Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Jingyan Xue"'
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-9 (2024)
Abstract Branch retinal vein occlusion (BRVO) is the most prevalent retinal vascular disease that constitutes a threat to vision due to increased venous pressure caused by venous effluent in the space, leading to impaired visual function. Optical Coh
Externí odkaz:
https://doaj.org/article/44ebd63c631d419eb8cc3dae6b04f1e0
Autor:
Min He, Shuang Hao, LinXiaoxi Ma, BingQiu Xiu, BenLong Yang, ZeHao Wang, JingYan Xue, YaYun Chi, Min Xiong, JiaJian Chen, XiaoYan Huang, XiYu Liu, SongYang Wu, Qin Xiao, Yan Huang, RuoHong Shui, AYong Cao, JunJie Li, GenHong Di, WenTao Yang, Xin Hu, GuangYu Liu, KeDa Yu, YiZhou Jiang, ZhongHua Wang, ZhiMing Shao, Jiong Wu
Publikováno v:
EClinicalMedicine, Vol 74, Iss , Pp 102700- (2024)
Summary: Background: Toripalimab, a novel PD-1 antibody, is approved for treatment of multiple solid tumors; however, its neoadjuvant use with chemotherapy for triple-negative breast cancer (TNBC) remains unevaluated. Additionally, induction chemothe
Externí odkaz:
https://doaj.org/article/8620611ec0bb4bdcbdb47cc79155784e
Autor:
Xuliren Wang, Weiru Chi, Yuwei Ma, Qi Zhang, Jingyan Xue, Zhi-Ming Shao, Bingqiu Xiu, Jiong Wu, Yayun Chi
Publikováno v:
Translational Oncology, Vol 46, Iss , Pp 102016- (2024)
Background: Breast cancer (BC) poses a global threat, with HER2-positive BC being a particularly hazardous subtype. Despite the promise shown by neoadjuvant therapy (NAT) in improving prognosis, resistance in HER2-positive BC persists despite emergin
Externí odkaz:
https://doaj.org/article/2514a4bfd9e3487d9296ddd490662d95
Publikováno v:
Cancer Medicine, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Background Sentinel lymph node biopsy (SLNB) is a common choice for axillary surgery in patients with early‐stage breast cancer (BC) who have clinically negative lymph nodes. Most research indicates that obesity is a prognostic factor for
Externí odkaz:
https://doaj.org/article/565ea4076c0048a0b117321a7aaef8f9
Autor:
Rong Guo, Yonghui Su, Qi Zhang, Bingqiu Xiu, Sheng Huang, Weiru Chi, Liyi Zhang, Lun Li, Jianjing Hou, Jia Wang, Jiajian Chen, Yayun Chi, Jingyan Xue, Jiong Wu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Background Metastasis is the predominant cause of mortality in patients with breast cancer. Long noncoding RNAs (lncRNAs) have been shown to drive important phenotypes in tumors, including invasion and metastasis. However, the lncRNAs involv
Externí odkaz:
https://doaj.org/article/4574cf99d9e54594b4d5704430f7fefd
Autor:
Yonghui Su, Yuchen Li, Rong Guo, Jingjing Zhao, Weiru Chi, Hongyan Lai, Jia Wang, Zhen Wang, Lun Li, Yuting Sang, Jianjing Hou, Jingyan Xue, Zhimin Shao, Yayun Chi, Shenglin Huang, Jiong Wu
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract A large number RNAs are enriched and stable in extracellular vesicles (EVs), and they can reflect their tissue origins and are suitable as liquid biopsy markers for cancer diagnosis and treatment efficacy prediction. In this study, we used e
Externí odkaz:
https://doaj.org/article/dfa050c358e744b8a02a818c92ba2c3c
Autor:
Qi Zhang, Xiaoyan Huang, Ming Chen, Lun Li, Benlong Yang, Jiong Wu, Shenglin Huang, Rong Guo, Zhi-Ming Shao, Bingqiu Xiu, Liyi Zhang, Weiru Chi, Jingyan Xue, Yayun Chi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background Despite the success of HER2-targeted therapy in achieving prolonged survival in approximately 50% of treated individuals, treatment resistance is still an important challenge for HER2+ breast cancer (BC) patients. The influence of both ada
Externí odkaz:
https://doaj.org/article/a0d49a05909f4f0b9b74697a2abaa0d7
Autor:
Xuliren Wang, Fangdie Ye, Min Xiong, Bingqiu Xiu, Weiru Chi, Qi Zhang, Jingyan Xue, Ming Chen, Liyi Zhang, Jiong Wu, Yayun Chi
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Breast cancer (BC) is the most common malignant tumour, and its heterogeneity is one of its major characteristics. N6-methyladenosine (m6A), N1-methyladenosine (m1A), alternative polyadenylation (APA), and adenosine-to-inosine (A-to-I) RN
Externí odkaz:
https://doaj.org/article/531f2d33504e44688b4353e92a761acd
Autor:
Jing Si, Rong Guo, Bingqiu Xiu, Weiru Chi, Qi Zhang, Jianjing Hou, Yonghui Su, Jiajian Chen, Jingyan Xue, Zhi-Ming Shao, Jiong Wu, Yayun Chi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundBreast cancer is one of the leading causes of cancer-related death among women, and the pathological status of axillary lymph nodes is an important predictor of prognosis. However, the mechanism involved in this early stage of metastasis re
Externí odkaz:
https://doaj.org/article/10777c2049fb426bb83c3e72cfc0110b
Autor:
Wei Wang, Mingqi Li, Suriyan Ponnusamy, Yayun Chi, Jingyan Xue, Beshoy Fahmy, Meiyun Fan, Gustavo A. Miranda-Carboni, Ramesh Narayanan, Jiong Wu, Zhao-Hui Wu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Genotoxic agents have been shown to activate the Wnt/β-catenin signaling but the underlying mechanism remains unclear. Here, the authors show that upon DNA damage, the deubiquitinase OTULIN activates Wnt/β-catenin signaling by inhibiting linear ubi
Externí odkaz:
https://doaj.org/article/b4496d310ec64236a21571f5bea2d9bf