Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Jingyuan, Fang"'
Autor:
Pengjie Yang, Jinzhong Tian, Lu Zhang, Hui Zhang, Gaohua Yang, Yimeng Ren, Jingyuan Fang, Yang Gu, Weihong Jiang
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 1, Pp 43-54 (2024)
Gut microbes are closely related with human health, but remain much to learn. Clostridium symbiosum is a conditionally pathogenic human gut bacterium and regarded as a potential biomarker for early diagnosis of intestinal tumors. However, the absence
Externí odkaz:
https://doaj.org/article/f2acde9e8ed441268fb2b545fbfc58ce
Autor:
Jinci Yan, Chengli Fang, Gaohua Yang, Jianxu Li, Yanqiang Liu, Lu Zhang, Pengjie Yang, Jingyuan Fang, Yang Gu, Yu Zhang, Weihong Jiang
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Berberine (BBR) is a commonly used anti-intestinal inflammation drug, and its anti-cancer activity has been found recently. BBR can intervene and control malignant colorectal cancer (CRC) through intestinal microbes, but the direc
Externí odkaz:
https://doaj.org/article/9a83a7854e6b4c9ca86918aecf56ec71
Autor:
Yun Qian, Ziran Kang, Licong Zhao, Huimin Chen, Chengbei Zhou, Qinyan Gao, Zheng Wang, Qiang Liu, Yun Cui, Xiaobo Li, Yingxuan Chen, Tianhui Zou, Jingyuan Fang, Jinjiao Li, Yuanyuan Ji
Publikováno v:
Chinese Medical Journal, Vol 136, Iss 22, Pp 2722-2731 (2023)
Abstract. Background:. Colorectal carcinogenesis and progression are related to the gut microbiota and the tumor immune microenvironment. Our previous clinical trial demonstrated that berberine (BBR) hydrochloride might reduce the recurrence and canc
Externí odkaz:
https://doaj.org/article/d9a0346f8c494f02ad7ec80893123e3f
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTColorectal cancer (CRC) is the third most common malignant tumor worldwide. The incidence and mortality rates of CRC have been increasing in China, possibly due to economic development, lifestyle, and dietary changes. Evidence suggests that g
Externí odkaz:
https://doaj.org/article/4dd45183219f48cba35ab1906cae9004
Autor:
You Li, Zhiqiang Li, Ruiling Chen, Min Lian, Hanxiao Wang, Yiran Wei, Zhengrui You, Jun Zhang, Bo Li, Yikang Li, Bingyuan Huang, Yong Chen, Qiaoyan Liu, Zhuwan Lyu, Xueying Liang, Qi Miao, Xiao Xiao, Qixia Wang, Jingyuan Fang, YongYong Shi, Xiangdong Liu, Michael F. Seldin, M. Eric Gershwin, Ruqi Tang, Xiong Ma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Primary biliary cholangitis is a rare, chronic immune-mediated liver disease triggered by environmental exposures in genetically susceptible individuals. Here, the authors investigate the functional mechanism underlying the association of 19p13.3 var
Externí odkaz:
https://doaj.org/article/c3bffe3f09684055a2d88786709182d8
Autor:
Yong Chen, Xiangwei Hua, Bingyuan Huang, Stella Karsten, Zhengrui You, Bo Li, You Li, Yikang Li, Jubo Liang, Jun Zhang, Yiran Wei, Ruiling Chen, Zhuwan Lyu, Xiao Xiao, Min Lian, Jue Wei, Jingyuan Fang, Qi Miao, Qixia Wang, Ulrika Warpman Berglung, Ruqi Tang, Thomas Helleday, Xiong Ma
Publikováno v:
Hepatology Communications, Vol 6, Iss 5, Pp 1016-1031 (2022)
Autoimmune hepatitis (AIH) is an inflammatory liver disease driven by the hyperactivation of various intrahepatic antigen‐specific T cells due to a breach of immune tolerance. Studies in immunometabolism demonstrate that activated T cells harbor in
Externí odkaz:
https://doaj.org/article/2d8f714164314a3ebac9af9b639b9dbc
Autor:
Yan Li, Chen Yang, Zhicheng Liu, Shangce Du, Susan Can, Hailin Zhang, Linmeng Zhang, Xiaowen Huang, Zhenyu Xiao, Xiaobo Li, Jingyuan Fang, Wenxin Qin, Chong Sun, Cun Wang, Jun Chen, Huimin Chen
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-16 (2022)
Abstract Background In recent years, the application of functional genetic immuno-oncology screens has showcased the striking ability to identify potential regulators engaged in tumor-immune interactions. Although these screens have yielded substanti
Externí odkaz:
https://doaj.org/article/5c4e9dcc453b4fe196b346340c7d3c5c
Autor:
Yichao Hou, Lidan Hou, Yu Liang, Qingwei Zhang, Xialu Hong, Yu Wang, Xin Huang, Ting Zhong, Wenjing Pang, Ci Xu, Liming Zhu, Lei Li, Jingyuan Fang, Xiangjun Meng
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 11, Pp 590-603 (2020)
Most colorectal cancer (CRC) are characterized by allele loss of the genes located on the short arm of chromosome 17 (17p13.1), including the tumor suppressor p53 gene. Although important, p53 is not the only driver of chromosome 17p loss. In this st
Externí odkaz:
https://doaj.org/article/8772f0ba48734c419080c0c63c91b3b0
Autor:
Bo Li, Jun Zhang, Yong Chen, Qixia Wang, Li Yan, Rui Wang, Yiran Wei, Zhengrui You, Yikang Li, Qi Miao, Xiao Xiao, Min Lian, Weihua Chen, Dekai Qiu, Jingyuan Fang, M. Eric Gershwin, Ruqi Tang, Xiong Ma
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
Background: Increasing data suggests an interaction between bile acids and intestinal microbiota in the pathogenesis of primary biliary cholangitis (PBC). Bile acid sequestrants are widely used to bind bile acids in the intestinal lumen and are there
Externí odkaz:
https://doaj.org/article/e1c0c45acbbc40dc916bc2a966f68bbd
Autor:
Xiaowen Huang, Xialu Hong, Jilin Wang, Tiantian Sun, TaChung Yu, Yanan Yu, Jingyuan Fang, Hua Xiong
Publikováno v:
EBioMedicine, Vol 61, Iss , Pp 103037- (2020)
Background: The effect of metformin on gut microbiota has been reported, but whether metformin can suppress colorectal cancer (CRC) by affecting gut microbiota composition and rescue F. nucleatum-induced tumourigenicity remains unclear. Methods: To i
Externí odkaz:
https://doaj.org/article/e1c6d091fb7a4eec835882416412e53a