Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Jingyao, Mu"'
Tryptophan As a New Member of RNA‐Induced Silencing Complexes Prevents Colon Cancer Liver Metastasis
Autor:
Fangyi Xu, Yi Ren, Yun Teng, Jingyao Mu, Jie Tang, Kumaran Sundaram, Lifeng Zhang, Juw Won Park, Jae Yeon Hwang, Jun Yan, Gerald Dryden, Huang‐Ge Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 31, Pp n/a-n/a (2024)
Abstract Essential amino acids (EAA) and microRNAs (miRs) control biological activity of a cell. Whether EAA regulates the activity of miR has never been demonstrated. Here, as proof‐of‐concept, a tryptophan (Trp, an EAA) complex containing Argon
Externí odkaz:
https://doaj.org/article/70b19b6668ac4a169c60d6e13864d25a
Autor:
Mukesh K. Sriwastva, Yun Teng, Jingyao Mu, Fangyi Xu, Anil Kumar, Kumaran Sundaram, Rajiv Kumar Malhotra, Qingbo Xu, Joshua L. Hood, Lifeng Zhang, Jun Yan, Michael L. Merchant, Juw Won Park, Gerald W. Dryden, Nejat K. Egilmez, Huang‐Ge Zhang
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 2, Pp n/a-n/a (2023)
Abstract Extracellular vesicles (EVs) contain more than 100 proteins. Whether there are EVs proteins that act as an ‘organiser’ of protein networks to generate a new or different biological effect from that identified in EV‐producing cells has
Externí odkaz:
https://doaj.org/article/33c5cd4cf6cb4bf493fc823ff60c3791
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
Autor:
Anil Kumar, Kumaran Sundaram, Jingyao Mu, Gerald W. Dryden, Mukesh K. Sriwastva, Chao Lei, Lifeng Zhang, Xiaolan Qiu, Fangyi Xu, Jun Yan, Xiang Zhang, Juw Won Park, Michael L. Merchant, Henry C. L. Bohler, Baomei Wang, Shuangqin Zhang, Chao Qin, Ziying Xu, Xianlin Han, Craig J. McClain, Yun Teng, Huang-Ge Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
High-fat diet plays a role in development of insulin resistance. Here, the authors report a mechanism that underlies the development of diet induced insulin resistance through the activation of an aryl hydrocarbon receptor mediated signalling pathway
Externí odkaz:
https://doaj.org/article/197f808e92ba42869b26bfd32025af49
Autor:
Chao Lei, Yun Teng, Liqing He, Mohammed Sayed, Jingyao Mu, Fangyi Xu, Xiangcheng Zhang, Anil Kumar, Kumaran Sundaram, Mukesh K. Sriwastva, Lifeng Zhang, Shao-yu Chen, Wenke Feng, Shuangqin Zhang, Jun Yan, Juw Won Park, Michael L. Merchant, Xiang Zhang, Huang-Ge Zhang
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102511- (2021)
Summary: Diet and bile play critical roles in shaping gut microbiota, but the molecular mechanism underlying interplay with intestinal microbiota is unclear. Here, we showed that lemon-derived exosome-like nanoparticles (LELNs) enhance lactobacilli t
Externí odkaz:
https://doaj.org/article/b5e9d9b7a12441eda91e86920d613a65
Autor:
Kumaran Sundaram, Daniel P. Miller, Anil Kumar, Yun Teng, Mohammed Sayed, Jingyao Mu, Chao Lei, Mukesh K. Sriwastva, Lifeng Zhang, Yan Jun, Michael L. Merchant, Liqing He, Yuan Fang, Shuangqin Zhang, Xiang Zhang, Juw W. Park, Richard J. Lamont, Huang-Ge Zhang
Publikováno v:
iScience, Vol 21, Iss , Pp 308-327 (2019)
Summary: Plant exosomes protect plants against infection; however, whether edible plant exosomes can protect mammalian hosts against infection is not known. In this study, we show that ginger exosome-like nanoparticles (GELNs) are selectively taken u
Externí odkaz:
https://doaj.org/article/6ea73ef561a24b2e9ba6d89fb6910c70
Autor:
Chao Lei, Jingyao Mu, Yun Teng, Liqing He, Fangyi Xu, Xiangcheng Zhang, Kumaran Sundaram, Anil Kumar, Mukesh K. Sriwastva, Matthew B. Lawrenz, Lifeng Zhang, Jun Yan, Wenke Feng, Craig J. McClain, Xiang Zhang, Huang-Ge Zhang
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101571- (2020)
Summary: Clostridioides difficile (C. diff) is the leading cause of antibiotic-associated colitis. Here, we report that lemon exosome-like nanoparticles (LELNs) manipulated probiotics to inhibit C. diff infection (CDI). LELN-manipulated Lactobacillus
Externí odkaz:
https://doaj.org/article/6828d49f0d0149b3964486692b400d20
Autor:
Kumaran Sundaram, Daniel P. Miller, Anil Kumar, Yun Teng, Mohammed Sayed, Jingyao Mu, Chao Lei, Mukesh K. Sriwastva, Lifeng Zhang, Jun Yan, Michael L. Merchant, Liqing He, Yuan Fang, Shuangqin Zhang, Xiang Zhang, Juw W. Park, Richard J. Lamont, Huang-Ge Zhang
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Externí odkaz:
https://doaj.org/article/f5cc5c05d013498eb12f34e2a850a4d9
Autor:
Yun Teng, Yi Ren, Xin Hu, Jingyao Mu, Abhilash Samykutty, Xiaoying Zhuang, Zhongbin Deng, Anil Kumar, Lifeng Zhang, Michael L. Merchant, Jun Yan, Donald M. Miller, Huang-Ge Zhang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Exosomes are involved in the development of metastasis but how their composition is regulated is not well known. Here the authors propose that major vault protein-dependent loading of miR-193a into exosomes could be a general mechanism by which cance
Externí odkaz:
https://doaj.org/article/403d807f4d76457f9f8de1dbcd525283
Autor:
Huang-Ge Zhang, Donald Miller, Jun Yan, Baomei Wang, Lifeng Zhang, Jingyao Mu, Xiaoying Zhuang, Zhong-Bin Deng, Qilong Wang, Xiaohua Li, Ping Wang, Hong Jiang
PDF file - 27K, Figure S4. Activation of Mekk2/Erk5 pathway is required for tumor cells to escape NK cell-mediated immunosurveillance.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bc265970f3757a20e05e2ae5f3367c
https://doi.org/10.1158/2326-6066.22537163
https://doi.org/10.1158/2326-6066.22537163
Autor:
Huang-Ge Zhang, Donald Miller, Jun Yan, Baomei Wang, Lifeng Zhang, Jingyao Mu, Xiaoying Zhuang, Zhong-Bin Deng, Qilong Wang, Xiaohua Li, Ping Wang, Hong Jiang
Aberrant microRNA (miRNA) expression has been identified in various human solid cancers. However, whether the levels of miRNA expression in tumor cells have any effect on tumor progression has not been determined. In this proof-of-concept study, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9546f1b23ccc2ae3553e522fb3c8a9e
https://doi.org/10.1158/2326-6066.c.6548336.v1
https://doi.org/10.1158/2326-6066.c.6548336.v1