Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jingzhen Lai"'
Autor:
Wudi Wei, Gang Wang, Hong Zhang, Xiuli Bao, Sanqi An, Qiang Luo, Jinhao He, Lixiang Chen, Chuanyi Ning, Jingzhen Lai, Zongxiang Yuan, Rongfeng Chen, Junjun Jiang, Li Ye, Hao Liang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Talaromyces marneffei (T. marneffei) immune escape is essential in the pathogenesis of talaromycosis. It is currently known that T. marneffei achieves immune escape through various strategies. However, the role of cellular alternative splici
Externí odkaz:
https://doaj.org/article/b7997288c66042a6b982ba3953cb3ad5
Talaromyces marneffei activates the AIM2-caspase-1/-4-GSDMD axis to induce pyroptosis in hepatocytes
Autor:
Gang Wang, Wudi Wei, Zhongsheng Jiang, Junjun Jiang, Jing Han, Hong Zhang, Jiaguang Hu, Peng Zhang, Xu Li, Tao Chen, Jinhao He, Zhen Li, Jingzhen Lai, Hao Liang, Chuanyi Ning, Li Ye
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 963-979 (2022)
Talaromyces marneffei tends to induce systemic infection in immunocompromised individuals, which is one of the causes of the high mortality. The underlying molecular mechanisms of T.marneffei-induced abnormal liver function are still poorly understoo
Externí odkaz:
https://doaj.org/article/37574121793c4fc8a081ad4190219a20
Autor:
Yu Zhang, Zhiman Xie, Jie Zhou, Yanjun Li, Chuanyi Ning, Qisi Su, Li Ye, Sufang Ai, Jingzhen Lai, Peijiang Pan, Ningmei Liu, Yanyan Liao, Qijian Su, Zhuoxin Li, Hao Liang, Ping Cui, Jiegang Huang
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundThe immune activation caused by microbial translocation has been considered to be a major driver of HIV infection progression. The dysbiosis of gut microbiota has been demonstrated in HIV infection, but the interplay between gut microbiota
Externí odkaz:
https://doaj.org/article/10a33adf347e44199891411ae6e8a534
Autor:
Wudi Wei, Chuanyi Ning, Jiegang Huang, Gang Wang, Jingzhen Lai, Jing Han, Jinhao He, Hong Zhang, Bingyu Liang, Yanyan Liao, Thuy Le, Qiang Luo, Zhen Li, Junjun Jiang, Li Ye, Hao Liang
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1997-2012 (2021)
Little is known about how Talaromyces marneffei, a thermally dimorphic fungus that causes substantial morbidity and mortality in Southeast Asia, evades the human immune system. Polarization of macrophages into fungal-inhibiting M1-like and fungal-pro
Externí odkaz:
https://doaj.org/article/94d6f9ed88cd4ac0a81b5ab24be5b0ab
Publikováno v:
International Journal of Infectious Diseases, Vol 120, Iss , Pp 48-50 (2022)
ABSTRACT: Intestinal Talaromyces marneffei (TM) infection among patients with HIV/AIDS is rare. Herein, we report 31 cases of intestinal TM infection in Guangxi. Most patients exhibited fever, lymphadenectasis in the abdominal cavity, and chronic int
Externí odkaz:
https://doaj.org/article/24de57cd4d7d466ab80b6934f77dab01
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-4 (2021)
Abstract Background Varicella-zoster virus (VZV) infection may induce central nervous system complications in HIV/AIDS patients. However, it is rare to have paraplegia caused by VZV infection but no herpes zoster clinically. Asymptomatic VZV infectio
Externí odkaz:
https://doaj.org/article/598782b909704f459389f9b7a084de26
Autor:
Shanfang Qin, Jingzhen Lai, Hong Zhang, Di Wei, Qing Lv, Xue Pan, Lihua Huang, Ke Lan, Zhihao Meng, Hao Liang, Chuanyi Ning
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background In the era of anti-retroviral therapy (ART), the plasma HIV viral load (VL) is an important primary indicator for monitoring the HIV treatment response. To optimize the clinical management of HIV/AIDS patients, we investigated VL
Externí odkaz:
https://doaj.org/article/1827d45f60714d05831cb0580cfb1e8c
Autor:
Yunxuan Huang, Oulu Zhou, Zhigang Zheng, Yuexiang Xu, Yi Shao, Chunwei Qin, Fengxiang Qin, Jingzhen Lai, Huifang Liu, Rongfeng Chen, Li Ye, Hao Liang, Xionglin Qin, Junjun Jiang
Publikováno v:
AIDS Research and Therapy, Vol 17, Iss 1, Pp 1-9 (2020)
Abstract Objective To evaluate the impact of AIDS-defining events (ADE) on long-term mortality of HIV positive individuals on antiretroviral therapy (ART), a retrospective HIV/AIDS treatment cohort study performed in Southwestern China. Methods The r
Externí odkaz:
https://doaj.org/article/c612e3c1257244b99a519fa26e279d37
Autor:
Junjun Jiang, Xi Hu, Wenwei Li, Jie Liu, Bingyu Liang, Hui Chen, Jiegang Huang, Ning Zang, Chuanyi Ning, Yanyan Liao, Rongfeng Chen, Jingzhen Lai, Jiemei Chu, Peijiang Pan, Ping Cui, Qiao Tang, Xiu Chen, Hao Liang, Li Ye
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Innate immunity is the first line of defense against invading pathogens and may mediate HIV-1 resistance in HIV-1–exposed seronegative (HESN) individuals. This study aims to identify components of innate immunity that confer natural HIV-1 resistanc
Externí odkaz:
https://doaj.org/article/51465511a55f42c59d693ad3aa9f97f2
Autor:
Jingzhen Lai, Chunwei Qin, Eric J. Nehl, Junjun Jiang, Yunxuan Huang, Bingyu Liang, Yuexiang Xu, Jiegang Huang, Zhiliang Xu, Chuanyi Ning, Yanyan Liao, Ning Zang, Wudi Wei, Fengxiang Qin, Jun Yu, Li Ye, Xionglin Qin, Hao Liang
Publikováno v:
BMC Public Health, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Female sex workers (FSW) are a population that are at high risk for HIV infection, and their HIV/AIDS knowledge levels and sexual behaviors are of concern. This study describes changes in HIV prevalence and factors associated amon
Externí odkaz:
https://doaj.org/article/979e634fa01c40c3bcbcd41d54dfe5d5