Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jingyun Luan"'
Autor:
Xiaozhi Hu, Jiajun Fan, Qianqian Ma, Lei Han, Zhonglian Cao, Caili Xu, Jingyun Luan, Guangjun Jing, Yanyang Nan, Tao Wu, Yuting Zhang, Hanqi Wang, Yuanzhen Zhang, Dianwen Ju
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is a metabolic disease mainly on account of hypercholesterolemia and may progress to cirrhosis and hepatocellular carcinoma. The discovery of effective therapy for NAFLD is an essential unm
Externí odkaz:
https://doaj.org/article/5dbeba4e36234562bc58ecedb43f8322
Autor:
Jinghui Zhang, Jiajun Fan, Xian Zeng, Mingming Nie, Wei Chen, Yichen Wang, Jingyun Luan, Zeguo Zhu, Xusheng Chang, Dianwen Ju, Li Feng, Kai Yin
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/0d3d1ff5ec29462c966731c6dfb2c9f8
Autor:
Xiaomiao Ye, Peng Zhang, Yuting Zhang, Jingyun Luan, Caili Xu, Zhengyu Wu, Dianwen Ju, Wei Hu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundGasdermin D (GSDMD) plays an essential role in the pathway of pyroptosis. However, whether GSDMD participates in myocardial ischaemia/reperfusion injury (MI/RI) remains poorly understood.MethodsSerum levels of GSDMD and IL-18 in ST-segment
Externí odkaz:
https://doaj.org/article/4a0b8c61fe0f4f8aba192dcda567c285
Autor:
Jinghui Zhang, Jiajun Fan, Xian Zeng, Mingming Nie, Jingyun Luan, Yichen Wang, Dianwen Ju, Kai Yin
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 609-620 (2021)
The Hedgehog (HH) signaling pathway plays important roles in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment (TME). Aberrant HH signaling activation may accelerate the growth of gastrointestinal tumors and lead to tumo
Externí odkaz:
https://doaj.org/article/f8862e162fa14769b5e6aade93337d7e
Autor:
Jinghui Zhang, Jiajun Fan, Xian Zeng, Mingming Nie, Wei Chen, Yichen Wang, Jingyun Luan, Zeguo Zhu, Xusheng Chang, Dianwen Ju, Li Feng, Kai Yin
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Abstract Trastuzumab emtansine (T-DM1), an antibody-drug conjugate consisted of the HER2-targeted monoclonal antibody trastuzumab and the tubulin inhibitor emtansine, has shown potent therapeutic value in HER2-positive breast cancer (BC). However, a
Externí odkaz:
https://doaj.org/article/3acfe4c4adc94a10838d6d381091855f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic kidney injury has gradually become a worldwide public health problem currently affecting approximately 10% of the population and can eventually progress to chronic end-stage renal disease characteristic by the result of epithelial atrophy. In
Externí odkaz:
https://doaj.org/article/59f82dc3e77d4c82b3165fb2d888edda
Autor:
Xuyao Zhang, Yichen Wang, Jiajun Fan, Wei Chen, Jingyun Luan, Xiaobin Mei, Shaofei Wang, Yubin Li, Li Ye, Song Li, Wenzhi Tian, Kai Yin, Dianwen Ju
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background Inhibitors targeting VEGF and VEGFR are commonly used in the clinic, but only a subset of patients could benefit from these inhibitors and the efficacy was limited by multiple relapse mechanisms. In this work, we aimed to investig
Externí odkaz:
https://doaj.org/article/ce87a851c9474d56ac93ac2110d12aaf
Autor:
Wei Chen, Yilan Shen, Jiajun Fan, Xian Zeng, Xuyao Zhang, Jingyun Luan, Yichen Wang, Jinghui Zhang, Si Fang, Xiaobin Mei, Zhen Zhao, Dianwen Ju
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 2, Pp n/a-n/a (2021)
Abstract Kidney damage initiates the deteriorating metabolic states in tubule cells that lead to the development of end‐stage renal disease (ESTD). Interleukin‐22 (IL‐22) is an effective therapeutic antidote for kidney injury via promoting kidn
Externí odkaz:
https://doaj.org/article/bf9b9a4e7c534c9b80aa0fe378121b0b
Autor:
Shaofei Wang, Jiajun Fan, Xiaobin Mei, Jingyun Luan, Yubin Li, Xuyao Zhang, Wei Chen, Yichen Wang, Guangxun Meng, Dianwen Ju
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Aristolochic acid nephropathy (AAN), as a rapidly progressive interstitial nephropathy due to excessive ingestion of aristolochia herbal medications, has recently raised considerable concerns among clinicians and researchers as its underlying pathoge
Externí odkaz:
https://doaj.org/article/21e3f69c5c614293be5458512ce52e36
Autor:
Jingyun Luan, Dianwen Ju
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Inflammasomes have emerged as critical innate sensors of host immune that defense against pathogen infection, metabolism syndrome, cellular stress and cancer metastasis in the liver. The assembly of inflammasome activates caspase-1, which promotes th
Externí odkaz:
https://doaj.org/article/04438a8e53a84a9993767077fa08730b