Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jingyue Jia"'
Publikováno v:
Cell Stress, Vol 5, Iss 9, Pp 128-142 (2021)
The yeast Atg8 protein and its paralogs in mammals, mammalian Atg8s (mAtg8s), have been primarily appreciated for their participation in autophagy. However, lipidated mAtg8s, including the most frequently used autophagosomal membrane marker LC3B, are
Externí odkaz:
https://doaj.org/article/b8641ad6b399426f9926d568d3c87248
Autor:
Jingyue Jia, Yongxin Jin, Ting Bian, Donghai Wu, Lijun Yang, Naohiro Terada, Weihui Wu, Shouguang Jin
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91547 (2014)
Transcription Activator-Like Effector Nucleases (TALENs) are a novel class of sequence-specific nucleases that have recently gained prominence for its ease of production and high efficiency in genome editing. A TALEN pair recognizes specific DNA sequ
Externí odkaz:
https://doaj.org/article/f8d2f42f64044cd393a1ec0752b0fb86
Autor:
Jingyue Jia, Fulong Wang, Zambarlal Bhujabal, Ryan Peters, Michal Mudd, Thabata Duque, Lee Allers, Ruheena Javed, Michelle Salemi, Christian Behrends, Brett Phinney, Terje Johansen, Vojo Deretic
The functions of mammalian Atg8 proteins (mATG8s) expand beyond canonical autophagy and include processes collectively referred to as Atg8ylation. Global modulation of protein synthesis under stress conditions is governed by MTOR and liquid-liquid ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8db0c8dd17373e1b18ed0c4f55f695b
https://hdl.handle.net/10037/28760
https://hdl.handle.net/10037/28760
Autor:
Jingyue Jia, Fulong Wang, Zambarlal Bhujabal, Ryan Peters, Michal Mudd, Thabata Duque, Lee Allers, Ruheena Javed, Michelle Salemi, Christian Behrends, Brett Phinney, Terje Johansen, Vojo Deretic
Publikováno v:
The Journal of cell biology, vol 221, iss 11
We report that lysosomal damage is a hitherto unknown inducer of stress granule (SG) formation and that the process termed membrane atg8ylation coordinates SG formation with mTOR inactivation during lysosomal stress. SGs were induced by lysosome-dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d178b2f3218551a0b49bb5427fb653
https://hdl.handle.net/10037/28759
https://hdl.handle.net/10037/28759
Autor:
Jingyue Jia, Graham S. Timmins, Lukas Brecht, Yuexi Gu, Vojo Deretic, Bhawana Bissa, Lee Allers, Kenneth R. Hallows, Christian Behrends, Seong Won Choi, Mark R. Burge, Mark Zbinden
Publikováno v:
Autophagy
Lysosomal damage activates AMPK, a regulator of macroautophagy/autophagy and metabolism, and elicits a strong ubiquitination response. Here we show that the cytosolic lectin LGALS9 detects lysosomal membrane breach by binding to lumenal glycoepitopes
Autor:
Sandeep Pallikkuth, Brett S. Phinney, Aurore Claude-Taupin, Lee Allers, Michal H. Mudd, Michelle Salemi, Bhawana Bissa, Ryan Peters, Yuexi Gu, Muriel Mari, Keith A. Lidke, Fulvio Reggiori, Jingyue Jia, Vojo Deretic, Seong Won Choi
Publikováno v:
Autophagy, vol 16, iss 8
Autophagy, 16(8), 1539-1541. Taylor & Francis Group
Autophagy
Autophagy, 16(8), 1539-1541. Taylor & Francis Group
Autophagy
Membrane integrity is essential for cellular survival and function. The spectrum of mechanisms protecting cellular and intracellular membranes is not fully known. Our recent work has uncovered a cellular system termed MERIT for lysosomal membrane rep
Autor:
Keith A. Lidke, Aurore Claude-Taupin, Luciana Jesus da Costa, Yasuo Uchiyama, Michelle Salemi, Jingyue Jia, Muriel Mari, Suresh Kumar, Sandeep Pallikkuth, Fulvio Reggiori, Fulong Wang, Pauline Verlhac, Terje Johansen, Gustavo Peixoto Duarte da Silva, Zambarlal Bhujabal, Meriem Garfa-Traoré, Mario Mauthe, Yuexi Gu, Brett S. Phinney, Ruheena Javed, Sharon A. Tooze, Vojo Deretic, Ryan Peters, Lee Allers
Publikováno v:
Nature Cell Biology
Nature Cell Biology, 23(8). Nature Publishing Group
Nature cell biology, vol 23, iss 8
Nature Cell Biology, 23(8). Nature Publishing Group
Nature cell biology, vol 23, iss 8
The integral membrane protein ATG9A plays a key role in autophagy. It displays a broad intracellular distribution and is present in numerous compartments, including the plasma membrane (PM). The reasons for the distribution of ATG9A to the PM and its
Autor:
Graham S. Timmins, Kenneth R. Hallows, Jingyue Jia, Seong Won Choi, Bhawana Bissa, Vojo Deretic, Mark Zbinden, Lee Allers, Lukas Brecht, Mark R. Burge, Christian Behrends, Yuexi Gu
Publikováno v:
Mol Cell
AMPK is a central regulator of metabolism and autophagy. Here we show how lysosomal damage activates AMPK. This occurs via a hitherto unrecognized signal transduction system whereby cytoplasmic sentinel lectins detect membrane damage leading to ubiqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18acee093ef9b07f9f33ed920b2a3459
https://europepmc.org/articles/PMC7785494/
https://europepmc.org/articles/PMC7785494/
Autor:
Vojo Deretic, Keith A. Lidke, Sandeep Pallikkuth, Muriel Mari, Fulvio Reggiori, Aurore Claude-Taupin, Lee Allers, Seong Won Choi, Michelle Salemi, Brett S. Phinney, Yuexi Gu, Jingyue Jia, Bhawana Bissa, Ryan Peters, Michal H. Mudd
Publikováno v:
Developmental cell, vol 52, iss 1
Dev Cell
Developmental Cell, 52(1), 69-+. CELL PRESS
Dev Cell
Developmental Cell, 52(1), 69-+. CELL PRESS
Summary Endomembrane damage elicits homeostatic responses including ESCRT-dependent membrane repair and autophagic removal of damaged organelles. Previous studies have suggested that these systems may act separately. Here, we show that galectin-3 (Ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635da3d6f52053f5c2267bcf651e5ee2
https://escholarship.org/uc/item/8kw6p2js
https://escholarship.org/uc/item/8kw6p2js
Publikováno v:
Seminars in Cell & Developmental Biology. 83:36-41
The autophagy pathway known also as macroautophagy (herein referred to as autophagy) is characterized by the formation of double-membrane organelles that capture cytosolic material. Based on pathway termination alternatives, autophagy has been divide