Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Jingxin, Fu"'
Autor:
Mike Mason, Óscar Lapuente-Santana, Anni S. Halkola, Wenyu Wang, Raghvendra Mall, Xu Xiao, Jacob Kaufman, Jingxin Fu, Jacob Pfeil, Jineta Banerjee, Verena Chung, Han Chang, Scott D. Chasalow, Hung Ying Lin, Rongrong Chai, Thomas Yu, Francesca Finotello, Tuomas Mirtti, Mikko I. Mäyränpää, Jie Bao, Emmy W. Verschuren, Eiman I. Ahmed, Michele Ceccarelli, Lance D. Miller, Gianni Monaco, Wouter R. L. Hendrickx, Shimaa Sherif, Lin Yang, Ming Tang, Shengqing Stan Gu, Wubing Zhang, Yi Zhang, Zexian Zeng, Avinash Das Sahu, Yang Liu, Wenxian Yang, Davide Bedognetti, Jing Tang, Federica Eduati, Teemu D. Laajala, William J. Geese, Justin Guinney, Joseph D. Szustakowski, Benjamin G. Vincent, David P. Carbone
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Predictive biomarkers of immune checkpoint inhibitor (ICI) efficacy are currently lacking for non-small cell lung cancer (NSCLC). Here, we describe the results from the Anti–PD-1 Response Prediction DREAM Challenge, a crowdsourc
Externí odkaz:
https://doaj.org/article/c3635bd5bd234a2da3cffc46f246670f
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 2539-2548 (2022)
Oleic acid (OA) is a kind of monounsaturated omega-3 fatty acid that abounds in plants and animals which can induce apoptosis and has broad-spectrum inhibitory activity against a variety of tumor cell lines. However, OA is quite insoluble and thus in
Externí odkaz:
https://doaj.org/article/7ce701010e1e4dff996ec703ef11313e
Autor:
Likang Lu, Hui Ao, Jingxin Fu, Manzhen Li, Yaoyao Guo, Yifei Guo, Meihua Han, Rongxing Shi, Xiangtao Wang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 163, Iss , Pp 114870- (2023)
Ginsenosides are the major and key components for ginseng to exert its wide and beneficial therapeutic efficacy in clinic. Meanwhile, many ginsenosides and their metabolites showed in vitro an in vivo anti-tumor activity, among which ginsenoside Rb1
Externí odkaz:
https://doaj.org/article/c5b66139c3f543ada6f7f373cd80b53e
Autor:
Hui Ao, Zhuo Wang, Likang Lu, Hongwei Ma, Haowen Li, Jingxin Fu, Manzhen Li, Meihua Han, Yifei Guo, Xiangtao Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Most intravenously administered drug-loaded nanoparticles are taken up by liver Kupffer cells, and only a small portion can accumulate at the tumor, resulting in an unsatisfactory therapeutic efficacy and side effects for chemothe
Externí odkaz:
https://doaj.org/article/1865932036184b47ad942349f0dff453
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1335 (2023)
Neutral/negatively charged nanoparticles are beneficial to reduce plasma protein adsorption and prolong their blood circulation time, while positively charged nanoparticles easily transverse the blood vessel endothelium into a tumor and easily penetr
Externí odkaz:
https://doaj.org/article/80983b04a616492ca73713cb4cc82e84
Publikováno v:
Molecules, Vol 28, Iss 6, p 2753 (2023)
Protein N-glycosylation is a common post-translational modification that plays significant roles on the structure, property, and function of glycoproteins. Due to N-glycan heterogeneity of naturally occurring glycoproteins, the functions of specific
Externí odkaz:
https://doaj.org/article/a6352b834e6b463ba6c215294954cef4
Publikováno v:
Drug Delivery, Vol 28, Iss 1, Pp 1226-1236 (2021)
Quercetin-loaded nanosuspensions (Que-NSps) added metabolic inhibitors were evaluated as drug delivery system to promote the oral bioavailability of quercetin. Que-NSps were prepared respectively using d-alpha tocopherol acid polyethylene glycol succ
Externí odkaz:
https://doaj.org/article/99d15222fa394fed878997b1718ca974
Autor:
Shengqing Stan Gu, Xiaoqing Wang, Xihao Hu, Peng Jiang, Ziyi Li, Nicole Traugh, Xia Bu, Qin Tang, Chenfei Wang, Zexian Zeng, Jingxin Fu, Cliff Meyer, Yi Zhang, Paloma Cejas, Klothilda Lim, Jin Wang, Wubing Zhang, Collin Tokheim, Avinash Das Sahu, Xiaofang Xing, Benjamin Kroger, Zhangyi Ouyang, Henry Long, Gordon J. Freeman, Myles Brown, X. Shirley Liu
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-28 (2020)
Abstract Background Immune checkpoint blockade (ICB) therapy has improved patient survival in a variety of cancers, but only a minority of cancer patients respond. Multiple studies have sought to identify general biomarkers of ICB response, but eluci
Externí odkaz:
https://doaj.org/article/b3244746e20a48e2bb9e322dbec655a3
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-8 (2020)
Abstract Despite growing numbers of immune checkpoint blockade (ICB) trials with available omics data, it remains challenging to evaluate the robustness of ICB response and immune evasion mechanisms comprehensively. To address these challenges, we in
Externí odkaz:
https://doaj.org/article/37eda81c7b9a4d1fa4405315e20f6e9a
Autor:
Yian Wang, Tiantian Huang, Haowen Li, Jingxin Fu, Hui Ao, Likang Lu, Meihua Han, Yifei Guo, Feng Yue, Xiangtao Wang
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 228-237 (2020)
Due to their various biological activities that are beneficial to human health and antitumor effect, flavonoid compounds have attracted much attention in recent years. Hydrous icaritin (HICT) was such a flavonoid that can inhibit the growth of breast
Externí odkaz:
https://doaj.org/article/eb671a5223194b278ebc7d3e679c7e19