenza activities and for developing prevention and control strategies. This study quantified
Externí odkaz:
https://doaj.org/article/a75187ed8d9f4239bc0cc65039fca225
Autor:
Lirong Cao, Shi Zhao, Jingzhi Lou, Hong Zheng, Renee W. Y. Chan, Marc K. C. Chong, Zigui Chen, Paul K. S. Chan, Benny C. Y. Zee, Maggie H. Wang
Publikováno v:
Viruses, Vol 13, Iss 4, p 619 (2021)
Assessment of influenza vaccine effectiveness (VE) and identification of relevant influencing factors are the current priorities for optimizing vaccines to reduce the impacts of influenza. To date, how the difference between epidemic strains and vacc
Externí odkaz:
https://doaj.org/article/6077ff53841546f4b8f8e198c8bef8b9
Autor:
Shi Zhao, Jingzhi Lou, Marc K. C. Chong, Lirong Cao, Hong Zheng, Zigui Chen, Renee W. Y. Chan, Benny C. Y. Zee, Paul K. S. Chan, Maggie H. Wang
Publikováno v:
Viruses, Vol 13, Iss 4, p 638 (2021)
As COVID-19 is posing a serious threat to global health, the emerging mutation in SARS-CoV-2 genomes, for example, N501Y substitution, is one of the major challenges against control of the pandemic. Characterizing the relationship between mutation ac
Externí odkaz:
https://doaj.org/article/56e8eb58e8384c799d99a93373a30030
Autor:
Lirong Cao, Jingzhi Lou, See Yeung Chan, Hong Zheng, Caiqi Liu, Shi Zhao, Qi Li, Chris Ka Pun Mok, Renee Wan Yi Chan, Marc Ka Chun Chong, William Ka Kei Wu, Zigui Chen, Eliza Lai Yi Wong, Paul Kay Sheung Chan, Benny Chung Ying Zee, Eng Kiong Yeoh, Maggie Haitian Wang
Publikováno v:
Nature Medicine. 28:1715-1722
Timely evaluation of the protective effects of Coronavirus Disease 2019 (COVID-19) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern is urgently needed to inform pandemic control planning. Based on 78 v
Autor:
Jingzhi Lou, Shi Zhao, Lirong Cao, Hong Zheng, Zigui Chen, Renee W.Y. Chan, Marc K.C. Chong, Benny C.Y. Zee, Paul K.S. Chan, Maggie H. Wang
Publikováno v:
Public Health Genomics. 25:108-111
During coronavirus disease 2019 (COVID-19) pandemic, the genetic mutations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred frequently. Some mutations in the spike protein are considered to promote transmissibility of the viru