Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Jingyuan, Wan"'
Publikováno v:
Discover Applied Sciences, Vol 6, Iss 10, Pp 1-14 (2024)
Abstract Non-alcoholic steatohepatitis (NASH) is a predominant metabolic liver disease, typically characterized by hepatic steatosis, oxidative stress, and inflammation. The traditional Chinese medicine Cornus officinalis possesses anti-inflammatory
Externí odkaz:
https://doaj.org/article/679bd1c5995b44a1a08162c1b7088103
Autor:
Kerui Fan, Kun Chen, Xinyan Zan, Ying Zhi, Xue Zhang, Xinyue Zhang, Jinghuan Qiu, Gang Liu, Longjiang Li, Li Tang, Kai Hu, Jingyuan Wan, Xianqiong Gong, Yongqiang Yang, Li Zhang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-14 (2023)
Abstract Accumulating evidence indicates that metabolic responses are deeply integrated into signal transduction, which provides novel opportunities for the metabolic control of various disorders. Recent studies suggest that itaconate, a highly conce
Externí odkaz:
https://doaj.org/article/f85218518b7a463ea609c5c6d1ece5bb
Autor:
Xian Yang, Qingsong Jiang, Tiankuo Luan, Chao Yu, Zhibo Liu, Ting Wang, Jingyuan Wan, Jiayu Huang, Ke Li
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Osteoarthritis (OA) is a common disease characterized by cartilage degradation. Growing evidence showed that glucose metabolism impacts joint homeostasis and an imbalance between glycolysis and oxidative phosphorylation (OXPHOS) may exacerba
Externí odkaz:
https://doaj.org/article/ee2c62f103f2413d891d952de5e5fad2
Autor:
Zizuo Zhao, Tiankuo Luan, Jingyuan Wan, Hui Du, Jun Hu, Hao Liu, Xia Gong, Ge Kuang, Bin Wang
Publikováno v:
Medicina, Vol 59, Iss 9, p 1639 (2023)
Background and Objectives: Non-alcoholic steatohepatitis (NASH) is a significant risk factor for hepatocellular carcinoma (HCC) development. Timely treatment during the NASH stage is essential to minimize the possibility of disease progression to HCC
Externí odkaz:
https://doaj.org/article/09d4b2feb54b40cd857cc18de77f50e9
Autor:
Hui Du, Shiwen Tong, Ge Kuang, Xia Gong, Ningman Jiang, Xian Yang, Hao Liu, Nana Li, Yao Xie, Yang Xiang, Jiashi Guo, Zhenhan Li, Yinglin Yuan, Shengwang Wu, Jingyuan Wan
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
Acetaminophen (APAP) overdose would lead to liver toxicity and even acute liver failure in severe cases by triggering an inflammatory response and oxidative stress. Sesamin has been reported to possess anti-inflammatory and antioxidant actions in sev
Externí odkaz:
https://doaj.org/article/8b33094399f342358214c23f43f5563e
Autor:
Jun Hu, Hui Du, Yinglin Yuan, Peipei Guo, Junxia Yang, Xinru Yin, Jin Liu, Shengwang Wu, Jingyuan Wan, Xia Gong
Publikováno v:
Mediators of Inflammation, Vol 2022 (2022)
Nonalcoholic steatohepatitis (NASH) is the common liver disease characterized by hepatic steatosis, inflammation, and fibrosis; there are no approved drugs to treat this disease because of incomplete understanding of pathophysiological mechanisms of
Externí odkaz:
https://doaj.org/article/ac57e950aa2b4b41b6eccd424d1654b4
Autor:
Tiankuo Luan, Daqiang Song, Jiazhou Liu, Yuxian Wei, Rui Feng, Xiaoyu Wang, Lin Gan, Jingyuan Wan, Huiying Fang, Hongzhong Li, Xia Gong
Publikováno v:
Medicina, Vol 59, Iss 3, p 424 (2023)
Background and Objectives. The prognostic role of adjacent nontumor tissue in patients with breast cancer (BC) is still unclear. The activity changes in immunologic and hallmark gene sets in normal tissues adjacent to BC may play a crucial role in pr
Externí odkaz:
https://doaj.org/article/a44167336bae437e8bcf526940a6e8bd
Autor:
Suqiong Huang1 Jiangxinhui@cqmu.edu.cn, Jingyuan Wan1, Tingting Du1, Tao Gong1, Jing Zhang1, Xinhui Jiang1
Publikováno v:
Journal of Chinese Pharmaceutical Sciences. Jun2022, Vol. 31 Issue 6, p441-451. 11p.
Autor:
Xianwen Peng, Yongqiang Yang, Li Tang, Jingyuan Wan, Jie Dai, Longjiang Li, Jiayi Huang, Yi Shen, Ling Lin, Xianqiong Gong, Li Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 125, Iss , Pp 110020- (2020)
The excessive generation of reactive oxygen species (ROS) plays crucial roles in the development of acute liver injury. Nicotinamide adenine dinucleotide phosphate oxidase (NOX) is responsible for the robust production of ROS under inflammatory circu
Externí odkaz:
https://doaj.org/article/b2176678221645a0a97dd9acd92b31fc
Autor:
Sen Yang, Ge Kuang, Liangke Zhang, Shengwang Wu, Zizuo Zhao, Bin Wang, Xinru Yin, Xia Gong, Jingyuan Wan
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Acute liver injury and its terminal phase, hepatic failure, trigger a series of complications, including hepatic encephalopathy, systematic inflammatory response syndrome, and multiorgan failure, with relatively high morbidity and mortality. Liver tr
Externí odkaz:
https://doaj.org/article/8f27fc8b7a8a47208a9bf006712a9c47